Enantioselective Total Synthesis of (−)‐Diversonol
Chemistry – A European Journal, 2013 AbstractFor the synthesis of (−)‐diversonol (ent‐1), an enantioselective domino‐Wacker/carbonylation/methoxylation reaction and an enantioselective Wacker oxidation were used to give the chroman in high yield and 96 % and 93 % ee, respectively. Dihydroxylation at the vinyl moiety using the Sharpless procedure and a Wittig–Horner reaction followed by ...
Tietze, Lutz Friedjan +5 more
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Organocatalytic atroposelective construction of axially chiral arylquinones
Nature Communications, 2019 Axially chiral compounds have widespread use in asymmetric catalysis. Here, the authors disclose a highly enantioselective synthesis of axially chiral o-naphthoquinones by chiral phosphoric acid catalysis and central-to-axial chirality conversion.
Shuai Zhu +8 more
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Enantioselective Synthesis of Sulfinamidines via Asymmetric Nitrogen Transfer from N−H Oxaziridines to Sulfenamides [PDF]
Sulfinamidines are promising aza-SIV chiral building blocks in asymmetric synthesis and drug discovery. However, no report has documented their enantioselective synthesis.
Fimm, Marc, Saito, Fumito
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Enantioselective synthesis of (R)‐ and (S)‐2‐methyl‐[3,3,2‐2H3] alanines [PDF]
, 1986 Pullachipatti K. Subramanian +1 more
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Asymmetric total synthesis of smyrindiol employing an organocatalytic aldol key step
Beilstein Journal of Organic Chemistry, 2012 The first organocatalytic asymmetric synthesis of smyrindiol, by using an (S)-proline catalyzed enantioselective intramolecular aldol reaction as the key step, is described. Smyrindiol was synthesized from commercially available 2,4-dihydroxybenzaldehyde
Dieter Enders +3 more
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Enantioselective Total Synthesis of (—)-Acetylaranotin, a Dihydrooxepine Epidithiodiketopiperazine [PDF]
, 2012 The first total synthesis of the dihydrooxepine-containing epidithiodiketopiperazine (ETP) (−)-acetylaranotin (1) is reported. The key steps of the synthesis include an enantioselective azomethine ylide (1,3)-dipolar cycloaddition reaction to set the ...
Codelli, Julian A. +2 more
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Enantioselective Catalysis for Agrochemicals: The Case History of the DUAL MAGNUM® Herbicide
CHIMIA, 1997 The use of enantioselective catalytic methods for the technical preparation of chiral agrochemicals is illustrated by the case history of the herbicide (S)-merolachlor (trade name DUAL MAGNUM®).
Hans-Ulrich Blaser, Felix Spindler
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Advanced ScienceThe efficient synthesis of chiral 2,2‐disubstituted indolin‐3‐ones is of great importance due to its significant synthetic and biological applications. However, catalytic enantioselective methods for de novo synthesis of such heterocycles remain scarce ...
Rui Quan +4 more
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Beilstein Journal of Organic Chemistry, 2012 Enantioselective organocatalysis has become a field of central importance within asymmetric chemical synthesis and appears to be efficient approach toward the construction of complex chiral molecules from simple achiral materials in one-pot ...
Chittaranjan Bhanja +3 more
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Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Five-, Six-, and Seven-Membered β-Substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters [PDF]
, 2011 The first enantioselective Pd-catalyzed construction of all-carbon quaternary stereocenters via 1,4-addition of arylboronic acids to β-substituted cyclic enones is reported. Reaction of a wide range of arylboronic acids and cyclic enones using a catalyst
Gatti, Michele +3 more
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