Results 41 to 50 of about 462,885 (376)

RBM10 Regulates Embryonic Trophoblast Injury via Endoplasmic Reticulum Stress

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: Previous studies shown that RNA binding motif proteins (RBM) participate in regulating various physiological processes such as cell autophagy, proliferation, and apoptosis, and are abnormally highly expressed in placental trophoblast cells ...
Xiao Chen, Juan Du, Liyu Chen, Lanlan Wang, Gang Xin   +4 more
doaj   +1 more source

Research progress of endoplasmic reticulum stress of hypoxic pulmonary hypertension [PDF]

Jichu yixue yu linchuang, 2023
Hypoxic pulmonary hypertension (HPH) is a serious complication caused by long-term hypoxia,which is characterized by persistent vasoconstriction and irreversible vascular remodeling.
LIU Xingxing, WANG Weiwei, YUAN Haoxin
doaj   +1 more source

Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]

, 2014
BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P, Dries, DL, Felkin, LE, Lee, R, Rame, JE, Xu, B   +5 more
core   +1 more source

The aftermath of the interplay between the endoplasmic reticulum stress response and redox signaling

Experimental and Molecular Medicine, 2021
The endoplasmic reticulum (ER) is an essential organelle of eukaryotic cells. Its main functions include protein synthesis, proper protein folding, protein modification, and the transportation of synthesized proteins.
K. R. Bhattarai, Thoufiqul Alam Riaz, Hyung-Ryong Kim, H. Chae   +3 more
semanticscholar   +1 more source

KRE5 Suppression Induces Cell Wall Stress and Alternative ER Stress Response Required for Maintaining Cell Wall Integrity in Candida glabrata. [PDF]

PLoS ONE, 2016
The maintenance of cell wall integrity in fungi is required for normal cell growth, division, hyphae formation, and antifungal tolerance. We observed that endoplasmic reticulum stress regulated cell wall integrity in Candida glabrata, which possesses ...
Yutaka Tanaka, Masato Sasaki, Fumie Ito, Toshio Aoyama, Michiyo Sato-Okamoto, Azusa Takahashi-Nakaguchi, Hiroji Chibana, Nobuyuki Shibata   +7 more
doaj   +1 more source

Mechanism of Endoplasmic Reticulum Stress Pathway in the Osteogenic Phenotypic Transformation of Aortic Valve Interstitial Cells

Frontiers in Endocrinology, 2022
Background and PurposeCalcific Aortic Valve Disease (CAVD) is a crucial component of degenerative valvular disease in old age and with the increasing prevalence of the aging population.
Yiming Tao, Yiming Tao, Yimin Geng, Yimin Geng, Wenpei Dang, Wenpei Dang, Xinxin Xu, Xinxin Xu, Hui Zhao, Hui Zhao, Lijuan Zou, Lijuan Zou, Yongsheng Li, Yongsheng Li   +13 more
doaj   +1 more source

β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. [PDF]

, 2010
ObjectiveThe islet in type 2 diabetes is characterized by β-cell apoptosis, β-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP).
Butler, Alexandra E, Butler, Peter C, Costes, Safia, Daval, Marie, Gurlo, Tatyana, Huang, Chang-jiang, Matveyenko, Aleksey V, Rizza, Robert A   +7 more
core   +2 more sources

TorsinA participates in endoplasmic reticulum-associated degradation [PDF]

, 2013
TorsinA is an \(AAA^+\) ATPase located within the lumen of the endoplasmic reticulum and nuclear envelope, with a mutant form causing early onset torsion dystonia (DYT1).
Armata, Ioanna A., Breakefield, Xandra Owens, Caldwell, Guy A., Caldwell, Kim A., Chen, Pan, Cho, JinAh, da Hora, Cintia Carla, Farley, Jonathan E., Klein, Christine, Lencer, Wayne I., Nery, Flávia C., Tagaya, Mitsuo, Tannous, Bakhos A., Wang, Qiuyan, Yaqub, Uzma, Ye, Yihong   +15 more
core   +1 more source

Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons

Journal of experimental & clinical cancer research : CR, 2021
Solid tumors often grow in a micro-environment characterized by
M. Akman, D. Belisario, I. Salaroglio, J. Kopecka, Massimo Donadelli, E. De Smaele, C. Riganti   +6 more
semanticscholar   +1 more source

Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation. [PDF]

, 2017
Atherosclerosis impacts arteries where disturbed blood flow renders the endothelium susceptible to inflammation. Cytokine activation of endothelial cells (EC) upregulates VCAM-1 receptors that target monocyte recruitment to atherosusceptible regions ...
Bailey, Keith A, Haj, Fawaz G, Passerini, Anthony G, Simon, Scott I   +3 more
core   +1 more source