Results 241 to 250 of about 47,261 (313)
The integration of atomically precise gold nanoclusters with peptides or drugs represents a cutting‐edge class of nanomaterials in the biomedical field, owing to their unique physicochemical properties such as water solubility, excellent biocompatibility, low toxicity, and good renal clearance.
Rebeca Garcia Moura +2 more
wiley +1 more source
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella +10 more
wiley +1 more source
Intracellular delivery of nanomaterials: How to catch endosomal escape in the act
Thomas Martens +4 more
openalex +2 more sources
Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang +7 more
wiley +1 more source
Breaking in and busting out: cell-penetrating peptides and the endosomal escape problem
Julia C. LeCher +2 more
openalex +1 more source
Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles [PDF]
Laura I. Selby +3 more
openalex +1 more source
Transient Cyclic Structured Oligonucleotide Designs for Therapeutic Applications
Abstract Oligonucleotide‐based therapeutics are now widely used in clinical settings. From the late 1980s to the mid‐1990s, efforts to improve therapeutic efficacy focused on imparting drug‐like properties to oligonucleotides, emphasizing nuclease stability and target sequence affinity.
Sudhir Agrawal
wiley +1 more source
<i>In vivo</i> demonstration of enhanced mRNA delivery by cyclic disulfide-containing lipid nanoparticles for facilitating endosomal escape. [PDF]
Kimura S +9 more
europepmc +1 more source
A newly established 3D correlative cryogenic fluorescence microscopy, focused ion beam scanning electron microscopy, and soft x‐ray tomography workflow allowed for enough contrast and resolution to quantify the intracellular uptake of zirconyl‐containing inorganic–organic hybrid nanoparticles as a novel chemotherapeutic drug delivery system into ...
Pavitra Sokke Rudraiah +7 more
wiley +1 more source

