Results 21 to 30 of about 35,058 (249)

Downregulation of MMP-2 and MMP-9 genes in obesity patients and their relation with obesity-related phenotypes

open access: yesTürk Biyokimya Dergisi, 2022
Adipose tissue mediates various bioactive molecules and cytokine discharge. The anti-inflammatory cytokine, interleukin-10 (IL-10), has roles in systemic inflammation.
Aksoyer Sezgin Saadet Busra   +6 more
doaj   +1 more source

Two new cysteine endopeptidases obtained from the latex of Araujia hortorum fruits [PDF]

open access: yes, 2022
Two new endopeptidases were purified to homogeneity from the latex of Araujia hortorum fruits by a simple purification procedure involving ultracentrifugation and ion exchange chromatography.
Obregón, Walter David   +5 more
core  

Characterisation of a putative M23-domain containing protein in Mycobacterium tuberculosis.

open access: yesPLoS ONE, 2021
Mycobacterium tuberculosis, the causative agent of tuberculosis remains a global health concern, further compounded by the high rates of HIV-TB co-infection and emergence of multi- and extensive drug resistant TB, all of which have hampered efforts to ...
Andrea Olga Papadopoulos   +4 more
doaj   +2 more sources

Activity Gel Analysis of Endopeptidases in Rose Petals

open access: yesHorticultural Plant Journal, 2016
Poor resolution for the identification of endopeptidase (EP) activity in activity gel assays is a critical issue in the analysis of the postharvest physiology of rose petals. In this paper, major factors influencing EP activity gel assays were evaluated.
Xiting Zhao   +4 more
doaj   +1 more source

Plant Viral Proteases: Beyond the Role of Peptide Cutters

open access: yesFrontiers in Plant Science, 2018
Almost half of known plant viral species rely on proteolytic cleavages as key co- and post-translational modifications throughout their infection cycle. Most of these viruses encode their own endopeptidases, proteases with high substrate specificity that
Bernardo Rodamilans   +3 more
doaj   +1 more source

Frozen fresh blood plasma preserves the functionality of native human α2-macroglobulin

open access: yesScientific Reports, 2023
Human α2-macroglobulin (hα2M) is a large homotetrameric protein involved in the broad inhibition of endopeptidases. Following cleavage within a bait region, hα2M undergoes stepwise transitions from its native, expanded, highly flexible, active ...
Soraia R. Mendes   +2 more
doaj   +1 more source

Streptococcus endopeptidases promote HPV infection in vitro

open access: yesMicrobiologyOpen, 2019
Both cervical and throat cancers are associated with human papillomavirus (HPV). HPV infection requires cleavage of the minor capsid protein L2 by furin.
Sylvia I. Pavlova   +5 more
doaj   +1 more source

Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases.

open access: yesPLoS ONE, 2017
Allosteric targeting is progressively gaining ground as a strategy in drug design. Its success, however, depends on our knowledge of the investigated system.
Marko Novinec
doaj   +1 more source

Insights into the mechanism of cyanobacteria removal by the algicidal fungi Bjerkandera adusta and Trametes versicolor

open access: yesMicrobiologyOpen, 2020
Fungal mycelia can eliminate almost all cocultured cyanobacterial cells within a short time. However, molecular mechanisms of algicidal fungi are poorly understood.
Guomin Han   +7 more
doaj   +1 more source

Endopeptidases da Canavalia ensiformis : um estudo da germinação e estágios iniciais da plântula [PDF]

open access: yes, 2007
Endopeptidases de diversas classes da semente quiescente e plântulas de Canavalia ensiformis foram investigadas neste trabalho. Aplicando técnicas de purificação e caracterização de proteínas identificamos e isolamos endopeptidases representantes de ...
Demartini, Diogo Ribeiro   +1 more
core   +1 more source

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