Results 51 to 60 of about 19,236 (236)
PLoS ONE, 2014 BackgroundEndocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females.
Fernando Fernández-Aranda +19 more
doaj +1 more source
Cannabinoid-dopamine interactions: Modulation of midbrain DA neurons by endocannabinoids
, 2015 A key feature of human and animal behavior is to learn from environmental stimuli to adapt efficiently. Under physiological conditions, dopaminergic (DA) neurons are used to evaluate and learn new sensory information and adjust behavior to maximize ...
François Georges +3 more
core +1 more source
Endocannabinoids and the Heart [PDF]
Journal of Cardiovascular Pharmacology, 2009 Endocannabinoids, such as anandamide and 2-arachidonoylglycerol, are synthesized from membrane phospholipids in the heart and other cardiovascular tissues. They activate cannabinoid CB1 and CB2 receptors, transient receptor potential V1 (TRPV1), peroxisome proliferator-activated receptors, and perhaps a novel vascular G-protein-coupled receptor ...
openaire +2 more sources
The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers
International Journal of Endocrinology, 2013 The “endocannabinoid system (ECS)” comprises the endocannabinoids, the enzymes that regulate their synthesis and degradation, the prototypical cannabinoid receptors (CB1 and CB2), some noncannabinoid receptors, and an, as yet, uncharacterised transport ...
Thangesweran Ayakannu +4 more
doaj +1 more source
New Insights Into Peptide Cannabinoids: Structure, Biosynthesis and Signaling
Frontiers in Pharmacology, 2020 Classically, the endocannabinoid system (ECS) consists of endogenous lipids, of which the best known are anandamide (AEA) and 2 arachidonoylglycerol (2-AG), their enzyme machinery for synthesis and degradation and their specific receptors, cannabinoid ...
Agustín Riquelme-Sandoval +7 more
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Journal of Cannabis Research, 2022 Endometriosis patients experience debilitating chronic pain, and the first-line treatment is ineffective at managing symptoms. Although surgical removal of the lesions provides temporary relief, more than 50% of the patients experience disease recurrence.
Harshavardhan Lingegowda +6 more
doaj +1 more source
mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling
Advanced Science, EarlyView.Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim +4 more
wiley +1 more source
Molecules, 2019 The hippocampus is thought to encode information by altering synaptic strength via synaptic plasticity. Some forms of synaptic plasticity are induced by lipid-based endocannabinoid signaling molecules that act on cannabinoid receptors (CB1 ...
Lindsey N. Friend +8 more
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Cannabinoids, Endocannabinoids and Sleep
Frontiers in Molecular Neuroscience, 2020 Sleep is a vital function of the nervous system that contributes to brain and bodily homeostasis, energy levels, cognitive ability, and other key functions of a variety of organisms. Dysfunctional sleep induces neural problems and is a key part of almost
Andrew J. Kesner +2 more
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2021 Objective: To investigate the antinociceptive effect of tingenone on inflammatory pain, as well as and the involvement of the cannabinoid receptors type 2 (CB2) and spinal microglia in this process.
Clarice C.V. Moura +3 more
doaj +1 more source