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Endocannabinoids and Schizophrenia
The endocannabinoids anandamide and 2-arachydonoylglycerol (2-AG) are lipids naturally derived from membrane precursors which bind cannabinoid receptors (CB1, CB2). This endocannabinoid system is disturbed in schizophrenia.
Stéphane Potvin +3 more
doaj +1 more source
The endocannabinoid/cannabinoid receptor 2 system protects against cisplatin-induced hearing loss [PDF]
Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells ...
Asmita Dhukhwa +8 more
core +4 more sources
Cannabinoids in the treatment of epilepsy: current status and future prospects [PDF]
Cannabidiol (CBD) is one of the prominent phytocannabinoids found in Cannabis sativa, differentiating from Δ9-tetrahydrocannabinol (THC) for its non-intoxicating profile and its antianxiety/antipsychotic effects.
Albini M. +6 more
core +1 more source
Genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP) and its association with Physiological mechanisms controlling Body Mass Index (BMI) [PDF]
Taste sensitivity to the bitter compound 6-n-propylthiouracil (PROP) is considered a marker for individual differences in taste perception that may influence food preferences and eating behavior, and thereby energy metabolism.
Banni S +4 more
core +1 more source
BackgroundEndocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females.
Fernando Fernández-Aranda +19 more
doaj +1 more source
Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio +5 more
core +2 more sources
The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers
The “endocannabinoid system (ECS)” comprises the endocannabinoids, the enzymes that regulate their synthesis and degradation, the prototypical cannabinoid receptors (CB1 and CB2), some noncannabinoid receptors, and an, as yet, uncharacterised transport ...
Thangesweran Ayakannu +4 more
doaj +1 more source
The hippocampus is thought to encode information by altering synaptic strength via synaptic plasticity. Some forms of synaptic plasticity are induced by lipid-based endocannabinoid signaling molecules that act on cannabinoid receptors (CB1 ...
Lindsey N. Friend +8 more
doaj +1 more source
Cannabinoids, Endocannabinoids and Sleep
Sleep is a vital function of the nervous system that contributes to brain and bodily homeostasis, energy levels, cognitive ability, and other key functions of a variety of organisms. Dysfunctional sleep induces neural problems and is a key part of almost
Andrew J. Kesner +2 more
doaj +1 more source
Endocannabinoids, particularly anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are instrumental in regulating energy homeostasis and stress response.
Isabel van Ackern +4 more
doaj +1 more source

