Results 21 to 30 of about 45,559 (245)
T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation
eLife, 2023 Long non-coding RNAs (lncRNAs) have emerged as fundamental regulators in various biological processes, including embryonic development and cellular differentiation. Despite much progress over the past decade, the genome-wide annotation of lncRNAs remains
Alexandro Landshammer +19 more
doaj +1 more source
Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells
Nature Communications, 2014 Florence Wianny +2 more
exaly +2 more sources
Frontiers in Medicine, 2019 In recent years, advances in human pluripotent stem cell (hPSC) biology have enabled the generation of gastrointestinal (GI) organoids which recapitulate aspects of normal organ development.
Abdelkader Daoud, Jorge O. Múnera
doaj +1 more source
GATA6-AS1 Regulates GATA6 Expression to Modulate Human Endoderm Differentiation
Stem Cell Reports, 2020 Summary Transcriptome analysis has uncovered a series of long noncoding RNAs (lncRNAs) transcribed during cell differentiation, but how lncRNA is integrated with known transcriptional regulatory network is poorly understood.
Jie Yang +5 more
semanticscholar +1 more source
Stem Cell Research, 2018 Liver organogenesis requires complex cell-cell interactions between hepatic endoderm cells and adjacent cell niches. Endothelial cells are key players for endoderm hepatic fate decision. We previously demonstrated that the endothelial cell niche promotes
Songyan Han +5 more
doaj +1 more source
Mature Mediastinal Teratoma [PDF]
Journal of Clinical and Diagnostic Research, 2015 A teratoma is a tumour with tissue or organ components resembling normal derivatives of more than one germ layer. We present a case of mediastinal mature teratoma as they have a low incidence rate.
Chikka Narasimhaiah Anushree +1 more
doaj +1 more source
Development, 2019 Embryonic stem cells (ESCs) exist in at least two states that transcriptionally resemble different stages of embryonic development. Naïve ESCs resemble peri-implantation stages and primed ESCs the pre-gastrulation epiblast.
Madeleine Linneberg-Agerholm +5 more
semanticscholar +1 more source
Endoderm and heart development [PDF]
Developmental Dynamics, 2000 Since the first half of the 20th century, experimental embryologists have noted a relationship between endoderm cells and the development of cardiac tissue from mesoderm. During the past decade, the accumulation of evidence for an obligatory interaction between endoderm and mesoderm during the specification and terminal differentiation of myocardial ...
J, Lough, Y, Sugi
openaire +2 more sources
Stem/progenitor cells in the developing human lung
Journal of Pediatric and Neonatal Individualized Medicine, 2016 Human lungs are composed of more than 40 cell types. The lung is classified as a “conditionally renewing” tissue and is able of a quick response to cellular damage thanks to the presence of multiple stem/progenitor cells.
Daniela Fanni +6 more
doaj +1 more source
lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation
bioRxiv, 2019 Cooperation between DNA, RNA and protein regulates gene expression and controls differentiation through interactions that connect regions of nucleic acids and protein domains and through the assembly of biomolecular condensates.
Kaveh Daneshvar +16 more
semanticscholar +1 more source