Results 11 to 20 of about 462,885 (376)
Endoplasmic reticulum stress in lung disease [PDF]
European Respiratory Review, 2017 Exposure to inhaled pollutants, including fine particulates and cigarette smoke is a major cause of lung disease in Europe. While it is established that inhaled pollutants have devastating effects on the genome, it is now recognised that additional ...
Stefan J. Marciniak
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Endoplasmic Reticulum Stress in Cancer [PDF]
MedCommPersistent and intense endoplasmic reticulum (ER) stress is widely acknowledged as a hallmark of tumorigenesis. To restore ER homeostasis, cells activate the unfolded protein response (UPR), which is aberrantly regulated in cancer cells.
Ruixin Zhou +5 more
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Ferroptosis and endoplasmic reticulum stress in ischemic stroke
Neural Regeneration Research, 2023 Ferroptosis is a form of non-apoptotic programmed cell death, and its mechanisms mainly involve the accumulation of lipid peroxides, imbalance in the amino acid antioxidant system, and disordered iron metabolism.
Yina Li +6 more
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Endoplasmic reticulum stress in lung cancer [PDF]
Frontiers in OncologyEndoplasmic reticulum is the primary site of eukaryotic cells involved in biosynthesis, lipid metabolism, glucose metabolism, protein folding and secretion.
Donghuan Zhang +6 more
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Endoplasmic reticulum stress and organoids [PDF]
Organoid, 2021 Organoids represent an advanced tool in cell biology and have redefined biomedical research. Organoids are ideal for studies of biological processes, pharmacological studies, and therapeutic research to imitate pathological processes and preserve genetic
Rashedul Alam +3 more
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Endoplasmic reticulum stress and pulmonary hypertension [PDF]
Pulmonary Circulation, 2020 Pulmonary hypertension is a fatal disease of which pulmonary vasculopathy is the main pathological feature resulting in the mean pulmonary arterial pressure higher than 25 mmHg.
Yanan Hu +5 more
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Endoplasmic reticulum stress in diseases
MedCommThe endoplasmic reticulum (ER) is a key organelle in eukaryotic cells, responsible for a wide range of vital functions, including the modification, folding, and trafficking of proteins, as well as the biosynthesis of lipids and the maintenance of ...
Yingying Liu +5 more
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Endoplasmic Reticulum Stress and Associated ROS [PDF]
International Journal of Molecular Sciences, 2016 The endoplasmic reticulum (ER) is a fascinating network of tubules through which secretory and transmembrane proteins enter unfolded and exit as either folded or misfolded proteins, after which they are directed either toward other organelles or to ...
H. M. A. Zeeshan +3 more
semanticscholar +4 more sources
Research progress on the role of endoplasmic reticulum stress in osteoarthritis [PDF]
Jichu yixue yu linchuang, 2023 Osteoarthritis is a common degenerative disease in which endoplasmic reticulum stress(ER stress) plays an important role in the pathogenesis of chondrocyte apoptosis.
JIN Tao, YANG Qingshan, WU Shujin, ZHU Xiaoyan, SHI Yucong, NIU Jianxiong, LIU Lin
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Uterine Endoplasmic Reticulum Stress and Its Unfolded Protein Response May Regulate Caspase 3 Activation in the Pregnant Mouse Uterus [PDF]
, 2013 We have previously proposed that uterine caspase-3 may modulate uterine contractility in a gestationally regulated fashion. The objective of this study was to determine the mechanism by which uterine caspase-3 is activated and consequently controlled in ...
Condon, Jennifer C. +5 more
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