Results 21 to 30 of about 26,170 (225)

Endocannabinoid system in neurodegenerative disorders [PDF]

open access: yesJournal of Neurochemistry, 2017
AbstractMost neurodegenerative disorders (NDDs) are characterized by cognitive impairment and other neurological defects. The definite cause of and pathways underlying the progression of theseNDDs are not well‐defined. Several mechanisms have been proposed to contribute to the development ofNDDs.
Balapal S. Basavarajappa   +3 more
openaire   +3 more sources

The Endocannabinoid System and Cannabidiol: Past, Present, and Prospective for Cardiovascular Diseases

open access: yesPharmaceuticals, 2021
In the past, cannabis was commonly associated with mysticism and illegality. Fortunately, in recent years perspectives and discourses have changed. More prominence has been given to the rigorous scientific effort that led to the discovery of cannabis ...
Martina Rabino   +5 more
doaj   +1 more source

Mediterranean Diet and Neurodegenerative Diseases: The Neglected Role of Nutrition in the Modulation of the Endocannabinoid System

open access: yesBiomolecules, 2021
Neurodegenerative disorders are a widespread cause of morbidity and mortality worldwide, characterized by neuroinflammation, oxidative stress and neuronal depletion.
Federica Armeli   +4 more
doaj   +1 more source

Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats

open access: yesBiology of Sex Differences, 2021
Background Several chronic pain disorders, such as migraine and fibromyalgia, have an increased prevalence in the female population. The underlying mechanisms of this sex-biased prevalence have yet to be thoroughly documented, but could be related to ...
Aidan Levine   +8 more
doaj   +1 more source

Endocannabinoid system: Potential novel targets for treatment of schizophrenia

open access: yesNeurobiology of Disease, 2013
Accumulating epidemiological evidences suggest that cannabis use during adolescence is a potential environmental risk for the development of psychosis, including schizophrenia.
Atsushi Saito   +4 more
doaj   +1 more source

Modulation of the Endocannabinoid System as a Potential Anticancer Strategy

open access: yesFrontiers in Pharmacology, 2019
Currently, the involvement of the endocannabinoid system in cancer development and possible options for a cancer-regressive effect of cannabinoids are controversially discussed.
Robert Ramer   +2 more
doaj   +1 more source

Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation

open access: yesMediators of Inflammation, 2016
Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
Kathleen L. McCoy
doaj   +1 more source

Gene expression of the endocannabinoid system in endometrium through menstrual cycle

open access: yesScientific Reports, 2022
Endocannabinoids mediate cellular functions and their activity is controlled by a complex system of enzymes, membrane receptors and transport molecules.
Keisuke Tanaka   +8 more
doaj   +1 more source

The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction

open access: yesPharmaceuticals, 2011
The endocannabinoid system (ECS) has been implicated in many physiological functions, including the regulation of appetite, food intake and energy balance, a crucial involvement in brain reward systems and a role in psychophysiological homeostasis ...
Francisco-Javier Bermúdez-Silva   +3 more
doaj   +1 more source

Peripheral endocannabinoids regulate skeletal muscle development and maintenance

open access: yesEuropean Journal of Translational Myology, 2010
As a principal tissue responsible for insulin-mediated glucose uptake, skeletal muscle is important for whole-body health. The role of peripheral endocannabinoids as regulators of skeletal muscle metabolism has recently gained a lot of interest, as ...
Dongjiao Zhao   +6 more
doaj   +1 more source

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