Results 91 to 100 of about 571,172 (234)
Large-scale molecular dynamics simulation of coupled dynamics of flow and glycocalyx: towards understanding atomic events on an endothelial cell surface [PDF]
, 2017 The glycocalyx has a prominent role in orchestrating multiple biological processes occurring at the plasma membrane. In this paper, an all-atom flow/glycocalyx system is constructed with the bulk flow velocity in the physiologically relevant ranges for ...
Gong, H, Jiang, XZ, Luo, KH, Ventikos, Y
core +1 more source
Vascular Endothelial Glycocalyx Damage in COVID-19
International Journal of Molecular Sciences, 2020 The new coronavirus disease-2019 (COVID-19), which is spreading around the world and threatening people, is easily infecting a large number of people through airborne droplets; moreover, patients with hypertension, diabetes, obesity, and cardiovascular ...
M. Yamaoka-Tojo
semanticscholar +1 more source
Journal of Neuroinflammation, 2021 Traumatic brain injury (TBI) remains one of the leading causes of death and disability worldwide; more than 10 million people are hospitalized for TBI every year around the globe.
Zhimin Zou +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour +14 more
wiley +1 more source
Multi-scale interaction of flow and the artery wall [PDF]
, 2009 We discuss, from the perspective of basic science, the physical and biological processes which underlie atherosclerotic (plaque) initiation at the vascular endothelium, identifying their widely separated spatial and temporal scales which participate.
2nd Micro and Nano Flows Conference (MNF2009) +15 more
core
PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity
Advanced Science, EarlyView.Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley +1 more source
Microcirculatory blood flow: Functional implications of a complex fluid [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011) +3 more
core
Endothelial barrier dysfunction in diabetic conduit arteries: a novel method to quantify filtration [PDF]
, 2012 The endothelial barrier plays an important role in atherosclerosis, hyperglycemia, and hypercholesterolemia. In the present study, an accurate, reproducible, and user-friendly method was used to further understand endothelial barrier function of conduit ...
Huxley, Virginia H. +2 more
core +1 more source
Microcirculation, 2020 The potential for a rapid increase in severity is among the most frightening aspects of severe acute respiratory syndrome coronavirus 2 infection. Evidence increasingly suggests that the symptoms of coronavirus disease‐2019 (COVID‐19)‐related acute ...
Hideshi Okada +4 more
semanticscholar +1 more source
Journal of Neuroinflammation, 2021 Background Traumatic brain injury (TBI) remains one of the main causes for disability and death worldwide. While the primary mechanical injury cannot be avoided, the prevention of secondary injury is the focus of TBI research.
Zhimin Zou +8 more
semanticscholar +1 more source