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Enantioselective Synthesis of (−)-Dysiherbaine
Organic Letters, 2015Dysiherbaine, a natural product isolated from the Marine sponge Dysidea herbacea, has been shown to be a selective agonist of non-NMDA type glutamate receptors, kainate receptors. An enantioselective synthesis of dysiherbaine is reported. Metathesis of the diene followed by conversion of the resulting alkene to the amino alcohol and addition of the ...
Ha, Do +3 more
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Enantioselective Synthesis of Paraconic Acids.
ChemInform, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Rakeshwar B, Chhor +5 more
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Enantioselective Total Synthesis of (‐)‐Microcarpalide.
ChemInform, 2005Abstract The enantioselective total synthesis of the actin-targeting metabolite (−)-microcarpalide is described. Key steps include ring-closing metathesis (RCM) for the final construction of the 10-membered lactone framework and stereoselective homologation of boronic esters for the insertion of all stereocentres with the desired absolute ...
DAVOLI, Paolo +4 more
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Enantioselective Total Synthesis of Cylindramide.
ChemInform, 2005Key steps in the convergent enantioselective synthesis of the cytotoxic natural product cylindramide are tandem Michael addn./electrophilic trapping reactions, Sonogashira coupling, Julia-Kocienski olefination, and macrocyclization. For example, the Sonogashira coupling of pentalene I with iodoacrylate II followed by Julia-Kocienski olefination with ...
Nicolai, Cramer +4 more
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Enantioselective Total Synthesis of (+)-Neosymbioimine
Organic Letters, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Georgy N, Varseev, Martin E, Maier
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Enantioselective Total Synthesis of Borrelidin
Journal of the American Chemical Society, 2003The first total synthesis of the natural product borrelidin is described. The propionate fragment of the molecule was concisely synthesized through catalytic enantioselective reductive aldol reactions, a catalytic Negishi coupling, and a catalytic directed hydrogenation.
Matthew O, Duffey +2 more
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Enantioselective synthesis of aroylalanine derivatives
Tetrahedron Letters, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Barry Lygo, Benjamin I. Andrews
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Enantioselective synthesis of (−)-galantinic acid
Tetrahedron Letters, 2004Abstract An efficient enantioselective synthesis of (−)-galantinic acid 1 , a non-proteogenic amino acid is described using Sharpless asymmetric epoxidation, dihydroxylation and the regioselective nucleophilic opening of a cyclic sulfite as the key steps.
Satyendra Kumar Pandey +2 more
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