Results 191 to 200 of about 18,079 (225)
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Matrix Vesicles as a Marker of Endochondral Ossification
Connective Tissue Research, 1990Endochondral ossification in bone development and repair, and in induced bone formation in mesenchymal tissues, involves recruitment of mesenchymal cells, their differentiation into chondrocytes, and calcification of the cartilagenous matrix. Stimulation of proteoglycan synthesis is used as a biochemical marker of chondrogenesis, however it does not ...
B D, Boyan, Z, Schwartz, L D, Swain
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Aspects of the glycome of endochondral ossification
2022ABSTRACT Comparatively little is known about the glycome (the set of glycans and glycoconjugates made by the cell, tissue or organism) of bone and cartilage. The glycome has a high-density coding capacity and is important in post-translational modification.
Sheena F McClure, John McClure
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Effect of therapeutic ultrasound on endochondral ossification
Ultrasound in Medicine & Biology, 1995The effect of therapeutic doses of ultrasound was tested on endochondral ossification of in vitro developing metatarsal long bone rudiments of 16- and 17-day-old fetal mice. Bone growth, calcification and resorption following exposure to several doses of pulse-wave (PW) or continuous-wave (CW) ultrasound were examined.
Wiltink, A. +4 more
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Endochondral ossification and the evolution of limb proportions
WIREs Developmental Biology, 2020AbstractMammals have remarkably diverse limb proportions hypothesized to have evolved adaptively in the context of locomotion and other behaviors. Mechanistically, evolutionary diversity in limb proportions is the result of differential limb bone growth.
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Defective endochondral ossification in brachymorphic mice
Journal of Comparative Pathology, 1977Abstract In mice of a brachymorphic strain, endochondral ossification was characterized by the absence of hypertrophy and by disorientation of the cartilage closest to the metaphysis. The change is considered to be qualitative, and the abnormality in these mice should thus not be classified as achondroplasia.
R, Silberberg, P, Lesker
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Process Heterochronies in Endochondral Ossification
Journal of Theoretical Biology, 2000Heterochrony, evolutionary changes in developmental rates and timing, is a key concept in the construction of a synthesis of development and evolution. Heterochronic changes in vertebrate evolution have traditionally been identified through plesiomorphic-apomorphic comparisons of bone growth.
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The emergence of mechanoregulated endochondral ossification in evolution
Journal of Biomechanics, 2013The differentiation of skeletal tissue phenotypes is partly regulated by mechanical forces. This mechanoregulatory aspect of tissue differentiation has been the subject of many experimental and computational investigations. However, little is known about what factors promoted the emergence of mechanoregulated tissue differentiation in evolution, even ...
Hanifeh, Khayyeri +1 more
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Origin and development of septoclasts in endochondral ossification of mice
Histochemistry and Cell Biology, 2018Septoclasts are mononuclear spindle-shaped phagocytes with their long processes in uncalcified cartilage matrices and locate adjacent to the capillary endothelium at the chondro-osseous junction of the growth plate. We have previously revealed a selective expression of epidermal-type fatty acid-binding protein (E-FABP/FABP5) in septoclasts.
Yasuhiko, Bando +7 more
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Inhibitory effect of bFGF on endochondral heterotopic ossification
Biochemical and Biophysical Research Communications, 2002Basic fibroblast growth factor (bFGF) is reported to stimulate repair of fracture and bony defects in in vivo animal studies. However, most studies performed in vitro demonstrate inhibitory effect of bFGF on cartilage and bone differentiation. To understand the discrepancy observed in in vivo and in vitro studies, we evaluated the effect of bFGF on ...
Shinji, Sakano +7 more
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A biochemical strategy for simulation of endochondral and intramembranous ossification
Computer Methods in Biomechanics and Biomedical Engineering, 2013Following the assumption that parathyroid hormone related protein and Indian hedgehog form a biochemical regulatory loop for the endochondral process and bone morphogenetic protein 2 and Noggin in the intramembranous process, this paper implements these regulatory mechanisms.
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