The endocannabinoid system (ECS) has been implicated in many physiological functions, including the regulation of appetite, food intake and energy balance, a crucial involvement in brain reward systems and a role in psychophysiological homeostasis ...
Francisco-Javier Bermúdez-Silva +3 more
doaj +1 more source
Peripheral endocannabinoids regulate skeletal muscle development and maintenance
As a principal tissue responsible for insulin-mediated glucose uptake, skeletal muscle is important for whole-body health. The role of peripheral endocannabinoids as regulators of skeletal muscle metabolism has recently gained a lot of interest, as ...
Dongjiao Zhao +6 more
doaj +1 more source
Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding [PDF]
Peer reviewedPublisher ...
Barabas, Klaudia +9 more
core +1 more source
The role of the endocannabinoid system in stress-related psychiatric symptoms has been investigated in many animal and human studies. Although most of these studies consistently report long-lasting effects of prolonged stress and trauma on the ...
Anahita Bassir Nia +2 more
doaj +1 more source
Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation [PDF]
The herb Cannabis sativa (C. sativa) has been used in China and on the Indian subcontinent for thousands of years as a medicine. However, since it was brought to the UK and then the rest of the western world in the late 19th century, its use has been a ...
Adams +215 more
core +3 more sources
Plasma anandamide and other N-acylethanolamines are correlated with their corresponding free fatty acid levels under both fasting and non-fasting conditions in women [PDF]
N-acylethanolamines (NAEs), such as anandamide (AEA), are a group of endogenous lipids derived from a fatty acid linked to ethanolamine and have a wide range of biological activities, including regulation of metabolism and food intake.
Balvers, M.G.J. +4 more
core +2 more sources
Growing evidence on the involvement of cannabinoids in the rewarding effects of various kinds of drugs of abuse has suggested that not only the classical dopaminergic and opioidergic, but also the most recently established endocannabinoid system is ...
Tsuneyuki Yamamoto +2 more
doaj +1 more source
2-arachidonoylglycerol metabolism is differently modulated by oligomeric and fibrillar conformations of amyloid beta in synaptic terminals [PDF]
Alzheimer´s disease (AD) is the most prevalent disorder of senile dementia mainly characterized by amyloid-beta peptide (Aβ) deposits in the brain. Cannabinoids are relevant to AD as they exert several beneficial effects in many models of this disease ...
Gaveglio, Virginia Lucía +3 more
core +1 more source
Role of Cannabinoids in the Regulation of Bone Remodelling
The endocannabinoid system plays a key role in regulating a variety of physiological processes such as appetite control and energy balance, pain perception, and immune responses. Recent studies have implicated the endocannabinoid system in the regulation
Aymen I Idris, Stuart H Ralston
doaj +1 more source
The endocannabinoid/cannabinoid receptor 2 system protects against cisplatin-induced hearing loss [PDF]
Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells ...
Asmita Dhukhwa +8 more
core +4 more sources

