Results 101 to 110 of about 16,681 (209)

Overcoming treatment-resistant depression with machine-learning based tools: a study protocol combining EEG and clinical data to personalize glutamatergic and brain stimulation interventions (SelecTool Project)

Frontiers in Psychiatry
Treatment-Resistant Depression (TRD) poses a substantial health and economic challenge, persisting as a major concern despite decades of extensive research into novel treatment modalities.
Mauro Pettorruso, Mauro Pettorruso, Mauro Pettorruso, Giorgio Di Lorenzo, Giorgio Di Lorenzo, Beatrice Benatti, Giacomo d’Andrea, Giacomo d’Andrea, Clara Cavallotto, Rosalba Carullo, Gianluca Mancusi, Ornella Di Marco, Giovanna Mammarella, Antonio D’Attilio, Elisabetta Barlocci, Ilenia Rosa, Alessio Cocco, Lorenzo Pio Padula, Giovanna Bubbico, Mauro Gianni Perrucci, Mauro Gianni Perrucci, Roberto Guidotti, Roberto Guidotti, Roberto Guidotti, Antea D’Andrea, Laura Marzetti, Laura Marzetti, Francesca Zoratto, Bernardo Maria Dell’Osso, Giovanni Martinotti, Giovanni Martinotti, Giovanni Martinotti, Giovanni Martinotti   +32 more
doaj   +1 more source

Integrated Biomarker–Volumetric Profiling Defines Neurodegenerative Subtypes and Predicts Neuroaxonal Injury in Multiple Sclerosis Based on Bayesian and Machine Learning Analyses

Biomedicines
Background: The clinical–radiological paradox in multiple sclerosis (MS) underscores the need for biomarkers that better reflect neurodegenerative pathology.
Alin Ciubotaru, Roxana Covali, Cristina Grosu, Daniel Alexa, Laura Riscanu, Bîlcu Robert-Valentin, Radu Popa, Gabriela Dumachita Sargu, Cristina Popa, Cristiana Filip, Laura-Elena Cucu, Albert Vamanu, Victor Constantinescu, Emilian Bogdan Ignat   +13 more
doaj   +1 more source

Endophenotypes in psychiatric disease: prospects and challenges

, 2018
Editorial summary Endophenotypes, quantitative neurobehavioral traits that index genetic susceptibility for a psychiatric disorder, have been examined in thousands of studies.
William G. Iacono
core   +1 more source

Modern Perspectives on the Mechanisms and Non-Genetic Factors in Ménière’s Disease—A Narrative Review

Biomedicines
Ménière’s disease is a complex disorder of the inner ear, characterized by recurrent episodes of vertigo, progressive hearing loss, tinnitus, and aural fullness.
Iustin Mihai Iațentiuc, Otilia Elena Frăsinariu, Andreea Iațentiuc, Lucia Corina Dima-Cozma, Raluca Olariu, Elena Tătăranu, Alexandru Florescu, Andreea Moaleș, Andrei Osman, Mihaela Durnea, Ionuț Daniel Iancu, Sebastian Romică Cozma, Oana Roxana Bitere-Popa   +12 more
doaj   +1 more source

Biomarkers for mood disorders: A scoping review of research from India

Indian Journal of Psychiatry
Background: Mood disorders pose significant diagnostic and therapeutic challenges. While biomarkers can improve diagnostic accuracy and personalize treatment, their geographic validation remains limited.
Varshitha Tholasappa, Varna P. Baidebettu, Hariprasad G. Vijaykumar, Preethi V. Reddy, Rashmi Arasappa, Muralidharan Kesavan   +5 more
doaj   +1 more source

Qualifying brain functional MRI parameters as endophenotypes in schizophrenia

, 2010
Although the genetic contribution to schizophrenia pathogenesis has been well established, with an approximate heritability of 81%, the endeavor to elucidate the complex genetic architecture of schizophrenia has met limited success.
WatersMetenier, SL, Toulopoulou, T, Timothea Toulopoulou, Sheena Lindsey Waters-Metenier   +3 more
core   +1 more source

Fear-themed digital media exposure and sleep regulatory sensitivity in school-aged children: preliminary observations toward a developmental PhenoSleep construct

Frontiers in Neurology
IntroductionFear-themed digital media exposure is increasingly common in school-aged children, yet its developmental implications remain insufficiently understood.
Martina Gnazzo, Martina Gnazzo, Martina Gnazzo, Giuditta Bargiacchi, Giuditta Bargiacchi, Eva Germanò, Eva Germanò, Agata Maltese, Agata Maltese, Lucia Parisi, Lucia Parisi, Laura Firrigno, Michele Roccella, Michele Roccella, Giulia Spoto, Gabriella Di Rosa, Gabriella Di Rosa, Lidia Scifo, Beatrice Gallai, Beatrice Gallai, Davide Testa, Annamaria Maddalena Terracciano, Marco Carotenuto, Marco Carotenuto   +23 more
doaj   +1 more source

Endophenotypes in psychiatric genetics [PDF]

Molecular Psychiatry, 2007
J T R, Walters, M J, Owen
openaire   +2 more sources

Validating endophenotypes for schizophrenia using statistical modeling of twin data

, 2008
The use of endophenotypes (intermediate quantitative traits) is one strategy that may provide valuable information about the neural mechanisms underlying disease etiology and facilitate discovery of susceptibility genes.
Hall, M H, Rijsdijk, F
core   +3 more sources

Endophenotyping Schizophrenia [PDF]

American Journal of Psychiatry, 2007
David Braff, Nicholas J. Schork, Irving I. Gottesman   +2 more
openaire   +2 more sources