Results 31 to 40 of about 19,236 (236)
Endocannabinoids in neuroendopsychology: multiphasic control of mitochondrial function [PDF]
, 2012 The endocannabinoid system (ECS) is a construct based on the discovery of receptors that are modulated by the plant compound tetrahydrocannabinol and the subsequent identification of a family of nascent ligands, the 'endocannabinoids'.
Guy, G.W. +8 more
core +1 more source
Stress, 2011 Endogenous cannabinoids play an important role in the physiology and behavioral expression of stress responses. Activation of the hypothalamic-pituitary-adrenal (HPA) axis, including the release of glucocorticoids, is the fundamental hormonal response to stress. Endocannabinoid (eCB) signaling serves to maintain HPA-axis homeostasis, by buffering basal
Riebe, C., Wotjak, C.
openaire +3 more sources
Journal of Lipid Research, 2017 Endocannabinoids, a class of lipid messengers, have emerged as crucial regulators of synaptic communication in the CNS. Dysregulation of these compounds has been implicated in many brain disorders.
Vasudev Kantae +10 more
doaj +1 more source
Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression [PDF]
, 2012 Background: Endocannabinoids (ECs) are rapidly acting immune-modulatory lipid-signaling molecules that are important for adaptation to stressful and aversive situations. They are known to interact with glucocorticoids and other stress-responsive systems.
Andres Beiras Fernandez +18 more
core +1 more source
Active endocannabinoids are secreted on extracellular membrane vesicles [PDF]
, 2015 Endocannabinoids primarily influence neuronal synaptic communication within the nervous system. To exert their function, endocannabinoids need to travel across the intercellular space.
Matteoli M +8 more
core +2 more sources
Scientific Reports, 2017 The endocannabinoid system is thought to modulate nociceptive signaling making it a potential therapeutic target for treating pain. However, there is evidence that endocannabinoids have both pro- and anti-nociceptive effects.
Torrie Summers +3 more
doaj +1 more source
Nutrition Journal, 2017 Background Besides the effects of dietary long chain PUFA on circulating endocannabinoids concentrations, the impact of other nutrients on these system is not known and, whether changes in plasma endocannabinoids levels correlated with changes in body ...
Fatemeh Haidari +3 more
doaj +1 more source
The association of dietary patterns with endocannabinoids levels in overweight and obese women
Lipids in Health and Disease, 2020 Background Higher levels of anandamide (AEA) and 2-arachidonoylglycerol (2-AG), the main arachidonic acid-derived endocannabinoids, are frequently reported in overweight and obese individuals. Recently, endocannabinoids have become a research interest in
Neda Lotfi Yagin +4 more
doaj +1 more source
Endocannabinoid Overload [PDF]
Molecular Pharmacology, 2010 The signaling capacity of endogenous cannabinoids ("endocannabinoids") is tightly regulated by degradative enzymes. This Perspective highlights a research article in this issue (p. 996) in which the authors show that genetic disruption of monoacylglycerol lipase (MAGL), the principal degradative enzyme for the endocannabinoid 2-arachidonoylglycerol (2 ...
Aron H, Lichtman +2 more
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Metabolism of endocannabinoids
Postępy Higieny i Medycyny Doświadczalnej, 2016 Endocannabinoids belong to a group of ester, ether and amide derivatives of fatty acids, which are endogenous ligands of receptors CB1, CB2, TRPV1 and GPR55 that are included in the endocannabinoid system of the animal organism. The best known endocannabinoids are: N-arachidonylethanolamide called anandamide (AEA) and 2-arachidonoylglycerol (2-AG ...
Michał, Biernacki +1 more
openaire +2 more sources