Results 161 to 170 of about 3,272,143 (363)

Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Five-, Six-, and Seven-Membered β-Substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters [PDF]

, 2011
The first enantioselective Pd-catalyzed construction of all-carbon quaternary stereocenters via 1,4-addition of arylboronic acids to β-substituted cyclic enones is reported. Reaction of a wide range of arylboronic acids and cyclic enones using a catalyst
Gatti, Michele, Holder, Jeffrey C., Kikushima, Kotaro, Stoltz, Brian M.   +3 more
core   +1 more source

Rapid Access to an Enantioenriched Spiro Bisindole Directly from Indole and Acetone

Angewandte Chemie, EarlyView.
A catalytic enantioselective one‐pot “self‐assembly” strategy was developed for the exceedingly convenient access to a spiro bisindole directly from indole and acetone. The obtained enantiopure C2‐symmetric bisindole showed exceptional performance as a chiral backbone of diverse effective catalysts or ligands. Abstract Disclosed here is a “one‐pot self‐
Jing‐Yi Wang, Jie Lin, Chaoshen Zhang, Jianwei Sun   +3 more
wiley   +2 more sources

Catalytic Asymmetric Cyclizative Rearrangement of Anilines and Vicinal Diketones to Access 2,2‐Disubstituted Indolin‐3‐ones

Advanced Science
The efficient synthesis of chiral 2,2‐disubstituted indolin‐3‐ones is of great importance due to its significant synthetic and biological applications. However, catalytic enantioselective methods for de novo synthesis of such heterocycles remain scarce ...
Rui Quan, Xing‐Zi Li, Zi‐Qi Wang, Yu‐Ping He, Hua Wu   +4 more
doaj   +1 more source

Organocatalytic stereodivergent synthesis of β,β-disubstituted-α-aminoacids [PDF]

, 2017
In this work, we present an organocatalytic stereodivergent synthesis of β,β-disubstituted-α-aminoacids using arylidene azlactones as starting materials.
Martinelli, Ada
core  

Total Synthesis of Isodaphlongamine H by Iridium‐Catalyzed Reductive [3 + 2] Cycloaddition of N‐Hydroxylactam

Angewandte Chemie, EarlyView.
The total synthesis of isodaphlongamine H was accomplished by a lactam strategy. This strategy started with alkylation and N‐oxidation of a readily available chiral lactam. For the key functionalization of the amide carbonyl, an iridium‐catalyzed reductive [3 + 2] cycloaddition of the N‐hydroxylactam afforded the tricyclic isoxazolidine, which was ...
Sora Iwamoto, Reki Nakano, Keiji Sasaki, Shoichiro Kobayashi, Yuki Taira, Koya Takei, Reiji Kawakita, Ayako Tokuyama, Haruto Nakamura, Manato Tomoike, Ryota Kawahara, Akari Murase, Siro Simizu, Noritaka Chida, Toshitaka Okamura, Takaaki Sato   +15 more
wiley   +2 more sources

Chemoenzymatic enantioselective synthesis of baclofen [PDF]

, 1994
Robert Chênevert, Michel Desjardins
openalex   +1 more source

Mirror symmetry breaking with limited enantioselective autocatalysis and temperature gradients: a stability survey

, 2012
We analyze limited enantioselective (LES) autocatalysis in a temperature gradient and with internal flow/recycling of hot and cold material. Microreversibility forbids broken mirror symmetry for LES in the presence of a temperature gradient alone.
Blanco, Celia, Crusats, Joaquim, El-Hachemi, Zoubir, Hochberg, David, Moyano, Albert, Ribó, Josep M.   +5 more
core   +1 more source

Iridium‐Catalyzed Enantioselective Intramolecular Hydroarylation of Allenes: Formal Synthesis of (+)‐Rhazinilam

Angewandte Chemie, EarlyView.
A highly enantioselective iridium‐catalyzed hydroarylation of allene‐tethered pyrroles and indoles that provides access to relevant heterocyclic systems bearing vinyl‐substituted 3ry or 4ry stereocenters is reported. Its synthetic potential was exemplified with a very short, highly enantioselective formal synthesis of (+)‐Rhazinilam, whereas DFT ...
Andrés Arribas, Alejandro Rey, Martín Calvelo, José L. Mascareñas, Fernando López   +4 more
wiley   +2 more sources

Enantioselective Catalysis for Agrochemicals: The Case History of the DUAL MAGNUM® Herbicide

CHIMIA, 1997
The use of enantioselective catalytic methods for the technical preparation of chiral agrochemicals is illustrated by the case history of the herbicide (S)-merolachlor (trade name DUAL MAGNUM®).
Hans-Ulrich Blaser, Felix Spindler
doaj   +2 more sources

Asymmetric 1,4-additions to γ-menthyloxybutenolides. (part II)1 enantioselective synthesis of lignan type compounds. [PDF]

, 1991
Johan F. G. A. Jansen, Christoph Jansen, B.L. Feringa   +2 more
openalex   +1 more source