Results 41 to 50 of about 45,559 (245)
Dynamics of Drosophila endoderm specification
Proceedings of the National Academy of Sciences, 2022 Significance To understand developmental patterning of an organism, it is necessary to accurately measure how the state of a gene regulatory network is changing over time. One way of extracting dynamics of a network involves simultaneously imaging several reporters within fixed tissue.
Shannon E. Keenan +5 more
openaire +2 more sources
Ingression-type cell migration drives vegetal endoderm internalisation in the Xenopus gastrula
eLife, 2017 During amphibian gastrulation, presumptive endoderm is internalised as part of vegetal rotation, a large-scale movement that encompasses the whole vegetal half of the embryo. It has been considered a gastrulation process unique to amphibians, but we show
Jason W H Wen, R. Winklbauer
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
In vitro Symbiosis of Reef-Building Coral Cells With Photosynthetic Dinoflagellates
Frontiers in Marine Science, 2021 Coral reefs are the biodiversity hot spots of the oceans, but they have suffered from increasing environmental stresses caused principally by anthropogenic global warming.
Kaz Kawamura +6 more
doaj +1 more source
Cell Reports, 2016 Organogenesis of the trachea and lungs requires a complex series of mesoderm-endoderm interactions mediated by WNT, BMP, retinoic acid (RA), and hedgehog (Hh), but how these pathways interact in a gene regulatory network is less clear.
S. Rankin +9 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier +7 more
wiley +1 more source
A case report of craniovertebral junction intradural extramedullary neurenteric cyst
Medical Journal of Dr. D.Y. Patil University, 2014 A neurenteric cyst of the craniocervical (CV) junction, as a cause of bulbomedullary compression, is very rare. An abnormal communication between the endoderm and neuroectoderm during the third week of embryogenesis may be responsible for its formation ...
Rajeshwari S Vhora +3 more
doaj +1 more source
Building like a Coral—Parallelized, Multiscale Biofabrication
Advanced Materials, EarlyView.Corals build stiff, strong, and inherently circular skeletal materials under resource‐ and energy‐limited conditions—offering blueprints for transformative materials. We synthesize the current understanding of coral biomineralization and reframe coral growth as a multiscale, parallelized biofabrication process.
Asma Rehman +5 more
wiley +1 more source
FEBS Open Bio, 2021 Thyroid dysgenesis (TD) is a major cause of primary congenital hypothyroidism; however, the molecular mechanism underlying this process is unclear.
Rui‐jia Zhang +6 more
doaj +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source