Results 101 to 110 of about 187,332 (400)

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

Inhibition of early EHDV2-Ibaraki infection steps in bovine cells by endosome alkalinization or ikarugamycin, but not by blockage of individual endocytic pathways

Frontiers in Cellular and Infection Microbiology
The Epizootic hemorrhagic disease virus (EHDV), an orbivirus, is the etiological factor of a fatal hemorrhagic disease of wild ruminants. A subset of EHDV serotypes, including the Ibaraki strain of EHDV2 (EHDV2-Ibaraki), infect and cause disease in ...
Maya Malka, Inbar Czaczkes, Shlomi Kashkash, Shirel Shachar, Eran Bacharach, Marcelo Ehrlich   +5 more
doaj   +1 more source

Vγ9Vδ2 T Cells Activation Through Phosphoantigens Can Be Impaired by a RHOB Rerouting in Lung Cancer

Frontiers in Immunology, 2020
Vγ9Vδ2 T cells are known to be efficient anti-tumor effectors activated through phosphoantigens (PAg) that are naturally expressed by tumor cells or induced by amino bisphosphonates treatment.
Chloé Laplagne, Chloé Laplagne, Chloé Laplagne, Sarah Meddour, Sarah Meddour, Sarah Meddour, Sarah Figarol, Sarah Figarol, Sarah Figarol, Marie Michelas, Marie Michelas, Marie Michelas, Olivier Calvayrac, Olivier Calvayrac, Olivier Calvayrac, Gilles Favre, Gilles Favre, Gilles Favre, Gilles Favre, Camille Laurent, Camille Laurent, Camille Laurent, Camille Laurent, Jean-Jacques Fournié, Jean-Jacques Fournié, Jean-Jacques Fournié, Stéphanie Cabantous, Stéphanie Cabantous, Stéphanie Cabantous, Mary Poupot, Mary Poupot, Mary Poupot   +31 more
doaj   +1 more source

CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING [PDF]

, 2017
Endocytosis is a process by which cells internalize membrane proteins to remove them from the plasma membrane, allowing cells to regulate the cell surface expression of transmembrane proteins.
Sirisaengtaksin, Natalie, Sirisaengtaksin, Natalie   +1 more
core   +1 more source

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska, A Pratelli, A Quan, Aleksandra Milewska, AM Zaki, Artur Szczepanski, B Hernaez, B Jancekova, BA Mainou, BJ Dille, C Burkard, C Kooi, C Liu, C Liu, D Dutta, DM Blau, E Dietzel, E Girard, E Hamme Van, EJ Bowman, F Samson, G Preta, GA Wudiri, GM Li, GR Ares, H Imhoff, H Lin, H Wang, IC Huang, IM Mackay, J Li, J Schindelin, J Somsel Rodman, JA Mitchell, JK Millet, JL Wang, JP Lim, JR Henley, Judy A. Mitchell, K Erles, K Erles, K Owczarek, K Shirato, K Shirato, Katarzyna Owczarek, Krzysztof Pyrc, KS Choi, L Kleist von, L Pelkmans, LH Wang, LJ Reed, M Marsh, MG Hemida, MJ Geisow, MJ Vincent, O Achour, O Heikkila, P Duckert, P Eifart, P Oh, Q Xu, R Nomura, S Bertram, S Bolte, S Gierer, S Matsuyama, SL Priestnall, TA Hill, VC Chu, X Ren, Y Inoue, Y Phonphok, Z Qian, Z Qinfen, Zbigniew Baster, Zenon Rajfur   +75 more
core   +8 more sources

Peroxisomes, lipid droplets, and endoplasmic reticulum “hitchhike” on motile early endosomes

Journal of Cell Biology, 2015
Microtubule-dependent long-range motility of early endosomes supports directed motility of peroxisomes, lipid droplets, and endoplasmic reticulum, and this process is mediated by transient interaction between all three organelles and the endosomes.
Sofia C. Guimarães, M. Schuster, E. Bielska, Gulay Dagdas, Sreedhar Kilaru, Ben R.A. Meadows, M. Schrader, G. Steinberg   +7 more
semanticscholar   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Mechanisms of Entry and Endosomal Pathway of African Swine Fever Virus

Vaccines, 2017
African Swine Fever Virus (ASFV) causes a serious swine disease that is endemic in Africa and Sardinia and presently spreading in Russia and neighboring countries, including Poland and recently, the Czech Republic.
Elena G. Sánchez, Daniel Pérez-Núñez, Yolanda Revilla   +2 more
doaj   +1 more source

Acid-Labile Traceless Click Linker for Protein Transduction [PDF]

, 2012
Intracellular delivery of active proteins presents an interesting approach in research and therapy. We created a protein transduction shuttle based on a new traceless click linker that combines the advantages of click reactions with implementation of ...
Bachelder E. M., Dohmen C., Engin K., Ernst Wagner, Frohlich T., Kevin Maier, Lee Y., Meyer M., Meyer M., Meyer M., Miyata K., Murphy R. F., Murthy N., Nieto M. A., Rozema D. B., Rozema D. B., Saxon E., Schaffert D., Vallee M. R., Wagner E., Wagner E., Yu H.   +21 more
core   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source