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Endoplasmic reticulum stress in lung cancer [PDF]

open access: yesFrontiers in Oncology
Endoplasmic reticulum is the primary site of eukaryotic cells involved in biosynthesis, lipid metabolism, glucose metabolism, protein folding and secretion.
Donghuan Zhang   +6 more
doaj   +2 more sources

Location matters: the endoplasmic reticulum and protein trafficking in dendrites

open access: yesBiological Research, 2011
Neurons are highly polarized, but the trafficking mechanisms that operate in these cells and the topological organization of their secretory organelles are still poorly understood.
Omar A Ramírez   +2 more
doaj  

Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells

open access: yesEndocrine Regulations, 2019
Objective. The aim of the present study was to examine the effect of glucose deprivation on the expression of genes encoded glucocorticoid receptor (NR3C1) and some related proteins (NR3C2, AHR, NRIP1, NNT, ARHGAP35, SGK1, and SGK3) in U87 glioma cells ...
Riabovol Olena O.   +6 more
doaj   +1 more source

Melatonin Induces Anti-Inflammatory Effects to Play a Protective Role via Endoplasmic Reticulum Stress in Acute Pancreatitis

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: Melatonin, which is mainly secreted by the pineal gland and released into blood, has anti-inflammatory properties in acute pancreatitis. Many studies show that melatonin can relieve inflammation in taurocholate-induced acute pancreatitis.
Yina Chen   +6 more
doaj   +1 more source

Endoplasmic reticulum phosphate transport

open access: yesKidney International, 1996
The major role of the liver endoplasmic reticulum phosphate/pyrophosphate transport proteins is the regulation of blood glucose levels. The glucose-6-phosphatase enzyme is an endoplasmic reticulum enzyme system which hydrolyzes glucose-6-phosphate to glucose and phosphate.
openaire   +2 more sources

Exosomes derived from microglia overexpressing miR-124-3p alleviate neuronal endoplasmic reticulum stress damage after repetitive mild traumatic brain injury

open access: yesNeural Regeneration Research
[INLINE:1] We previously reported that miR-124-3p is markedly upregulated in microglia-derived exosomes following repetitive mild traumatic brain injury.
Yan Wang   +14 more
doaj   +1 more source

Endoplasmic Reticulum

open access: yes
Citation: 'endoplasmic reticulum' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15662 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Penfluridol induces endoplasmic reticulum stress leading to autophagy in pancreatic cancer

open access: yesTumor Biology, 2017
Pancreatic cancer is one of the most aggressive and difficult to treat cancers. Experimental and clinical evidence suggests that high basal state autophagy in pancreatic tumors could induce resistance to chemotherapy.
Alok Ranjan   +4 more
doaj   +1 more source

MAM-mediated mitophagy and endoplasmic reticulum stress: the hidden regulators of ischemic stroke

open access: yesFrontiers in Cellular Neuroscience
Ischemic stroke (IS) is the predominant subtype of stroke and a leading contributor to global mortality. The mitochondrial-associated endoplasmic reticulum membrane (MAM) is a specialized region that facilitates communication between the endoplasmic ...
Ziyi Jia   +8 more
doaj   +1 more source

TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells

open access: yesCell Death Discovery
The release of Ca2+ ions from endoplasmic reticulum calcium stores is a key event in a variety of cellular processes, including gene transcription, migration and proliferation.
Alice H. L. Bong   +7 more
doaj   +1 more source

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