Results 11 to 20 of about 45,559 (245)

GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells

open access: yesCell Reports, 2021
SUMMARY In addition to driving specific gene expression profiles, transcriptional regulators are becoming increasingly recognized for their capacity to modulate chromatin structure.
James A. Heslop   +3 more
semanticscholar   +1 more source

A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture. [PDF]

open access: yesPLoS ONE, 2012
Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation.
Svetlana Vassilieva   +6 more
doaj   +1 more source

Complete Dorsal Pancreatic Agenesis and Unilateral Renal Agenesis: First Case Report and Review of Literature [PDF]

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2016
Dorsal pancreatic agenesis is very rare congenital anomaly of pancreas. Patients with this anomaly are usually asymptomatic or may present with abdominal pain or acute or chronic pancreatitis.
Manjit Motilal Bagul, Purva Traipathi
doaj   +1 more source

Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids

open access: yesbioRxiv, 2020
Shaping the animal body plan is a complex process that involves the spatial organization and patterning of different layers of cells. Recent advances in live imaging have started to unravel the cellular choreography underlying this process in mammals ...
Ali Hashmi   +4 more
semanticscholar   +1 more source

In Vivo Regulation of the Zebrafish Endoderm Progenitor Niche by T-Box Transcription Factors

open access: yesCell Reports, 2017
T-box transcription factors T/Brachyury homolog A (Ta) and Tbx16 are essential for correct mesoderm development in zebrafish. The downstream transcriptional networks guiding their functional activities are poorly understood.
Andrew C. Nelson   +5 more
doaj   +1 more source

A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

open access: yeseLife, 2020
Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown ...
Bjoern Gaertner   +10 more
doaj   +1 more source

Corn root morphoanatomy at different development stages and yield under water stress [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2016
: The objective of this work was to characterize the morphoanatomy of roots and the yield traits of two corn hybrids contrasting for drought tolerance (DKB 390, tolerant; and BRS 1030, sensitive), at different stages of development.
Thiago Corrêa de Souza   +4 more
doaj   +1 more source

In vitro generation of human pluripotent stem cell derived lung organoids

open access: yeseLife, 2015
Recent breakthroughs in 3-dimensional (3D) organoid cultures for many organ systems have led to new physiologically complex in vitro models to study human development and disease.
Briana R Dye   +12 more
doaj   +1 more source

Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes

open access: yeseLife, 2017
The evolutionary origins of the hypoxia-sensitive cells that trigger amniote respiratory reflexes – carotid body glomus cells, and ‘pulmonary neuroendocrine cells’ (PNECs) - are obscure.
Dorit Hockman   +16 more
doaj   +1 more source

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