Results 21 to 30 of about 20,782 (239)

Changes in plasma endocannabinoids concentrations correlate with 18F-FDG PET/MR uptake in brown adipocytes in humans

Frontiers in Molecular Biosciences, 2023
Introduction: Recent data suggest a possible role of endocannabinoids in the regulation of brown adipose tissue (BAT) activity. Those findings indicate potential treatment options for obesity.
Katarzyna Maliszewska, Katarzyna Miniewska, Adrian Godlewski, Wioleta Gosk, Malgorzata Mojsak, Adam Kretowski, Michal Ciborowski   +6 more
doaj   +1 more source

Activity-Dependent Modulation of Tonic GABA Currents by Endocannabinoids in Hirudo verbana

Frontiers in Synaptic Neuroscience, 2022
Endocannabinoids are lipid neuromodulators that are synthesized on demand and primarily signal in a retrograde manner to elicit depression of excitatory and inhibitory synapses.
Riley T. Paulsen, Brian D. Burrell
doaj   +1 more source

Endocannabinoids and exercise [PDF]

British Journal of Sports Medicine, 2004
Exercise induces changes in mental status, particularly analgesia, sedation, anxiolysis, and a sense of wellbeing. The mechanisms underlying these changes remain unknown. Recent findings show that exercise increases serum concentrations of endocannabinoids, suggesting a possible explanation for a number of these changes.
A, Dietrich, W F, McDaniel
openaire   +2 more sources

Endocannabinoids enhance hKV7.1/KCNE1 channel function and shorten the cardiac action potential and QT intervalResearch in context

EBioMedicine, 2023
Summary: Background: Genotype-positive patients who suffer from the cardiac channelopathy Long QT Syndrome (LQTS) may display a spectrum of clinical phenotypes, with often unknown causes.
Irene Hiniesto-Iñigo, Laura M. Castro-Gonzalez, Valentina Corradi, Mark A. Skarsfeldt, Samira Yazdi, Siri Lundholm, Johan Nikesjö, Sergei Yu Noskov, Bo Hjorth Bentzen, D. Peter Tieleman, Sara I. Liin   +10 more
doaj   +1 more source

Beyond the Activity-Based Anorexia Model: Reinforcing Values of Exercise and Feeding Examined in Stressed Adolescent Male and Female Mice

Frontiers in Pharmacology, 2019
Anorexia nervosa (AN), mostly observed in female adolescents, is the most fatal mental illness. Its core is a motivational imbalance between exercise and feeding in favor of the former.
Imane Hurel, Imane Hurel, Bastien Redon, Bastien Redon, Amandine Scocard, Amandine Scocard, Meryl Malezieux, Meryl Malezieux, Giovanni Marsicano, Giovanni Marsicano, Francis Chaouloff, Francis Chaouloff   +11 more
doaj   +1 more source

Endocannabinoid Turnover [PDF]

, 2017
In this review, we consider the biosynthetic, hydrolytic, and oxidative metabolism of the endocannabinoids anandamide and 2-arachidonoylglycerol. We describe the enzymes associated with these events and their characterization. We identify the inhibitor profile for these enzymes and the status of therapeutic exploitation, which to date has been limited ...
Fowler, Christopher J., Doherty, Patrick, Alexander, Stephen P.H.   +2 more
openaire   +4 more sources

An Operant Conditioning Task to Assess the Choice between Wheel Running and Palatable Food in Mice

Bio-Protocol, 2019
Wheel running, especially in the homecage, has been widely used to study the neurobiology of exercise because animal tends to use it voluntarily.
Bastien Redon, Imane Hurel, Giovanni Marsicano, Francis Chaouloff   +3 more
doaj   +1 more source

The Epigenetics of the Endocannabinoid System [PDF]

International Journal of Molecular Sciences, 2020
The endocannabinoid system (ES) is a cell-signalling system widely distributed in biological tissues that includes endogenous ligands, receptors, and biosynthetic and hydrolysing machineries. The impairment of the ES has been associated to several pathological conditions like behavioural, neurological, or metabolic disorders and infertility, suggesting
Meccariello Rosaria, Santoro Antonietta, DʹAngelo Stefania, Morrone Rossella, Fasano Silvia, Viggiano Andrea, Pierantoni Riccardo   +6 more
openaire   +2 more sources

Plasma concentrations of endocannabinoids and related primary Fatty Acid amides in patients with post-traumatic stress disorder. [PDF]

, 2013
Endocannabinoids (ECs) and related N-acyl-ethanolamides (NAEs) play important roles in stress response regulation, anxiety and traumatic memories. In view of the evidence that circulating EC levels are elevated under acute mild stressful conditions in ...
Kolassa, Iris-Tatjana, Schelling, G., Roozendaal, B., Campolongo, P., Gola, Hannah, Benno Roozendaal, Morath, Julia, Julia Morath, Vogeser, M., Alexander Karabatsiakis, Iris-Tatjana Kolassa, Atsak, Piray, Gustav Adolf Schelling, Patrizia Campolongo, Michael Vogeser, Piray Atsak, Campolongo, Patrizia, Roozendaal, Benno, Karabatsiakis, A., Gola, H., Schelling, Gustav, Vogeser, Michael, Iris Tatjana Kolassa, Atsak, P., Kolassa, I.T., Gilava Hamuni, Hannah Gola, Gustav Schelling, Daniela Hauer, Hamuni, G., Morath, J., Hauer, D., Karabatsiakis, Alexander, Hauer, Daniela, Hamuni, Gilava   +34 more
core   +2 more sources

Emerging mechanisms by which endocannabinoids and their derivatives modulate bacterial populations within the gut microbiome

Advances in Drug and Alcohol Research, 2023
Bioactive lipids such as endocannabinoids serve as important modulators of host health and disease through their effects on various host functions including central metabolism, gut physiology, and immunity.
Melissa Ellermann
doaj   +1 more source