Results 121 to 130 of about 6,334 (202)

The expression and role of the Lem-D proteins Ankle2, Emerin, Lemd2, and TMPO in triple-negative breast cancer cell growth

Frontiers in Oncology
BackgroundTriple-negative breast cancer (TNBC) is a sub-classification of breast carcinomas, which leads to poor survival outcomes for patients. TNBCs do not possess the hormone receptors that are frequently targeted as a therapeutic in other cancer ...
Maddison Rose, Joshua T. Burgess, Chee Man Cheong, Mark N. Adams, Parastoo Shahrouzi, Kenneth J. O’Byrne, Kenneth J. O’Byrne, Derek J. Richard, Emma Bolderson   +8 more
doaj   +1 more source

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling [PDF]

, 2017
Lamins are intermediate filament proteins that assemble into a meshwork underneath the inner nuclear membrane, the nuclear lamina. Mutations in the LMNA gene, encoding lamins A and C, cause a variety of diseases collectively called laminopathies.
Dialynas, George, Herrmann, Harald, Isermann, Philipp, Jaalouk, Diana E., Lammerding, Jan, Lombardi, Maria L., Mauermann, Monika, Wallrath, Lori L., Zwerger, Monika   +8 more
core  

Actin and Rho GTPases in herpesvirus biology [PDF]

, 2007
ENQUIST, LW, Favoreel, Herman, FEIERBACH, B   +2 more
core   +1 more source

Proteome analysis of developing mice diastema region [PDF]

BMB Reports, 2012
Different from humans, who have a continuous dentition ofteeth, mice have only three molars and one incisor separatedby a toothless region called the diastema in the hemimandibular arch. Although tooth buds form in the embryonicdiastema, they regress and
Young-Mi Chae1, Young-Joo Jin1, Hyeng-Soo Kim2, Gi-Jeong Gwon1, Wern-Joo Sohn1,2, Sung-Hyun Kim3, Myoung-Ok Kim4, Sanggyu Lee2, Jo-Young Suh5 & Jae-Young Kim1*
doaj  

FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity

Cell Reports
Summary: The mechanical environment generated through the adhesive interaction of endothelial cells (ECs) with the matrix controls nuclear tension, preventing aberrant gene synthesis and the transition from restrictive to leaky endothelium, a hallmark of
Md Zahid Akhter, Pascal Yazbeck, Mohammad Tauseef, Mumtaz Anwar, Faruk Hossen, Sayanti Datta, Vigneshwaran Vellingiri, Jagdish Chandra Joshi, Peter T. Toth, Nityanand Srivastava, Stephen Lenzini, Guangjin Zhou, James Lee, Mukesh K. Jain, Jae-Won Shin, Dolly Mehta   +15 more
doaj   +1 more source

Update of Emerinopathies’ clinical-genetic spectrum: the French network experience [PDF]

, 2015
France Leturcq, Rabah Ben Yaou
core   +1 more source

Chromatin states and nuclear organization in development — a view from the nuclear lamina [PDF]

, 2015

core   +1 more source

A-type lamins anchor emerin at the inner nuclear membrane via two independent binding sites. [PDF]

J Biol Chem
Odell J, Nedza K, Lammerding J.
europepmc   +1 more source

LEM-Domain-Containing Inner Nuclear Membrane Proteins: Emerging Regulators of Intranuclear Signaling. [PDF]

Int J Mol Sci
Lee B, Lee H, Shim J.
europepmc   +1 more source

Variable A-type lamin expression in Merkel cell carcinoma cell lines and its association with nuclear integrity. [PDF]

Sci Rep
Stiekema M, van Gorp C, Macamo A, Hausen AZ, van Zandvoort MAMJ, Ramaekers FCS, Broers JLV.   +6 more
europepmc   +1 more source