Results 1 to 10 of about 71,203 (273)
The Microbiome and Gut Endocannabinoid System in the Regulation of Stress Responses and Metabolism
Frontiers in Cellular Neuroscience, 2022 The endocannabinoid system, with its receptors and ligands, is present in the gut epithelium and enteroendocrine cells, and is able to modulate brain functions, both indirectly through circulating gut-derived factors and directly through the vagus nerve,
Raj Kamal Srivastava +3 more
doaj +2 more sources
Role of the Endocannabinoid System in the Adipose Tissue with Focus on Energy Metabolism
Cells, 2021 The endocannabinoid system is involved in a wide range of processes including the control of energy acquisition and expenditure. Endocannabinoids and their receptors are present in the central nervous system but also in peripheral tissues, notably the ...
Volatiana Rakotoarivelo +2 more
doaj +2 more sources
Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]
, 2012 BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen +8 more
core +12 more sources
Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years
Pharmacological Reviews, 2023 The cannabis derivative marijuana is the most widely used recreational drug in the Western world and is consumed by an estimated 83 million individuals (∼3% of the world population).
M. Maccarrone +9 more
semanticscholar +1 more source
Frontiers in Aging Neuroscience, 2022 N-oleoylglycine (OlGly) is a lipid mediator that belongs to the expanded version of the endocannabinoid (eCB) system, the endocannabinoidome (eCBome), which has recently gained increasing attention from the scientific community for its protective effects
Anna Lauritano +9 more
doaj +1 more source
Biomolecules, 2022 Acute respiratory distress syndrome (ARDS) is a serious inflammatory lung disorder and a complication of SARS-CoV-2 infection. In patients with severe SARS-CoV-2 infection, the transition to ARDS is principally due to the occurrence of a cytokine storm ...
Aniello Schiano Moriello +8 more
doaj +1 more source
Cells, 2021 Bone is a highly complex and metabolically active tissue undergoing a continuous remodeling process, which endures throughout life. A complex cell-signaling system that plays role in regulating different physiological processes, including bone remodeling,
Magdalena Kostrzewa +6 more
doaj +1 more source
The Endocannabinoid System and Physical Exercise
International Journal of Molecular Sciences, 2023 The endocannabinoid system (ECS) is involved in various processes, including brain plasticity, learning and memory, neuronal development, nociception, inflammation, appetite regulation, digestion, metabolism, energy balance, motility, and regulation of ...
D. Matei +6 more
semanticscholar +1 more source
The Endocannabinoid System: A Bridge between Alzheimer’s Disease and Gut Microbiota
Life, 2021 Alzheimer’s disease (AD) is a neurodegenerative disease that progresses from mild cognitive impairment to severe dementia over time. The main clinical hallmarks of the disease (e.g., beta-amyloid plaques and neurofibrillary tangles) begin during ...
Tiziana Bisogno +2 more
doaj +1 more source
The Endocannabinoid System: A Potential Target for the Treatment of Various Diseases
International Journal of Molecular Sciences, 2021 The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a balance in internal environment (temperature, mood, and immune system) and energy input and output in living, biological systems.
H. Lowe +4 more
semanticscholar +1 more source