Results 161 to 170 of about 3,273,294 (390)
Enantioselective Synthesis of Cyclobutylboronates via a Copper-Catalyzed Desymmetrization Approach.
Angewandte Chemie, 2016 The first catalytic enantioselective synthesis of cyclobutylboronates, by using a chiral copper(I) complex, is reported. A broad variety of cyclobutanes have been prepared with consistently high levels of diastereo- and enantiocontrol.
Manuel Guisán-Ceinos +3 more
semanticscholar +1 more source
Enantioselective Total Synthesis of (−)‐Blennolide A
Chemistry – A European Journal, 2013 AbstractBlennolide A can be synthesized through an enantioselective domino‐Wacker/carbonylation/methoxylation reaction of 7 a with 96 % ee and an enantioselective Wacker oxidation of 7 b with 89 % ee. Further transformations led to the α,β‐unsaturated ester (E)‐17, which was subjected to a highly selective Michael addition, introducing a methyl group ...
Tietze, Lutz Friedjan +4 more
openaire +4 more sources
Angewandte Chemie, EarlyView.The synthesis of cyanocyclopropanes is achieved via asymmetric nitrogen insertion into prochiral cyclobutanones. Key mechanistic steps involve an organocatalyzed asymmetric condensation followed by chirality transfer via an intercepted Neber rearrangement.
Marlene Arnold +4 more
wiley +2 more sources
Enantioselective Total Synthesis of (+)-Salvileucalin B [PDF]
, 2011 An enantioselective total synthesis of the diterpenoid natural product (+)-salvileucalin B is reported. Key findings include a copper-catalyzed arene cyclopropanation reaction to provide the unusual norcaradiene core and a reversible retro ...
Levin, Sergiy +2 more
core +1 more source
Enantioselective manipulation of chiral nanoparticles using optical tweezers [PDF]
arXiv, 2019 We put forward an enantioselective method for chiral nanoparticles using optical tweezers. We demonstrate that the optical trapping force in a typical, realistic optical tweezing setup with circularly-polarized trapping beams is sensitive to the chirality of core-shell nanoparticles, allowing for efficient enantioselection.
arxiv
Enantioconvergent Deacylative Functionalization toward α‐Quaternary Nitriles
Angewandte Chemie, EarlyView.An enantioconvergent quaternary‐to‐quaternary synthesis of α‐chiral nitriles has been enabled. By replacing the acyl group with a variety of allyl, propargyl, and benzyl motifs, the functional group swap can convert easily available β‐ketonitriles to assorted quaternary stereocenters en route to bioactive molecules of broad interests.
Minghao Zhang, Zhongxing Huang
wiley +2 more sources
Synthetic Studies Directed Toward Streptenol D: Enantioselective Preparation of the 3,5-diacetoxy-6\u3cem\u3eE\u3c/em\u3e,8\u3cem\u3eE\u3c/em\u3e-decadiene Segment [PDF]
, 1998 The enantioselective preparation of 2-(3′R,5′R-diacetoxy-6E,8E-decadienyl)-1,3-dioxane, (+)-13, is described. This synthesis of the skeleton of streptenol D utilizes the ability of a diene-complexed (tricarbonyl)iron unit to serve as a protecting and ...
Dasgupta, Bireshwar, Donaldson, William
core +1 more source
Enantioselective Synthesis of Allenes by Catalytic Traceless Petasis Reactions.
Journal of the American Chemical Society, 2017 Allenes are useful functional groups in synthesis as a result of their inherent chemical properties and established reactivity patterns. One property of chemical bonding renders 1,3-substituted allenes chiral, making them attractive targets for ...
Yao-Chen Jiang +3 more
semanticscholar +1 more source
Size‐Programmable Matteson‐Type Annulation: Construction of Spirocycles from Simple Cyclic Ketones
Angewandte Chemie, EarlyView.An iterative boron‐homologation approach is developed to enable programmable syntheses of various carbocycles with different sizes stereoselectively from simple precursors. This method utilizes an electron‐withdrawing group (EWG) as a handle to enable intramolecular Matteson‐type couplings, leading to diastereoselective and enantioselective ring ...
Woohyun Jo +4 more
wiley +2 more sources
Angewandte Chemie, 2017 The catalytic enantioselective synthesis of isoindolinones was achieved through the condensation of 2-acyl-benzaldehydes and anilines. In the presence of 1 mol % of a chiral phosphoric acid catalyst, reactions reach completion within 10 min and provide ...
C. Min, Ying-Rui Lin, D. Seidel
semanticscholar +1 more source