Results 191 to 200 of about 571,903 (350)

Derivation of Transgene-Free Rat Induced Pluripotent Stem Cells Approximating the Quality of Embryonic Stem Cells [PDF]

, 2016
Shuping Li, He Lan, Hongsheng Men, Yuanyuan Wu, Ning Li, Mario R. Capecchi, Elizabeth C. Bryda, Sen Wu   +7 more
openalex   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Metal-organic polyhedra maintain the self-renewal of embryonic stem cells. [PDF]

Nat Commun
Wang R, Qi Y, Liu J, Li Y, An H, Wang H, Song J, Hu W, Wu S, Yu L, Chen Y, Xue X.   +11 more
europepmc   +1 more source

Novel vectors for homologous recombination strategies in mouse embryonic stem cells: An ES cell line expressing EGFP under control of the 5T4 promoter

, 2007
Flor M. Pérez-Campo, Helen Spencer, Rhoderick H. Elder, Peter L. Stern, Christopher M. Ward   +4 more
openalex   +2 more sources

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

SF3B1K700E mutation in human embryonic stem cells causes aberrant expression of immune-related genes. [PDF]

PLoS One
Dastpak M, Mimoso CA, Farshchian M, Paraggio CL, Leonard CE, Yin S, Chi B, Nassar KW, Rowe RG, Zhang J, Hou Z, Daley GQ, Adelman K, Reed R.   +13 more
europepmc   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Atf3 Deficiency Promotes Mesodermal Commitment and Enhances Endothelial Differentiation in Embryonic Stem Cells. [PDF]

Arterioscler Thromb Vasc Biol
Jiang Z, Su L, Chen C, He R, Jiang L, Shu Y, Dai D, Wu M, Guo A, Liu J, Liu S, Liu Z.   +11 more
europepmc   +1 more source

H3.3K122A results in a neomorphic phenotype in mouse embryonic stem cells [PDF]

Benjamin J. Patty, C. Diana Jordan, Santana M. Lardo, Kris Troy, Sarah J. Hainer   +4 more
openalex   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source