Results 11 to 20 of about 32,233 (214)

Matrix metalloproteinases: A double edge sword

open access: yesDentistry and Medical Research, 2016
Dental caries is a dynamic process which results in demineralization of inorganic constituents and destruction of organic structure of the tooth. The basic mechanism of inorganic demineralization has been studied and documented well enough.
Praveen Kumar Bali   +3 more
doaj   +1 more source

PBP4 Is Likely Involved in Cell Division of the Longitudinally Dividing Bacterium Candidatus Thiosymbion Oneisti

open access: yesAntibiotics, 2021
Peptidoglycan (PG) is essential for bacterial survival and maintaining cell shape. The rod-shaped model bacterium Escherichia coli has a set of seven endopeptidases that remodel the PG during cell growth.
Jinglan Wang   +4 more
doaj   +1 more source

Presence and expression of hydrogenase specific C-terminal endopeptidases in cyanobacteria

open access: yesBMC Microbiology, 2003
Background Hydrogenases catalyze the simplest of all chemical reactions: the reduction of protons to molecular hydrogen or vice versa. Cyanobacteria can express an uptake, a bidirectional or both NiFe-hydrogenases.
Lindblad Peter   +2 more
doaj   +1 more source

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

open access: yesNature Communications, 2020
Asparaginyl endopeptidases (AEPs) catalyze the cyclization step during the biosynthesis of cyclic peptides in plants. Here, the authors report a recombinantly produced AEP that catalyzes the backbone cyclization of a linear cyclotide precursor and an ...
Junqiao Du   +9 more
doaj   +1 more source

Downregulation of MMP-2 and MMP-9 genes in obesity patients and their relation with obesity-related phenotypes

open access: yesTürk Biyokimya Dergisi, 2022
Adipose tissue mediates various bioactive molecules and cytokine discharge. The anti-inflammatory cytokine, interleukin-10 (IL-10), has roles in systemic inflammation.
Aksoyer Sezgin Saadet Busra   +6 more
doaj   +1 more source

Characterisation of a putative M23-domain containing protein in Mycobacterium tuberculosis.

open access: yesPLoS ONE, 2021
Mycobacterium tuberculosis, the causative agent of tuberculosis remains a global health concern, further compounded by the high rates of HIV-TB co-infection and emergence of multi- and extensive drug resistant TB, all of which have hampered efforts to ...
Andrea Olga Papadopoulos   +4 more
doaj   +2 more sources

Activity Gel Analysis of Endopeptidases in Rose Petals

open access: yesHorticultural Plant Journal, 2016
Poor resolution for the identification of endopeptidase (EP) activity in activity gel assays is a critical issue in the analysis of the postharvest physiology of rose petals. In this paper, major factors influencing EP activity gel assays were evaluated.
Xiting Zhao   +4 more
doaj   +1 more source

Plant Viral Proteases: Beyond the Role of Peptide Cutters

open access: yesFrontiers in Plant Science, 2018
Almost half of known plant viral species rely on proteolytic cleavages as key co- and post-translational modifications throughout their infection cycle. Most of these viruses encode their own endopeptidases, proteases with high substrate specificity that
Bernardo Rodamilans   +3 more
doaj   +1 more source

Frozen fresh blood plasma preserves the functionality of native human α2-macroglobulin

open access: yesScientific Reports, 2023
Human α2-macroglobulin (hα2M) is a large homotetrameric protein involved in the broad inhibition of endopeptidases. Following cleavage within a bait region, hα2M undergoes stepwise transitions from its native, expanded, highly flexible, active ...
Soraia R. Mendes   +2 more
doaj   +1 more source

Streptococcus endopeptidases promote HPV infection in vitro

open access: yesMicrobiologyOpen, 2019
Both cervical and throat cancers are associated with human papillomavirus (HPV). HPV infection requires cleavage of the minor capsid protein L2 by furin.
Sylvia I. Pavlova   +5 more
doaj   +1 more source

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