Results 111 to 120 of about 4,236 (177)

A Novel Mutation Of The EMD Gene In A Family With Cardiac Conduction Abnormalities And A High Incidence Of Sudden Cardiac Death

Pharmacogenomics and Personalized Medicine, 2019
Demiao Kong,1,2,* Yi Zhan,3,* Canzhao Liu,4 Yerong Hu,1 Yangzhao Zhou,1,4 Jiawen Luo,1 Lu Gu,1 Xinmin Zhou,1 Zhiwei Zhang1,4 1Department of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China ...
Kong D, Zhan Y, Liu C, Hu Y, Zhou Y, Luo J, Gu L, Zhou X, Zhang Z   +8 more
doaj  

Emerin evaluation in Emery-Dreifuss muscular dystrophy patients

, 1997
The diagnosis of X-linked Emery-Dreifuss muscular dystrophy (EDMD) is now normally confirmed by genetic analysis of the recently discovered STA gene which codes for the protein emerin.
Toniolo D, Barresi R, Bione S, Mora, Di Blasi C, Bernasconi P, Cobianchi F, M, Cartegni L, Morandi L, Cornelio F   +10 more
core  

Emery–Dreifuss muscular dystrophy: a test case for precision medicine

The Application of Clinical Genetics, 2016
De-Ann M Pillers,1 Nicholas H Von Bergen21Division of Neonatology and Newborn Medicine, 2Division of Cardiology, Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, USAAbstract: Emery–Dreifuss muscular dystrophy (EDMD) is ...
Pillers DAM, Von Bergen NH
doaj  

The expression and role of the Lem-D proteins Ankle2, Emerin, Lemd2, and TMPO in triple-negative breast cancer cell growth

Frontiers in Oncology
BackgroundTriple-negative breast cancer (TNBC) is a sub-classification of breast carcinomas, which leads to poor survival outcomes for patients. TNBCs do not possess the hormone receptors that are frequently targeted as a therapeutic in other cancer ...
Maddison Rose, Joshua T. Burgess, Chee Man Cheong, Mark N. Adams, Parastoo Shahrouzi, Kenneth J. O’Byrne, Kenneth J. O’Byrne, Derek J. Richard, Emma Bolderson   +8 more
doaj   +1 more source

Additional file 2: of Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus

, 2019
(a) Representative western blot showing expression levels of NM1 in single and combined depletion of Lamin A/C and Emerin in DLD-1 cells. (b) Densitometric quantification of band intensities for NM1 in single and combined depletion of Lamin A/C and ...
Roopali Pradhan (6726713), Sushmitha Hegde (6726719), Devika Ranade (6726710), Muhunden Jayakrishnan (6726716), Kundan Sengupta (379275)   +4 more
core   +1 more source

FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity

Cell Reports
Summary: The mechanical environment generated through the adhesive interaction of endothelial cells (ECs) with the matrix controls nuclear tension, preventing aberrant gene synthesis and the transition from restrictive to leaky endothelium, a hallmark of
Md Zahid Akhter, Pascal Yazbeck, Mohammad Tauseef, Mumtaz Anwar, Faruk Hossen, Sayanti Datta, Vigneshwaran Vellingiri, Jagdish Chandra Joshi, Peter T. Toth, Nityanand Srivastava, Stephen Lenzini, Guangjin Zhou, James Lee, Mukesh K. Jain, Jae-Won Shin, Dolly Mehta   +15 more
doaj   +1 more source

The Use of Emerin-Null and EDMD-Causing Emerin Mutant Myogenic Progenitors to Elucidate the EDMD Mechanism

, 2020
Mutations in the gene encoding emerin (EMD) cause Emery-Dreifuss muscular dystrophy (EDMD1), an inherited disorder characterized by progressive skeletal muscle wasting, irregular heart rhythms and contractures of major tendons.
Iyer, Ashvin
core  

A Novel Emerin/Nesprin-3 Interaction Mediates Nuclear Size Changes Induced by Oncogenic KRAS in Pancreatic Cancer Cells. [PDF]

Mol Cell Biol
LaRue-Nolan KC, Flores LF, Vera RE, Sigafoos AN, Hilario Garcia L, Almada LL, Tader BR, Rodriguez-Quevedo MF, May DG, Marks DL, Roux KJ, Fernandez-Zapico ME.   +11 more
europepmc   +1 more source

Lamin B1 loss in human cardiomyocytes is associated with nuclear shape deformation in dilated cardiomyopathy. [PDF]

J Mol Cell Cardiol Plus
Ventimiglia LN, Zelezniak A, Dos Remedios CG, Lal S, Ehler E, De Nicola GF.   +5 more
europepmc   +1 more source

Nuclear envelope proteins in cancer: revisiting the significance of LEM-domain proteins. [PDF]

Front Cell Dev Biol
Jobe A, Mirza S, Vijayan R.
europepmc   +1 more source