Results 41 to 50 of about 107,252 (310)

Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast Moving Endosomes

open access: yesEntropy, 2021
Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport.
Nickolay Korabel   +6 more
doaj   +1 more source

Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]

open access: yes, 2007
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Falguières, Thomas   +15 more
core   +1 more source

IRAP Endosomes Control Phagosomal Maturation in Dendritic Cells

open access: yes, 2020
International audienceDendritic cells (DCs) contribute to the immune surveillance by sampling their environment through phagocytosis and endocytosis. We have previously reported that, rapidly following uptake of extracellular antigen into phagosomes or ...
Weimershaus, Mirjana   +5 more
core   +1 more source

RETRACTED: Role of Protein VII in the Production of Infectious Bovine Adenovirus-3 Virion

open access: yesViruses
Bovine adenovirus (BAdV)-3 genome encodes a 26 kDa core protein designated as protein VII, which localizes to the nucleus/nucleolus. The requirement of a protein VII-complementing cell line for the replication of VII-deleted BAdV-3 suggests that protein ...
Shermila Kulanayake   +3 more
doaj   +1 more source

Revisiting the Role of Clathrin-Mediated Endoytosis in Synaptic Vesicle Recycling

open access: yesFrontiers in Cellular Neuroscience, 2018
Without robust mechanisms to efficiently form new synaptic vesicles (SVs), the tens to hundreds of SVs typically present at the neuronal synapse would be rapidly used up, even at modest levels of neuronal activity.
Ira Milosevic
doaj   +1 more source

Synaptic Endosomes

open access: yes, 2006
Endosomes are important functional elements of the chemical synapse. They are used in membrane trafficking pathways controlling recycling and degradation of pre- and post-synaptic membrane proteins.
Shupliakov, O,, Haucke, V
core   +1 more source

Guiding Endosomal Maturation [PDF]

open access: yesCell, 2010
In the endocytic pathway, early endosomes are converted into late endosomes by exchange of their associated Rab GTPases. In this issue, Poteryaev et al. (2010) identify the SAND-1/Mon1 protein as a switch that shuts off the recruitment of one Rab (Rab5) and facilitates the activation of the next (Rab7).
Cabrera, Margarita, Ungermann, Christian
openaire   +2 more sources

Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways [PDF]

open access: yes, 2007
Rab family guanosine triphosphatases (GTPases) together with their regulators define specific pathways of membrane traffic within eukaryotic cells. In this study, we have investigated which Rab GTPase-activating proteins (GAPs) can interfere with the ...
Evelyn Fuchs   +18 more
core   +1 more source

FERARI and cargo adaptors coordinate cargo flow through sorting endosomes [PDF]

open access: yes, 2021
Cellular organization, compartmentalization and cell-to-cell communication are crucially dependent on endosomal pathways. Sorting endosomes provide a transit point for various trafficking pathways and decide the fate of proteins: recycling, secretion or ...
Solinger, Jachen A.   +3 more
core   +1 more source

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function

open access: yes, 2011
Cholesterol regulates plasma membrane (PM) association and functioning of syntaxin-4 and soluble N-ethylmaleimide-sensitive fusion protein 23 (SNAP23) in the secretory pathway.
Enrich Bastús, Carles   +25 more
core   +1 more source

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