Enantioselective Synthesis of (−)-Acetylapoaranotin
Organic Letters, 2017 The first enantioselective total synthesis of the epipolythiodiketopiperazine (ETP) natural product (-)-acetylapoaranotin (3) is reported. The concise synthesis was enabled by an eight-step synthesis of a key cyclohexadienol-containing amino ester building block.
Haoxuan Wang +5 more
openaire +5 more sources
Directed enzyme evolution: climbing fitness peaks one amino acid at a time [PDF]
, 2009 Directed evolution can generate a remarkable range of new enzyme properties. Alternate substrate specificities and reaction selectivities are readily accessible in enzymes from families that are naturally functionally diverse.
Arnold, Frances H., Tracewell, Cara A.
core +2 more sources
Green Synthesis and Catalysis, 2021 Biocatalysts with tailor-made or controllable stereoselectivity are valuable and highly desired in the precision synthesis of chiral compounds. Most lipases display excellent (R)-enantioselectivity for various sec-alcohols.
Danyang Li +5 more
doaj
Enantioselective optical forces in gain-functionalized single core-shell chiral nanoparticles [PDF]
arXiv, 2022 We propose a gain-assisted enantioselective scheme in dye-doped chiral particles, demonstrating optical pulling and pushing forces that can be tuned using externally controllable parameters. By controlling the concentration of dye molecules and pumping rate, we achieve all-optical chiral resolution of racemic mixtures and enantioselection of small ...
arxiv
Modification of chiral dimethyl tartrate through transesterification : immobilisation on POSS and enantioselectivity reversion in Sharpless asymmetric epoxidation [PDF]
, 2010 Modification of dimethyl tartrate has been investigated through transesterification with aminoalcohols to provide reactive functionalities for the covalent bonding of chiral tartrate to polyhedral oligomeric silsesquioxanes.
García, Rafael A. +4 more
core +1 more source
Organocatalyzed Enantioselective Fluorocyclizations
Angewandte Chemie International Edition, 2011 AbstractTwo different halogenation procedures including both (DHQ)2‐PHAL as the enantioselective agent are developed for the preparation of fluorinated heterocyclic scaffolds which are obtained as exclusive cis isomers.
Lozano, O +8 more
openaire +4 more sources
Enantioselection and chiral sorting of single microspheres using optical pulling forces [PDF]
arXiv, 2021 We put forward a novel, twofold scheme that enables at the same time all-optical enantioselection and sorting of single multipolar chiral microspheres based on optical pulling forces exerted by two non-collinear, nonstructured, circularly-polarized light sources.
arxiv
Controlled enantioselective orientation of chiral molecules with an optical centrifuge [PDF]
Phys. Rev. Lett. 122, 223201 (2019), 2019 We report on the first experimental demonstration of enantioselective rotational control of chiral molecules with a laser field. In our experiments, two enantiomers of propylene oxide are brought to accelerated unidirectional rotation by means of an optical centrifuge.
arxiv +1 more source
Observation of persistent orientation of chiral molecules by laser field with twisted polarization [PDF]
Phys. Rev. A 101, 021403 (2020), 2019 Molecular chirality is an omnipresent phenomenon of fundamental significance in physics, chemistry and biology. For this reason, search for novel techniques for enantioselective control, detection and separation of chiral molecules is of particular importance.
arxiv +1 more source
Synthesis and enantiomeric recognition studies of a novel 5,5-dioxophenothiazine-1,9 bis(thiourea) containing glucopyranosyl groups [PDF]
, 2013 A novel optically active 5,5-dioxophenothiazine-1,9 bis(thiourea) containing glucopyranosyl groups was synthesized and its enantiomeric recognition properties were examined towards the enantiomers of tetrabutylammonium salts of chiral α-hydroxy and N ...
Baranyai, Péter +6 more
core +1 more source