Results 31 to 40 of about 46,188 (225)

The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction

open access: yesPharmaceuticals, 2011
The endocannabinoid system (ECS) has been implicated in many physiological functions, including the regulation of appetite, food intake and energy balance, a crucial involvement in brain reward systems and a role in psychophysiological homeostasis ...
Francisco-Javier Bermúdez-Silva   +3 more
doaj   +1 more source

Peripheral endocannabinoids regulate skeletal muscle development and maintenance

open access: yesEuropean Journal of Translational Myology, 2010
As a principal tissue responsible for insulin-mediated glucose uptake, skeletal muscle is important for whole-body health. The role of peripheral endocannabinoids as regulators of skeletal muscle metabolism has recently gained a lot of interest, as ...
Dongjiao Zhao   +6 more
doaj   +1 more source

Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding [PDF]

open access: yes, 2010
Peer reviewedPublisher ...
Barabas, Klaudia   +9 more
core   +1 more source

Endocannabinoid System Alterations in Posttraumatic Stress Disorder: A Review of Developmental and Accumulative Effects of Trauma

open access: yesChronic Stress, 2019
The role of the endocannabinoid system in stress-related psychiatric symptoms has been investigated in many animal and human studies. Although most of these studies consistently report long-lasting effects of prolonged stress and trauma on the ...
Anahita Bassir Nia   +2 more
doaj   +1 more source

Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation [PDF]

open access: yes, 2011
The herb Cannabis sativa (C. sativa) has been used in China and on the Indian subcontinent for thousands of years as a medicine. However, since it was brought to the UK and then the rest of the western world in the late 19th century, its use has been a ...
Adams   +215 more
core   +3 more sources

Plasma anandamide and other N-acylethanolamines are correlated with their corresponding free fatty acid levels under both fasting and non-fasting conditions in women [PDF]

open access: yes, 2010
N-acylethanolamines (NAEs), such as anandamide (AEA), are a group of endogenous lipids derived from a fatty acid linked to ethanolamine and have a wide range of biological activities, including regulation of metabolism and food intake.
Balvers, M.G.J.   +4 more
core   +2 more sources

New Perspectives in the Studies on Endocannabinoid and Cannabis: A Role for the Endocannabinoid-Arachidonic Acid Pathway in Drug Reward and Long-Lasting Relapse to Drug Taking

open access: yesJournal of Pharmacological Sciences, 2004
Growing evidence on the involvement of cannabinoids in the rewarding effects of various kinds of drugs of abuse has suggested that not only the classical dopaminergic and opioidergic, but also the most recently established endocannabinoid system is ...
Tsuneyuki Yamamoto   +2 more
doaj   +1 more source

2-arachidonoylglycerol metabolism is differently modulated by oligomeric and fibrillar conformations of amyloid beta in synaptic terminals [PDF]

open access: yes, 2017
Alzheimer´s disease (AD) is the most prevalent disorder of senile dementia mainly characterized by amyloid-beta peptide (Aβ) deposits in the brain. Cannabinoids are relevant to AD as they exert several beneficial effects in many models of this disease ...
Gaveglio, Virginia Lucía   +3 more
core   +1 more source

Role of Cannabinoids in the Regulation of Bone Remodelling

open access: yesFrontiers in Endocrinology, 2012
The endocannabinoid system plays a key role in regulating a variety of physiological processes such as appetite control and energy balance, pain perception, and immune responses. Recent studies have implicated the endocannabinoid system in the regulation
Aymen I Idris, Stuart H Ralston
doaj   +1 more source

The endocannabinoid/cannabinoid receptor 2 system protects against cisplatin-induced hearing loss [PDF]

open access: yes, 2018
Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells ...
Asmita Dhukhwa   +8 more
core   +4 more sources

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