Results 21 to 30 of about 34,911 (258)
Hypothalamic CREB Regulates the Expression of Pomc-Processing Enzyme Pcsk2
Cells, 2022 Background: The hypothalamic proopiomelanocortin (Pomc) neurons act as first-order sensors of systemic energy stores, providing signals that regulate caloric intake and energy expenditure.
Ariane Maria Zanesco +6 more
doaj +1 more source
Asparaginyl endopeptidases: enzymology, applications and limitations [PDF]
, 2021 Asparaginyl endopeptidases (AEP) are cysteine proteases found in mammalian and plant cells. Several AEP isoforms from plant species were found to exhibit transpeptidase activity which is integral for the key head-to-tail cyclisation reaction during the ...
Tang, Tsz Man Simon Louis +1 more
core +1 more source
Macrocyclization by asparaginyl endopeptidases [PDF]
New Phytologist, 2017 Contents Summary 923 I. Introduction 923 II. Plant AEPs with macrocyclizing ability 924 III. Mechanism of macrocyclization by AEPs 925 IV. Conclusions 927 Acknowledgements 927 References 927 SummaryPlant asparaginyl endopeptidases (AEPs) are important for the post‐translational processing of seed storage proteins via ...
Amy M, James +2 more
openaire +2 more sources
Ruminal Proteolysis in Forages with Distinct Endopeptidases Activities [PDF]
, 2023 Improving livestock efficiency in utilisation of nitrogen resources continues to be a major environmental and economic objective. Zhu et al. (1999) have shown that plant endopeptidases are activated as a response to cutting stress.
Tapia, C., Pichard, G., Larrain, R.
core +3 more sources
Frontiers in Microbiology, 2021 Peptidoglycan (PG) hydrolases play important roles in various aspects of bacterial physiology, including cytokinesis, PG synthesis, quality control of PG, PG recycling, and antibiotic resistance. However, the regulatory mechanisms of their expression are
Yung Jae Kim +7 more
doaj +1 more source
Two novel IgG endopeptidases of Streptococcus equi
, 2009 Streptococcus equi ssp. equi causes strangles, a highly contagious and serious disease in the upper respiratory tract of horses. Streptococcus equi ssp. zooepidemicus, another subspecies of this genus, is regarded as an opportunistic commensal in horses.
Hulting, Greta, +3 more
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Differential expression of mRNAs for endopeptidases in phenotypically modulated (`dedifferentiated') human articular chondrocytes [PDF]
, 1997 Human articular chondrocytes modulated away from their original phenotype by serial subcultures in monolayer differentially express mRNAs for endopeptidases.
Georgios Kostoulas +7 more
core +1 more source
PLoS ONE, 2017 Allosteric targeting is progressively gaining ground as a strategy in drug design. Its success, however, depends on our knowledge of the investigated system.
Marko Novinec
doaj +1 more source
MicrobiologyOpen, 2020 Fungal mycelia can eliminate almost all cocultured cyanobacterial cells within a short time. However, molecular mechanisms of algicidal fungi are poorly understood.
Guomin Han +7 more
doaj +1 more source
Amyloid beta and Alzheimer’s Disease: The role of neprilysin-2 in amyloid-beta clearance
Frontiers in Aging Neuroscience, 2014 Accumulation of the amyloid-beta (Ab) peptide is a central factor in Alzheimer’s disease (AD) pathogenesis as supported by continuing evidence. This review concisely summarizes this evidence supporting a critical role for Ab in AD before discussing the ...
Robert eMarr, Daniel eHafez
doaj +1 more source