Results 101 to 110 of about 2,310 (177)

Embryotoxicity Hazard Assessment of Methylmercury and Chromium Using Embryonic Stem Cells

, 2007
The embryonic stem cell test (EST) has been scientifically validated (2001) as an in vitro embryotoxicity test, showing a good overall test accuracy of 78%.
STUMMANN Tina, BREMER Susanne, HARENG Lars, L. Hareng, S. Bremer, T.C. Stummann   +5 more
core   +1 more source

Omega-3 fatty acids differentially influences embryotoxicity in subtypes of preeclampsia

, 2020
Background: Early (EOP) and late onset (LOP) preeclampsia are two subtypes of preeclampsia. This study examines the effect of maternal omega-3 fatty acids and vitamin E supplementation in a rat model of preeclampsia.
Mayur Swamy, Sadhana Joshi, Anvita Kale, Vaishali Kasture, Surabhi Dalvi   +4 more
core   +1 more source

Passiflora edulis Seed Oil in an Experimental Zebrafish Model of Hyperglycemia During Embryogenesis: Evaluation of Free Glucose Modulation, Oxidative Stress, Antioxidant Gene Expression, and Developmental Safety

Molecules
Passiflora edulis seed oil (PESO) is a rich source of lipophilic bioactive compounds with potential to modulate oxidative stress and free glucose levels.
Elaine L. S. S. Mendonça, Felipe C. Silva, José W. A. C. Silva, Rafael L. B. Oliveira, Igor F. P. Silva, Henrique F. Goulart, Antônio E. G. Santana, João I. Soletti, Alane C. M. Oliveira, Marília O. F. Goulart, Jadriane A. Xavier   +10 more
doaj   +1 more source

Characterization of Synergistic Embryotoxicity of Nickel and Buprofezin in Zebrafish

, 2015
Multiple pollutants, usually at low levels, coexist and may interact in the environment. It is therefore important to analyze the toxicity of mixtures of coexisting chemicals to evaluate the potential ecological risk.
Wuyao Jia (1625146), Yang Yun (1461373), Guangke Li (1461379), Na Zhu (331131), Wei Yan (4327), Nan Sang (389836), Tingting Ku (1625149)   +6 more
core   +1 more source

Predictive biomarkers for embryotoxicity: A machine learning approach to mitigating multicollinearity in RNA-Seq

Multicollinearity, characterized by significant co-expression patterns among genes, often occurs in high-throughput expression data, potentially impacting the predictive model\u27s reliability.
Chan, Jireh Yi-Le, Ham, Onju, Kim, Sangyun, Jeong, Ji-Seong, Quah, Yixian, Yu, Wook-Joon, Lee, Seung-Jin, Jung, Soontag, Kim, Woojin, Park, Seung-Chun   +9 more
core   +1 more source

Embryotoxicity/teratogenicity study with isomaltulose (Palatinose R) in rats

, 1997
The embryotoxicity/teratogenicity of the natural sweetener isomaltulose (Palatinose®) was studied in Wistar rats. Groups of 24 mated females were fed diets containing isomaltulose at levels of 0, 2.5, 5 and 10% from day 0 to day 21 of pregnancy.
Lina, B.A.R., Smits-van Prooije, A.E., Waalkens-Berendsen, D.H.   +2 more
core  

Embryotoxicity Induced by Triclopyr in Zebrafish (Danio rerio) Early Life Stage

Toxics
Triclopyr, an auxin-like herbicide that is widely employed for managing weeds in food crops and pastures, has been identified in various environmental settings, particularly aquatic ecosystems.
Ítalo Bertoni, Bianca Camargo Penteado Sales, Cristina Viriato, Paloma Vitória Lima Peixoto, Lílian Cristina Pereira   +4 more
doaj   +1 more source

Antioxidants reduce reactive oxygen species but not embryotoxicity in the metabolic Danio rerio test (mDarT)

, 2017
: Mammalian liver microsomes are occasionally used as a metabolic activation system (MAS) to compensate for the low CYP-mediated bioactivation of drugs in zebrafish embryos, in the so-called mDarT.
Pype, Casper, Verbueken, Evy, Knapen, Dries, Casper Pype, Moayad A. Saad, Evy Verbueken, Steven J. Van Cruchten, Bars, Chlo\ue9, Saad, Moayad A., Chloé Bars, Van Cruchten, Steven J., Chris J. Van Ginneken, Van Ginneken, Chris J., Dries Knapen   +13 more
core   +1 more source

Predictive value of cell assays for developmental toxicity and embryotoxicity of conazole fungicides. [PDF]

, 2013
This paper evaluates in vivo predictability of a battery of in vitro tests covering developmental toxicity and embryotoxicity of five widely used conazole fungicides. The conazoles were investigated in the embryonic stem cell test, and data were compared
Nellemann, Christine Lydia, Hass, Ulla, Sørensen, Karin Dreisig, Vinggaard, Anne Marie, Taxvig, Camilla, Kjærstad, Mia Birkhøj   +5 more
core  

A comparative study of metal oxide nanoparticles embryotoxicity using the embryonic stem cell test

, 2013
Many in vitro studies demonstrated that metal oxide nanoparticles like zinc oxide and titanium dioxide are versatile platforms for industrial and biomedical applications.
Camaioni, A, Campagnolo, L, CAMAIONI, ANTONELLA, Vecchione, L, PIETROIUSTI, ANTONIO, Magrini, A, Massimiani, M, MAGRINI, ANDREA, Sifrani, L, Pietroiusti, A, CAMPAGNOLO, LUISA   +10 more
core   +1 more source