Movies of fluorescently labelled late endosomes acquired in living ...
Francesco Cardarelli (249459) +5 more
core +1 more source
Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters
Transport between the endoplasmatic reticulum, the Golgi-network, the endo-lysosomal system and the cell surface can be categorized as anterograde or retrograde, describing traffic that goes forward or backward, respectively.
Stine C. Klinger +2 more
doaj +1 more source
Current Knowledge of Endolysosomal and Autophagy Defects in Hereditary Spastic Paraplegia
Hereditary spastic paraplegia (HSP) refers to a group of neurological disorders involving the degeneration of motor neurons. Due to their clinical and genetic heterogeneity, finding common effective therapeutics is difficult.
Liriopé Toupenet Marchesi +2 more
doaj +1 more source
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Falguières, Thomas +15 more
core +1 more source
Exosomal sorting of the viral oncoprotein LMP1 is restrained by TRAF2 association at signalling endosomes [PDF]
The Epstein–Barr virus (EBV)-encoded oncoprotein latent membrane protein 1 (LMP1) constitutively activates nuclear factor κB (NFκB) from intracellular membranes to promote cell growth and survival. LMP1 associates with CD63 in intracellular membranes and
Frederik J. Verweij +8 more
doaj +1 more source
Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast Moving Endosomes
Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport.
Nickolay Korabel +6 more
doaj +1 more source
Presynaptic endosomes are intracellular organelles involved in the recycling and degradation of receptors and membrane proteins. They also play a role in maintaining the pool of synaptic vesicles and in the recycling of dense-core vesicle membranes ...
R. Fernández-Chacón +3 more
core +1 more source
RETRACTED: Role of Protein VII in the Production of Infectious Bovine Adenovirus-3 Virion
Bovine adenovirus (BAdV)-3 genome encodes a 26 kDa core protein designated as protein VII, which localizes to the nucleus/nucleolus. The requirement of a protein VII-complementing cell line for the replication of VII-deleted BAdV-3 suggests that protein ...
Shermila Kulanayake +3 more
doaj +1 more source
Revisiting the Role of Clathrin-Mediated Endoytosis in Synaptic Vesicle Recycling
Without robust mechanisms to efficiently form new synaptic vesicles (SVs), the tens to hundreds of SVs typically present at the neuronal synapse would be rapidly used up, even at modest levels of neuronal activity.
Ira Milosevic
doaj +1 more source
Rab7 Associates with Early Endosomes to Mediate Sorting and Transport of Semliki Forest Virus to Late Endosomes [PDF]
Semliki forest virus (SFV) is internalized by clathrin-mediated endocytosis, and transported via early endosomes to late endosomes and lysosomes. The intracellular pathway taken by individual fluorescently labeled SFV particles was followed using ...
Andreas Vonderheit (124) +1 more
core +3 more sources

