Results 31 to 40 of about 1,383,394 (337)
Human pluripotent stem cells offer the best available model to study the underlying cellular and molecular mechanisms of human embryonic lineage specification.
Li-Fang Chu +9 more
semanticscholar +1 more source
Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. [PDF]
Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult.
Chen, Di +7 more
core +2 more sources
The embryonic microenvironment is well known to be non-permissive for tumor development because early developmental signals naturally suppress the expression of proto-oncogenes.
Shufeng Zhou +4 more
semanticscholar +1 more source
Stem Cells from a Biological Perspective in Animals: A Review [PDF]
Cells are the smallest living units of living system. Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide to produce more stem cells.
Jain, A. (Archana) +2 more
core +1 more source
MELK-a conserved kinase: functions, signaling, cancer, and controversy. [PDF]
Maternal embryonic leucine zipper kinase (MELK) is a highly conserved serine/threonine kinase initially found to be expressed in a wide range of early embryonic cellular stages, and as a result has been implicated in embryogenesis and cell cycle control.
Beullens, Monique +5 more
core +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Epidemiological studies have demonstrated that interleukin-10 (IL-10) polymorphisms may be associated with the development of Behcet’s disease (BD). However, the published results were inconsistent. Therefore, this meta-analysis was conducted to derive a
Xue-Feng Li +4 more
doaj +1 more source
Tracking the embryonic stem cell transition from ground state pluripotency
Mouse embryonic stem (ES) cells are locked into self-renewal by shielding from inductive cues. Release from this ground state in minimal conditions offers a system for delineating developmental progression from naïve pluripotency.
Tüzer Kalkan +13 more
semanticscholar +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Stem Cell Therapeutics: Exploring Newer Alternatives to Human Embryonic Stem Cells [PDF]
Stem cells therapeutics has come a long way since stem cells and their potential was discovered for the first time. Intense research into cellular biology of stem cells has revealed that they possess immense potential for curing many human diseases ...
Garg, Abhishek D.
core

