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Research Progress on Endoplasmic Reticulum Stress-Mediated Apoptosis and Its Regulatory Mechanism on Muscle Tenderization [PDF]

open access: yesShipin Kexue
The endoplasmic reticulum is a key site for calcium storage, lipid synthesis, protein synthesis, transport and folding, and it performs several critical biological functions.
LI Chenlong, LUO Yulong, DONG Yushan, DU Xuerong, YAO Lili, HOU Yanru, WANG Jiayu, XU Shengyun
doaj   +1 more source

Epithelial-mesenchymal transition induces endoplasmic-reticulum-stress response in human colorectal tumor cells. [PDF]

open access: yesPLoS ONE, 2014
Tumor cells are stressed by unfavorable environmental conditions like hypoxia or starvation. Driven by the resulting cellular stress tumor cells undergo epithelial-mesenchymal transition.
Evelyn Zeindl-Eberhart   +7 more
doaj   +1 more source

THE ENDOPLASMIC RETICULUM [PDF]

open access: yesThe Journal of Cell Biology, 1956
and (b) the vesicular character of its component elements, were already clearly noted in its first description. In subsequent papers, Porter and his collaborators described the preferential concentration of the vesicular elements of the reticulum in the endoplasm, and their scarcity or absence in the supposedly exoplasmic periphery of the cytoplasm (2,
openaire   +2 more sources

STING an Endoplasmic Reticulum Adaptor that Facilitates Innate Immune Signaling

open access: yesNature, 2008
The cellular innate immune system is essential for recognizing pathogen infection and for establishing effective host defence. But critical molecular determinants responsible for facilitating an appropriate immune response—following infection with DNA ...
Hiroki Ishikawa, G. Barber
semanticscholar   +1 more source

Membrane contact sites - an interesting species, an interesting mix [PDF]

open access: yes, 2013
In this issue of EMBO reports, Loewen and colleagues reveal a role for plasma membrane–endoplasmic reticulum contact sites in regulating phosphatidylcholine synthesis in budding ...
Miller, Vicky J, Stephens, David J
core   +2 more sources

Inhibition of endoplasmic reticulum stress alleviates secondary injury after traumatic brain injury

open access: yesNeural Regeneration Research, 2018
Apoptosis after traumatic brain injury has been shown to be a major factor influencing prognosis and outcome. Endoplasmic reticulum stress may be involved in mitochondrial mediated neuronal apoptosis. Therefore, endoplasmic reticulum stress has become an
Hong-Ping Tan   +4 more
doaj   +1 more source

Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids and its modification by Stearoyl-CoA desaturases and cyclic AMP [PDF]

open access: yes, 2011
Podocyte apoptosis is a hallmark in the development and progression of diabetic nephropathy (DN). Several factors of the diabetic milieu are known to induce podocyte apoptosis. Currently, the role of free fatty acids (FFAs) for podocytopathy and podocyte
Sieber, Jonas
core   +1 more source

Endoplasmic reticulum as a target in cardiovascular diseases: Is there a role for flavonoids?

open access: yesFrontiers in Pharmacology, 2023
Flavonoids are found in natural health products and plant-based foods. The flavonoid molecules contain a 15-carbon skeleton with the particular structural construction of subclasses.
Kimia Keylani   +18 more
doaj   +1 more source

Coming together to define membrane contact sites. [PDF]

open access: yes, 2019
Close proximities between organelles have been described for decades. However, only recently a specific field dealing with organelle communication at membrane contact sites has gained wide acceptance, attracting scientists from multiple areas of cell ...
De Matteis, Maria Antonietta   +14 more
core   +7 more sources

KRE5 Suppression Induces Cell Wall Stress and Alternative ER Stress Response Required for Maintaining Cell Wall Integrity in Candida glabrata. [PDF]

open access: yesPLoS ONE, 2016
The maintenance of cell wall integrity in fungi is required for normal cell growth, division, hyphae formation, and antifungal tolerance. We observed that endoplasmic reticulum stress regulated cell wall integrity in Candida glabrata, which possesses ...
Yutaka Tanaka   +7 more
doaj   +1 more source

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