Results 181 to 190 of about 3,272,143 (363)

An Enantioselective Synthesis of 1-(a-Hydroxyalkyl)-1,2,3,4-tetrahydroisoquinolines through Optically Active N-Oxaacyliminium Ion Intermediates

, 1985
Shinzo Kano, Yoko Yuasa, Shiroshi Shibuya   +2 more
openalex   +1 more source

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

Angewandte Chemie, EarlyView.
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Gaurav P. Kudalkar, Florian Leidner, Nivesh Kumar, Jared L. Hass, Peter Madzelan, Douglas R. Powell, Victor W. Day, Pierre Le Magueres, Joseph D. Ferrara, Lee M. Daniels, Akihito Yamano, Sho Ito, Wei Niu, Helmut Grubmüller, Mark A. Wilson, David B. Berkowitz   +15 more
wiley   +2 more sources

Asymmetric Syntheses via Heterocyclic Intermediates; XVII¹. Enantioselective Synthesis of (R)-α-Methyl-S-benzylcysteine Methyl Ester and (R)-α-Methyl-S-t-butylcysteine Methyl Ester Using L-Valine as Chiral Auxiliary Reagent

, 1983
Ulrich Groth, Ulrich Schöllkopf
openalex   +2 more sources

Notizen: Enantioselective Catalysis, 101 [1] Synthesis and Coordination Properties of (3′S,4′S)-(+)-1,2-Bis(3′,4′-dimethoxyphospholano)benzene, a N ew Chiral Diphosphane [PDF]

, 1996
Henri Brunner, Gemma Net
openalex   +1 more source

Asymmetric .ALPHA.-substituted phenethylamines. II. The enantioselective synthesis of 1-aryl-2-phenylethylamines from L- and D-amino acids by means of 1,3-asymmetric induction.

, 1983
Yuji Suzuki, Hiroshi Takahashi
openalex   +2 more sources

A Convergent, Enantioselective Total Synthesis of Hapalosin: A Drug with Multidrug‐Resistance Reversing Activity [PDF]

, 1996
Arun K. Ghosh, Wenming Liu, Yibo Xu, Zhidong Chen   +3 more
openalex   +1 more source

An Approach to the Enantioselective Synthesis of 2-Azabicyclo[2.2.1]hept-5-en-3-one

, 1988
Franco Fernández, Eugenio Uriarte, Olga Caamaño, A. EIRIN, Generosa Gómez   +4 more
openalex   +1 more source

Synthetic studies on spiroketal natural products. II. An enantioselective synthesis of (R)- and (S)-1,7-dioxaspiro[5.5]undecane.

, 1988
C. IWATA, Masahiro Fujita, Toshio Kuroki, Kohji Hattori, Shuji Uchida, Takeshi Imanishi   +5 more
openalex   +2 more sources

Enantioselective total synthesis of (−)-α-kainic acid [PDF]

, 1998
Mario D. Bachi, Artem Melman
openalex   +1 more source

Enantioselective synthesis of (−)-methyl 5-lactylshikimate lactone

, 1990
Vimudha Muralidharan, Harold B. Wood, Bruce Ganem   +2 more
openalex   +1 more source