Results 241 to 250 of about 47,261 (313)

Peptide and Drug‐Protected Gold Nanoclusters as Promising Biomaterials: Synthesis, Properties, and Applications

open access: yesAggregate, Volume 7, Issue 2, February 2026.
The integration of atomically precise gold nanoclusters with peptides or drugs represents a cutting‐edge class of nanomaterials in the biomedical field, owing to their unique physicochemical properties such as water solubility, excellent biocompatibility, low toxicity, and good renal clearance.
Rebeca Garcia Moura   +2 more
wiley   +1 more source

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 2, Page 310-323, February 2026.
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella   +10 more
wiley   +1 more source

Intracellular delivery of nanomaterials: How to catch endosomal escape in the act

open access: bronze, 2014
Thomas Martens   +4 more
openalex   +2 more sources

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

open access: yesChemistryEurope, Volume 4, Issue 2, February 2026.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang   +7 more
wiley   +1 more source

Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles [PDF]

open access: bronze, 2017
Laura I. Selby   +3 more
openalex   +1 more source

Transient Cyclic Structured Oligonucleotide Designs for Therapeutic Applications

open access: yesCurrent Protocols, Volume 6, Issue 2, February 2026.
Abstract Oligonucleotide‐based therapeutics are now widely used in clinical settings. From the late 1980s to the mid‐1990s, efforts to improve therapeutic efficacy focused on imparting drug‐like properties to oligonucleotides, emphasizing nuclease stability and target sequence affinity.
Sudhir Agrawal
wiley   +1 more source

Combining Correlative Cryogenic Fluorescence and Electron Microscopy and Correlative Cryogenic Super‐Resolution Fluorescence and X‐Ray Tomography—Novel Complementary 3D Cryo‐Microscopy Across Scales to Reveal Nanoparticle Internalization Into Cancer Cells

open access: yesMicroscopy Research and Technique, Volume 89, Issue 2, Page 260-272, February 2026.
A newly established 3D correlative cryogenic fluorescence microscopy, focused ion beam scanning electron microscopy, and soft x‐ray tomography workflow allowed for enough contrast and resolution to quantify the intracellular uptake of zirconyl‐containing inorganic–organic hybrid nanoparticles as a novel chemotherapeutic drug delivery system into ...
Pavitra Sokke Rudraiah   +7 more
wiley   +1 more source

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