Results 111 to 120 of about 2,310 (177)

Determination of the embryotoxic effect of Metronidazole using an in ovo model

Revista Científica
Metronidazole is an imidazole group bactericidal antibiotic used against anaerobic bacteria and some protozoa. There is no detailed information about the embryotoxic effect of Metronidazole.
Muhittin Uslu, Rahmi Canbar, Mustafa Sedat Arslan, Harun Kızılay   +3 more
doaj   +1 more source

Polyhydroxy steroids isolated from starfish (Asterina pectinifera) and their embryotoxicity

Many marine organisms possess an essential capacity to produce secondary metabolites that exhibit toxic characteristics. A new polyhydroxy steroid, 24-methyl-5 alpha-cholestane-24(28)-ene-3 beta, 4 beta, 6 alpha, 7 alpha, 8, 15 beta, 16 beta, 26-octol-6 ...
Sun, Xueting, Lu, Zhen, Wang, Derui, Yan, Zhi, Li, Ke, Li, Xiaodong, Zhang, Ranran, Yin, Xiuli   +7 more
core   +1 more source

Development of an embryotoxicity test for Enchytraeus crypticus: the effect of Cd

The existing standard enchytraeid reproduction test (ERT) concerns the assessment of effects on survival and reproduction. In the present study we optimized and propose an embryotoxicity test using Enchytraeus crypticus. Cadmium (Cd) was used as a test
Gonçalves, Micael F. M., Bicho, Rita C., Rêma, Alexandra, Faustino, Augusto M. R., Soares, Amadeu M. V. M., Amorim, Mónica J. B.   +5 more
core   +1 more source

Biochemical and histopathological evaluation of the potential toxicity of Moxifloxacin in chicken embryos

Revista Científica
Moxifloxacin is a broad-spectrum fluoroquinolone antibiotic used in the treatment of acute bacterial sinusitis, community-acquired pneumonia, and chronic bronchitis.
Tugba Melike Parlak, Rahmi Canbar, Mehmet Tuzcu, Osman Dagar   +3 more
doaj  

Lysosomal cysteine proteinases and their role in visceral yolk sac mediated nutrition and embryotoxicity.

, 1994
The embryotoxicity of certain chemicals has been associated with an inhibition of protein degradation in the visceral yolk sac (VYS), an extraembryonic membrane responsible for embryonic amino acid supply prior to the formation of the functional placenta.
Ambroso, Jeffrey Lee
core  

Assaying Embryotoxicity in the Test Tube: Current Limitations of the Embryonic Stem Cell Test (EST) Challenging Its Applicability Domain

Critical Reviews in Toxicology, 2012
Testing for embryotoxicity in vitro is an attractive alternative to animal experimentation. The embryonic stem cell test (EST) is such a method, and it has been formally validated by the European Centre for the Validation of Alternative Methods. A number
Andreas Luch, Christian Riebeling, Horst Spielmann   +2 more
exaly   +2 more sources

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Locoweed Embryotoxicity in Rats

Clinical Toxicology, 1980
In an effort to develop a laboratory animal assay for locoweed (Astragalus lentiginosus and Astragalus wootoni) teratogenicity, different amounts of the plant were administered either in feed pellets or by gavage to rats. In preliminary experiments with A.
B K, Nelson, L F, James, R P, Sharma, C D, Cheney   +3 more
openaire   +2 more sources

Validation of an Embryotoxicity Assay

American Journal of Reproductive Immunology, 1995
PROBLEM: Culture of mouse blastocysts has served as a tool for identifying various embryotoxic factors in human serum. While inactivated, sera from recurrently aborting women inhibit mouse blastocyst development in vitro. Variation in results from individual serum samples has limited the usefulness of this assay in establishing a new classification of ...
R G, Roussev, J J, Stern, L P, Thorsell, E J, Thomason, C B, Coulam   +4 more
openaire   +2 more sources

Testing for Embryotoxicity

1980
No animal species exists with which the situation in man can be completely mimicked. This also holds true for non-human primates. With animal experiments only certain aspects of the whole complex situation can be analyzed. In order to achieve this successfully, animal species and experimental set-ups have to be chosen carefully to represent the ...
R, Bass, D, Neubert
openaire   +2 more sources

Embryotoxicity of Mirtazapine: A study using Chick Embryotoxicity Screening Test

Reproductive Toxicology, 2010
Mirtazapine is a new antidepressant used in last years, however experience with it during pregnancy is unsatisfactory on the present. Its wide therapeutic range and only little proved side effects may be an advantage for treatment during pregnancy. Aim of our study was to contribute to the knowledge on possible risks.For embryotoxicity testing we used ...
Eva, Manakova, Lucie, Hubickova, Jana, Kostalova, Zdena, Zemanova   +3 more
openaire   +2 more sources