Altered Endoplasmic Reticulum Calcium Pump Expression during Breast Tumorigenesis
Breast Cancer: Basic and Clinical Research, 2011 Endoplasmic reticulum calcium homeostasis is involved in several essential cell functions including cell proliferation, protein synthesis, stress responses or secretion.
Béla Papp, Jean-Philippe Brouland
doaj +2 more sources
Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes : salicylate alleviates this stress [PDF]
, 2010 Recent findings indicate that endoplasmic reticulum (ER) stress is significantly increased in adipose tissue of obese human subjects and is critical to the initiation and integration of pathways of inflammation and insulin action.
Saif Alhusaini +18 more
core +1 more source
Endoplasmic reticulum : shape and function in stress translation [PDF]
, 2014 The endoplasmic reticulum (ER) is a very versatile organelle. Besides its major role as the gateway to the secretory pathway the ER is central to adaptation against abiotic and biotic stress.
Stephen H. Howell +12 more
core +1 more source
Uterine Endoplasmic Reticulum Stress and Its Unfolded Protein Response May Regulate Caspase 3 Activation in the Pregnant Mouse Uterus [PDF]
, 2013 We have previously proposed that uterine caspase-3 may modulate uterine contractility in a gestationally regulated fashion. The objective of this study was to determine the mechanism by which uterine caspase-3 is activated and consequently controlled in ...
Subedi, Kalpana +17 more
core +2 more sources
The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles [PDF]
, 2000 Members of the yeast p24 family, including Emp24p and Erv25p, form a heteromeric complex required for the efficient transport of selected proteins from the endoplasmic reticulum (ER) to the Golgi apparatus.
Muñiz Guinea, Manuel +15 more
core +1 more source
The endoplasmic reticulum in plant immunity and cell death [PDF]
, 2012 The endoplasmic reticulum (ER) is a highly dynamic organelle in eukaryotic cells and a major production site of proteins destined for vacuoles, the plasma membrane, or apoplast in plants.
Ruth eEichmann +5 more
core +1 more source
The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. [PDF]
, 2001 Cargo selection and export from the endoplasmic reticulum is mediated by the COPII coat machinery that includes the small GTPase Sar1 and the Sec23/24 and Sec13/31 complexes.
Bannykh, Sergei +20 more
core +1 more source
KRE5 Suppression Induces Cell Wall Stress and Alternative ER Stress Response Required for Maintaining Cell Wall Integrity in Candida glabrata. [PDF]
PLoS ONE, 2016 The maintenance of cell wall integrity in fungi is required for normal cell growth, division, hyphae formation, and antifungal tolerance. We observed that endoplasmic reticulum stress regulated cell wall integrity in Candida glabrata, which possesses ...
Yutaka Tanaka +7 more
doaj +1 more source
Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise [PDF]
, 2013 Pathological endoplasmic reticulum (ER) stress is tightly linked to the accumulation of reactive oxidants, which can be both upstream and downstream of ER stress.
Julia Birk +15 more
core +1 more source
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling [PDF]
, 2012 Many cellular processes including apoptosis, autophagy, translation, energy metabolism, and inflammation are controlled by the mammalian target of rapamycin (mTOR) kinase and the endoplasmic reticulum (ER) stress pathway, also known as the unfolded ...
Appenzeller-Herzog, Christian +3 more
core +1 more source