Results 111 to 120 of about 16,681 (209)

Sex differences in stress-modulated cocaine vulnerability: female rodents are more sensitive to the effects of stress exposure at different developmental stages

Frontiers in Behavioral Neuroscience
IntroductionStressful life events can trigger the initiation of cocaine use, facilitate the transition to a cocaine-use disorder (CUD), and precipitate relapse. Evidence suggests that women progress more rapidly to a CUD than men.
María Ángeles Martínez-Caballero, Claudia Calpe-López, Maria Pilar García-Pardo, M. Carmen Arenas, Carmen Manzanedo, María A. Aguilar   +5 more
doaj   +1 more source

Endophenotype 2.0: updated definitions and criteria for endophenotypes of psychiatric disorders, incorporating new technologies and findings

Translational Psychiatry
Recent genetic studies have linked numerous loci to psychiatric disorders. However, the biological pathways that connect these genetic associations to psychiatric disorders’ specific pathophysiological processes are largely unclear. Endophenotypes, first
Chunyu Liu, Elliot S. Gershon
doaj   +1 more source

Editorial: Is autism a biological entity?

Frontiers in Psychiatry, 2023
Lynn Waterhouse, Laurent Mottron
doaj   +1 more source

Endophenotypes: multiplicity of variants and possible interpretations

Современная зарубежная психология, 2012
The concept of endophenotype comprises hereditary characteristics of human body and psyche, correlating with behavioral (psychological) displays of normal functioning and mental disorders.
Maryutina T.M.
doaj  

Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: a potential databank from China

, 2010
Endophenotypic research can be considered to be one of the most promising strategies to bridge the gap between genomic complexity and the phenotypic heterogeneity observed in neuropsychiatric disorders.
Chan, Raymond C. K., Gottesman, Irving I., Sham, Pak C., Ge, Xiaojia   +3 more
core  

Syntactic Networks as an Endophenotype of Developmental Language Disorders: An Evo-Devo Approach to Clinical Linguistics

Biolinguistics, 2015
Lluís Barceló-Coblijn, Antonio Benítez-Burraco, Aritz Irurtzun   +2 more
doaj   +1 more source

Brain multiomic profiling identifies tau-related transcriptomic dysregulation in Alzheimer's disease. [PDF]

Brain Commun
Oatman SR, Quicksall ZS, Wang X, Bergman J, Reddy JS, Vanelderen F, Nguyen T, Malphrus K, Lincoln SJ, Martens YA, Zhao N, Yamazaki Y, DeTure M, Murray ME, Liu CC, Bu G, Kanekiyo T, Dickson DW, Allen M, Ertekin-Taner N.   +19 more
europepmc   +1 more source

Identification of clinical-biological endophenotypes in patients with eosinophilic granulomatosis with polyangiitis using unsupervised machine learning: a real-world study. [PDF]

Respir Res
Sun B, Wang Z, Li Y, Zhao R, Shen K, Lian H, Liu Y, Lin J, Ni X.   +8 more
europepmc   +1 more source

Associations of dementia polyexposure scores to Alzheimer's disease endophenotypes in a diverse population. [PDF]

Alzheimers Dement
Okorie M, Jiang X, Yaffe K, Yokoyama JS, Andrews SJ, Health and Aging Brain Study–Health Disparities.   +5 more
europepmc   +1 more source

Genetic Insights Into Protective Effects of GLP-1 Receptor Agonists on Stroke and Alzheimer Disease Across Ancestries. [PDF]

Neurol Genet
Caro-Châtelier I, Sargurupremraj M, Yang C, Akinleye C, Trégouët DA, Akinyemi RO, Shigemizu D, Coker M, Akinyemi JO, Tiwari HK, Chasman DI, Ovbiagele B, Chabriat H, Mooser V, Couffinhal T, Mishra A, Cruchaga C, Reitz C, Kunkle B, Kamatani Y, Owolabi MO, Mohammedi K, Debette S.   +22 more
europepmc   +1 more source