Results 31 to 40 of about 155,580 (293)

Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast Moving Endosomes

open access: yesEntropy, 2021
Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport.
Nickolay Korabel   +6 more
doaj   +1 more source

Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]

open access: yes, 2007
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Amessou, Mohamed   +7 more
core   +1 more source

RETRACTED: Role of Protein VII in the Production of Infectious Bovine Adenovirus-3 Virion

open access: yesViruses
Bovine adenovirus (BAdV)-3 genome encodes a 26 kDa core protein designated as protein VII, which localizes to the nucleus/nucleolus. The requirement of a protein VII-complementing cell line for the replication of VII-deleted BAdV-3 suggests that protein ...
Shermila Kulanayake   +3 more
doaj   +1 more source

Revisiting the Role of Clathrin-Mediated Endoytosis in Synaptic Vesicle Recycling

open access: yesFrontiers in Cellular Neuroscience, 2018
Without robust mechanisms to efficiently form new synaptic vesicles (SVs), the tens to hundreds of SVs typically present at the neuronal synapse would be rapidly used up, even at modest levels of neuronal activity.
Ira Milosevic
doaj   +1 more source

A cell-based assay for CD63-containing extracellular vesicles [PDF]

open access: yes, 2019
Extracellular vesicles (EVs) are thought to be important in cell-cell communication and have elicited extraordinary interest as potential biomarkers of disease. However, quantitative methods to enable elucidation of mechanisms underlying release are few.
Cashikar, Anil G, Hanson, Phyllis I
core   +2 more sources

Endosome and INPP4B

open access: yesOncotarget, 2015
Phosphoinositide 3-kinase (PI3K) and AKT define a signaling network that regulates important biological processes such as cell cycle, survival, metabolism and motility, all of which are disrupted in cancer (Figure ​(Figure1)1) [1]. Hyperactivation of PI3K leads to increased production of phosphoinositide (PI) species such as PI(3,4,5)P3 and PI(3,4)P2 ...
Chew, Chen Li   +2 more
openaire   +2 more sources

Revisiting the Endocytosis of the M2 Muscarinic Acetylcholine Receptor

open access: yesMembranes, 2015
The agonist-induced endocytosis of the muscarinic acetylcholine receptor M2 is different from that of the other members of the muscarinic receptor family.
Wymke Ockenga, Ritva Tikkanen
doaj   +1 more source

Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine [PDF]

open access: yes, 2012
The neonatal Fc receptor (FcRn) transports maternal immunoglobulin (IgG) across epithelia to confer passive immunity to mammalian young. In newborn rodents, FcRn transcytoses IgG from ingested milk across the intestinal epithelium for release into the ...
Bjorkman, Pamela J.   +2 more
core   +2 more sources

Inhibition of early EHDV2-Ibaraki infection steps in bovine cells by endosome alkalinization or ikarugamycin, but not by blockage of individual endocytic pathways

open access: yesFrontiers in Cellular and Infection Microbiology
The Epizootic hemorrhagic disease virus (EHDV), an orbivirus, is the etiological factor of a fatal hemorrhagic disease of wild ruminants. A subset of EHDV serotypes, including the Ibaraki strain of EHDV2 (EHDV2-Ibaraki), infect and cause disease in ...
Maya Malka   +5 more
doaj   +1 more source

Changes in membrane lipids drive increased endocytosis following Fas ligation [PDF]

open access: yes, 2017
Once activated, some surface receptors promote membrane movements that open new portals of endocytosis, in part to facilitate the internalization of their activated complexes.
Degli Esposti, Mauro   +9 more
core   +1 more source

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