Results 171 to 180 of about 36,224 (218)

Enhanced bone regeneration via endochondral ossification using Exendin-4-modified mesenchymal stem cells. [PDF]

Bioact Mater
He Z, Li H, Zhang Y, Gao S, Liang K, Su Y, Du Y, Wang D, Xing D, Yang Z, Lin J.   +10 more
europepmc   +1 more source

Brd4 is required for chondrocyte differentiation and endochondral ossification

Bone, 2022
Differentiation of multi-potent mesenchymal stromal cells (MSCs) is directed by the activities of lineage-specific transcription factors and co-factors. A subset of these proteins controls the accessibility of chromatin by recruiting histone acetyl transferases or deacetylases that regulate acetylation of the N-termini of H3 and H4 histone proteins ...
Paradise, Christopher R., Galvan, M. Lizeth, Pichurin, Oksana, Jerez, Sofia, Kubrova, Eva, Dehghani, S. Sharare, Carrasco, Margarita E., Thaler, Roman, Larson, A. Noelle, van Wijnen, Andre J., Dudakovic, Amel   +10 more
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THE FATE OF CHONDROCYTES IN ENDOCHONDRAL OSSIFICATION IN THE RABBIT

The Journal of Bone and Joint Surgery. British volume, 1970
1. The epiphyses of the metatarsal heads of 250-gramme rabbits were separated at the zone of cell columns, stripped of perichondrium, labelled with tritiated thymidine and transplanted into the back muscles of the same animals. 2. Endochondral ossification started in the grafts at four days, was well established by seven days and progressed until ...
G, Bentley, R B, Greer
openaire   +3 more sources

Does static precede dynamic osteogenesis in endochondral ossification as occurs in intramembranous ossification?

The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology, 2006
Endochondral ossification takes place with calcified cartilage cores providing a rigid scaffold for new bone formation. Intramembranous ossification begins in connective tissue and new bone formed by a process of static ossification (SO) followed by ...
Laura Bertoni, Francesco Cavani, Marzia Ferretti   +2 more
exaly   +2 more sources

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The role of morphogens in endochondral ossification

Calcified Tissue International, 1992
The formation of bone occurs normally by one of two developmental processes: intramembranous or endochondral ossification. Endochondral ossification occurs in the morphogenesis of the limb buds and growth plates, and in the regeneration of bone following injury (fracture callus).
J T, Campbell, F S, Kaplan
openaire   +2 more sources

Endostatin inhibits endochondral ossification

The Journal of Gene Medicine, 2007
AbstractBackgroundAngiogenesis is essential for the replacement of cartilage by bone during skeletal growth and regeneration. Vascular endothelial growth factor‐A (VEGF‐A) is a key regulator of angiogenesis whereas endostatin, a potent inhibitor of endothelial cell proliferation and migration, is a natural antagonist of VEGF‐A.
A, Sipola, J, Ilvesaro, E, Birr, P, Jalovaara, R F, Pettersson, F, Stenbäck, S, Ylä-Herttuala, T, Hautala, J, Tuukkanen   +8 more
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Endochondral Ossification in Achondroplastic Dwarfism

New England Journal of Medicine, 1970
Abstract The literature concerning endochondral histopathology in the chondrodystrophies is misleading because the true heterogeneity of this group of disorders was not recognized until relatively ...
D L, Rimoin, G N, Hughes, R L, Kaufman, R E, Rosenthal, W H, McAlister, R, Silberberg   +5 more
openaire   +2 more sources

Mechanical stresses and endochondral ossification in the chondroepiphysis

Journal of Orthopaedic Research, 1988
AbstractIn 1911, Gebhardt used a photoelastic model to relate mechanical stresses to the ossification pattern of the chondroepiphysis. Pauwels later conducted a photoelastic study using the same model geometry to develop a theory that the secondary ossific nucleus originates at a position of high‐magnitude hydrostatic pressure where the shear stresses ...
D R, Carter, M, Wong
openaire   +2 more sources

Matrix Vesicles as a Marker of Endochondral Ossification

Connective Tissue Research, 1990
Endochondral ossification in bone development and repair, and in induced bone formation in mesenchymal tissues, involves recruitment of mesenchymal cells, their differentiation into chondrocytes, and calcification of the cartilagenous matrix. Stimulation of proteoglycan synthesis is used as a biochemical marker of chondrogenesis, however it does not ...
B D, Boyan, Z, Schwartz, L D, Swain
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Aspects of the glycome of endochondral ossification

2022
ABSTRACT Comparatively little is known about the glycome (the set of glycans and glycoconjugates made by the cell, tissue or organism) of bone and cartilage. The glycome has a high-density coding capacity and is important in post-translational modification.
Sheena F McClure, John McClure
openaire   +1 more source