Inhibition of endoplasmic reticulum stress alleviates secondary injury after traumatic brain injury
Neural Regeneration Research, 2018 Apoptosis after traumatic brain injury has been shown to be a major factor influencing prognosis and outcome. Endoplasmic reticulum stress may be involved in mitochondrial mediated neuronal apoptosis. Therefore, endoplasmic reticulum stress has become an
Hong-Ping Tan +4 more
doaj +1 more source
Oncology Report, 2021 External and internal stimuli are often involved in the pathogenesis of tumors, and the deterioration of endoplasmic reticulum (ER) function within cells is also an important etiological factor of tumorigenesis resulting in the impairment of the ...
Xiaojing Fu +6 more
semanticscholar +1 more source
Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise [PDF]
, 2013 Pathological endoplasmic reticulum (ER) stress is tightly linked to the accumulation of reactive oxidants, which can be both upstream and downstream of ER stress.
Julia Birk +11 more
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The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. [PDF]
, 2001 Cargo selection and export from the endoplasmic reticulum is mediated by the COPII coat machinery that includes the small GTPase Sar1 and the Sec23/24 and Sec13/31 complexes.
Bannykh, Sergei +20 more
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Endoplasmic reticulum as a target in cardiovascular diseases: Is there a role for flavonoids?
Frontiers in Pharmacology, 2023 Flavonoids are found in natural health products and plant-based foods. The flavonoid molecules contain a 15-carbon skeleton with the particular structural construction of subclasses.
Kimia Keylani +18 more
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Endoplasmic reticulum stress signals in the tumour and its microenvironment
Nature Reviews. Cancer, 2020 Protein handling, modification and folding in the endoplasmic reticulum (ER) are tightly regulated processes that determine cell function, fate and survival.
Xi Chen, J. Cubillos-Ruiz
semanticscholar +1 more source
The endoplasmic reticulum in plant immunity and cell death [PDF]
, 2012 The endoplasmic reticulum (ER) is a highly dynamic organelle in eukaryotic cells and a major production site of proteins destined for vacuoles, the plasma membrane, or apoplast in plants.
Ruth eEichmann +5 more
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KRE5 Suppression Induces Cell Wall Stress and Alternative ER Stress Response Required for Maintaining Cell Wall Integrity in Candida glabrata. [PDF]
PLoS ONE, 2016 The maintenance of cell wall integrity in fungi is required for normal cell growth, division, hyphae formation, and antifungal tolerance. We observed that endoplasmic reticulum stress regulated cell wall integrity in Candida glabrata, which possesses ...
Yutaka Tanaka +7 more
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The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles [PDF]
, 2000 Members of the yeast p24 family, including Emp24p and Erv25p, form a heteromeric complex required for the efficient transport of selected proteins from the endoplasmic reticulum (ER) to the Golgi apparatus.
Muñiz Guinea, Manuel +11 more
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Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling [PDF]
, 2012 Many cellular processes including apoptosis, autophagy, translation, energy metabolism, and inflammation are controlled by the mammalian target of rapamycin (mTOR) kinase and the endoplasmic reticulum (ER) stress pathway, also known as the unfolded ...
Appenzeller-Herzog, Christian +1 more
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