Results 21 to 30 of about 107,563 (308)

Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA

Journal of Extracellular Vesicles, 2022
One of the functions of small extracellular vesicles (sEVs) which has received the most attention is their capacity to deliver RNA into the cytoplasm of target cells.
Jenna McCann, Carmen Daniela Sosa‐Miranda, Huishan Guo, Ryan Reshke, Alexandre Savard, Adriana Zardini Buzatto, James A. Taylor, Liang Li, Derrick J. Gibbings   +8 more
doaj   +1 more source

Vibrio gazogenes-dependent disruption of aflatoxin biosynthesis in Aspergillus flavus: the connection with endosomal uptake and hyphal morphogenesis

Frontiers in Microbiology, 2023
Aflatoxins, a family of fungal secondary metabolites, are toxic and carcinogenic compounds that pose an enormous threat to global food safety and agricultural sustainability.
Rubaiya Jesmin, Jeffrey W. Cary, Matthew D. Lebar, Rajtilak Majumdar, Phani M. Gummadidala, Travis Dias, Savannah Chandler, Paramita Basu, Alan W. Decho, Nancy P. Keller, Anindya Chanda   +10 more
doaj   +1 more source

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function [PDF]

, 2011
Cholesterol regulates plasma membrane (PM) association and functioning of syntaxin-4 and soluble N-ethylmaleimide-sensitive fusion protein 23 (SNAP23) in the secretory pathway.
Enrich Bastús, Carles, Tebar Ramon, Francesc, Reverter Martín, Meritxell, Rentero Alfonso, Carles, Meritxell Reverter, Mulay, Vishwaroop, Peta Wood, Vilà de Muga, Sandra, Álvarez-Guaita, Anna, Anna Alvarez-Guaita, Albert Pol, Francesc Tebar, Carlos Enrich, Cairns, Rose, Joan Blasi, Blasi Cabús, Joan, Carles Rentero, Vishwaroop Mulay, Rose Cairns, Wood, Peta, Katia Monastyrskaya, Grewal, Thomas, Pol i Sorolla, Albert, Thomas Grewal, Monastyrskaya, Katia, Sandra Vilà de Muga   +25 more
core   +1 more source

Cellular localization, accumulation and trafficking of double-walled carbon nanotubes in human prostate cancer cells [PDF]

, 2012
Carbon nanotubes (CNTs) are at present being considered as potential nanovectors with the ability to deliver therapeutic cargoes into living cells. Previous studies established the ability of CNTs to enter cells and their therapeutic utility, but an ...
Silva, S. Ravi P., Coley, Helen M., Neves, V, Flahaut, E, Gerondopoulos, Andreas, Heister, Elena, Neves, Vera, Tîlmaciu, Carmen, Coley, HM, Flahaut, Emmanuel, Gerondopoulos, A, Heister, E, McFadden, J, McFadden, Johnjoe, Soula, Brigitte, Soula, B, Tîlmaciu, C, Silva, SRP   +17 more
core   +1 more source

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network [PDF]

, 2008
The small-molecule inhibitor Exo2 {4-hydroxy-3-methoxy-(5,6,7,8-tetrahydrol[1]benzothieno[2,3-d]pyrimidin-4-yl)hydraz-one benzaldehyde} has been reported to disrupt the Golgi apparatus completely and to stimulate Golgi–ER (endoplasmic reticulum) fusion ...
Amessou, M, Boal, Frédéric, Mohammed, Ludger, Roberts, LM, Stephens, David J, Smith, Daniel C., Clarkson, GJ, Stephens, D. J., Lord, JM, Clarkson, Guy J., Clarkson, Guy J, Roberts, Lynne M, Amessou, M., Watson, Peter D, Lord, J. M., Watson, Peter, Roberts, L. M. (Lynne M.), Amessou, Mohammed, Spooner, Robert A, Boal, F., Johannes, L., Smith, D. C., Smith, Daniel C, Clarkson, G. J., Spooner, Robert A., Stephens, David J., Watson, P, Smith, DC, Lord, J. Michael, Johannes, Ludger, Lord, Mike, Johannes, L, Spooner, RA, Boal, F, Stephens, DJ, Spooner, R. A., Watson, Peter Duncan, Roberts, L. M.   +37 more
core   +1 more source

Auxin Signaling in Regulation of Plant Translation Reinitiation

Frontiers in Plant Science, 2017
The mRNA translation machinery directs protein production, and thus cell growth, according to prevailing cellular and environmental conditions. The target of rapamycin (TOR) signaling pathway—a major growth-related pathway—plays a pivotal role in ...
Mikhail Schepetilnikov, Lyubov A. Ryabova   +1 more
doaj   +1 more source

Recycling endosomes [PDF]

Current Opinion in Cell Biology, 2015
The endosomal membrane recycling system represents a dynamic conduit for sorting and re-exporting internalized membrane constituents. The recycling system is composed of multiple tubulovesicular recycling pathways that likely confer distinct trafficking pathways for individual cargoes.
openaire   +2 more sources

Vaccinia Virus Infection Requires Maturation of Macropinosomes. [PDF]

, 2015
The prototypic poxvirus, vaccinia virus (VACV), occurs in two infectious forms, mature virions (MVs) and extracellular virions (EVs). Both enter HeLa cells by inducing macropinocytic uptake.
Mercer, Jason, Rizopoulos, Zaira, Balistreri, G, Kilcher, S, Mercer, J, Syedbasha, M, Kilcher, Samuel, Helenius, Ari, Balistreri, Giuseppe, Rizopoulos, Z, Syedbasha, Mohammedyaseen, Martin, Caroline K., Martin, CK, Helenius, A   +13 more
core   +1 more source

Dynamics of lysosomal cholesterol in Niemann-Pick type C and normal human fibroblasts

Journal of Lipid Research, 2002
The dynamics of endolysosomal cholesterol were investigated in Niemann-Pick type C (NPC) cells and in human fibroblasts treated with class 2 amphiphiles to mimic NPC cells.
Yvonne Lange, Jin Ye, Mike Rigney, Theodore L. Steck   +3 more
doaj   +1 more source

Rab2 drives axonal transport of dense core vesicles and lysosomal organelles

Cell Reports, 2021
Summary: Fast axonal transport of neuropeptide-containing dense core vesicles (DCVs), endolysosomal organelles, and presynaptic components is critical for maintaining neuronal functionality.
Viktor Karlovich Lund, Matthew Domenic Lycas, Anders Schack, Rita Chan Andersen, Ulrik Gether, Ole Kjaerulff   +5 more
doaj   +1 more source