Results 11 to 20 of about 187,332 (400)
Loss of KEAP1 Causes an Accumulation of Nondegradative Organelles
Antioxidants, 2022 KEAP1 is a cytoplasmic protein that functions as an adaptor for the Cullin-3-based ubiquitin E3 ligase system, which regulates the degradation of many proteins, including NFE2L2/NRF2 and p62/SQSTM1.
Elisabet Uribe-Carretero +12 more
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Frontiers in Cell and Developmental Biology, 2021 Tight-junction (TJ) proteins are essential for establishing the barrier function between neighbor epithelial cells, but also for recognition of pathogens or cell migration.
Clara Maria Mateos-Quiros +8 more
doaj +1 more source
The EMBO Journal, 2011 Being deeply connected to signalling, cell dynamics, growth, regulation, and defence, endocytic processes are linked to almost all aspects of cell life and disease. In this review, we focus on endosomes in the classical endocytic pathway, and on the programme of changes that lead to the formation and maturation of late endosomes/multivesicular bodies ...
Huotari J, Helenius A.
openaire +2 more sources
Crinum latifolium extract inhibits lipopolysaccharide-induced inflammation in human macrophages
Romanian Journal of Laboratory Medicine, 2022 Introduction: Crinum latifolium is a natural plant showing the anti-inflammatory effects. We aimed to evaluate the effects of Crinum latifolium extract on proinflammatory cytokine production and maturation of early and late endosomes in the ...
Köktürk Sibel +2 more
doaj +1 more source
Proton-Activated Chloride Channel: Physiology and Disease
Frontiers in Bioscience-Landmark, 2023 The maintenance of intracellular and extracellular pH relies on multiple ion transporters/channels. Proton-activated chloride channel (PAC) precisely regulates extracellular and early/late endosomal pH by transporting chloride ion (Cl-) across membranes ...
Fanglin Peng +3 more
doaj +1 more source
The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7
Cell Reports, 2021 Summary: Endocytosis and endosome dynamics are controlled by proteins of the small GTPase Rab family. Besides possible recycling routes to the plasma membrane and various organelles, previously described endocytic pathways (e.g., clathrin-mediated ...
Evgeniya Trofimenko +3 more
doaj +1 more source
Frontiers in Microbiology, 2023 Aflatoxins, a family of fungal secondary metabolites, are toxic and carcinogenic compounds that pose an enormous threat to global food safety and agricultural sustainability.
Rubaiya Jesmin +10 more
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HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes
Cell, 2009 Gregory B Melikyan
exaly +2 more sources
A microscopy-based kinetic analysis of yeast vacuolar protein sorting
eLife, 2020 Saccharomyces cerevisiae is amenable to studying membrane traffic by live-cell fluorescence microscopy. We used this system to explore two aspects of cargo protein traffic through prevacuolar endosome (PVE) compartments to the vacuole.
Jason C Casler, Benjamin S Glick
doaj +1 more source
Real-time visualization of clustering and intracellular transport of gold nanoparticles by correlative imaging. [PDF]
, 2017 Mechanistic understanding of the endocytosis and intracellular trafficking of nanoparticles is essential for designing smart theranostic carriers. Physico-chemical properties, including size, clustering and surface chemistry of nanoparticles regulate ...
Chen, Nan +13 more
core +2 more sources