Results 91 to 100 of about 39,817 (294)

Proof of enantioselectivity in a multilayer with a strong exciton polariton coupling and through asymmetric polarization [PDF]

arXiv, 2023
The plasmonic investigation involves activating a multilayer consisting of silver, platinum, silica, and silicon. Hybrid waveguide and surface plasmon polariton modes define the device plasmonic activity. The presence of micrometric features on the multilayer surface facilitates the formation of the waveguide mode.
arxiv  

Asymmetric Hydrogenation in Water by a Rhodium Complex of Sulfonated 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (binap) [PDF]

, 1993
The synthesis of sulfonated 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl (binap) is reported; a rhodium complex of this ligand is the first to perform asymmetric hydrogenation in neat water with optical yields as high as those obtained in nonaqueous ...
Davis, Mark E., Wan, Kam-to
core   +1 more source

Photochemical Preparation of (Aza−)Indolines: Diastereoselective Synthesis and Polarity Reversal Strategy

Advanced Synthesis &Catalysis, EarlyView.
Abstract Herein, we present the first light‐mediated, diastereoselective de novo synthesis for 2,3‐substituted indolines, a privileged scaffold in pharmaceuticals. The protocol was tested with various aryl and alkyl groups, maintaining high yields up to 85% across different substituents.
Julian J. Melder, Maxi L. Heldner, Julia Svetličić, Abdinasir Adow, Frank Rominger, Matthias Rudolph, Günter Helmchen, A. Stephen K. Hashmi   +7 more
wiley   +1 more source

Semi-rational engineering of a thermostable aldo–keto reductase from Thermotoga maritima for synthesis of enantiopure ethyl-2-hydroxy-4-phenylbutyrate (EHPB)

Scientific Reports, 2017
A novel aldo-keto reductase Tm1743 characterized from Thermotoga maritima was explored as an effective biocatalyst in chiral alcohol production. Natural Tm1743 catalyzes asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate (EOPB) at high efficiency, but ...
Zhiguo Wang, Shuo Zhou, Shuangling Zhang, Sa Zhang, Fangmeng Zhu, Xiaolu Jin, Zhenming Chen, Xiaoling Xu   +7 more
doaj   +1 more source

Recent Developments in Radical Mediated Synthesis of Organostannanes.

Advanced Synthesis &Catalysis, EarlyView.
Abstract The present review aims to provide an overview of the recent developments in the preparation of aryl‐ or alkenyl stannanes via carbon‐ and tin‐centered radicals enabling chemists to synthesize organostannyl derivatives with high efficiency and under mild conditions.
Qianhang Ren, Adrian Luguera Ruiz, Maurizio Fagnoni, Stefano Protti, Di Qiu   +4 more
wiley   +1 more source

Enantioselective Evans-Tishchenko Reduction of b-Hydroxyketone Catalyzed by Lithium Binaphtholate

Molecules, 2011
Lithium diphenylbinaphtholate catalyzed the enantioselective Evans-Tishchenko reduction of achiral b-hydroxyketones to afford monoacyl-protected 1,3-diols with high stereoselectivities.
Makoto Nakajima, Tomonori Ichibakase, Masato Nakatsu   +2 more
doaj   +1 more source

The effect of alcohol on the performance of lipase-immobilized enzymatic membrane reactor for esterification of (R,S)-ketoprofen [PDF]

, 2006
The effect of alcohols on the performance of lipase-immobilized enzymatic membrane reactor (EMR) for enantioselective esterification of (R,S)-ketoprofen has been studied. In this work, mixed solvent medium was used and the (R)-ketoprofen was reacted with
Bhatia, Subhash, Chuan Fu, Kian, Harun @ Kamaruddin, Azlina, Ong, Ai Lien   +3 more
core  

Development of Photo‐Biocatalytic Redox System for Asymmetric Synthesis of Optically Active Amines Using Blue Light and Transaminases. A Case Study Toward Mavacamten

Advanced Synthesis &Catalysis, EarlyView.
Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos, Aleksandra Rudzka, Anna Hoser, Tamara Reiter, Wolfgang Kroutil, Paweł Borowiecki   +5 more
wiley   +1 more source

A Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality [PDF]

, 2018
A highly diastereo- and enantioselective, scalable Pd-catalyzed dynamic kinetic asymmetric Heck reaction of heterobiaryl sulfonates with electron-rich olefins is described.
Carmona, José A., Fernández Fernández, Rosario Fátima, Gómez-Bengoa, Enrique, Hornillos, Valentín, Iglesias Sigüenza, Francisco Javier, Lassaletta, José M., Ramírez López, Pedro, Ros Lao, Abel   +7 more
core   +29 more sources

Enantioselective Desymmetrization of FTY720

Chemical and Pharmaceutical Bulletin, 2014
A method for enantioselective desymmetrization of N-Ac and N-Boc-FTY720 by nonenzymatic asymmetric acylation was developed. Effective enantioselective monobenzoylation using benzoyl chloride in the presence of the tetraphenylbisoxazoline (L2)-CuCl2 complex gave the desired products 3a and 3b in 52-62% yield with 64% ee.
Shoko Kikkawa, Yuka Uchida, Yuusaku Yokoyama, Maiko Hamada, Isao Azumaya, Hidemasa Hikawa   +5 more
openaire   +4 more sources