Results 11 to 20 of about 3,316 (159)

Bispecific self-assembled peptides as supra-growth factors for preventing endotheliopathy and improving survival of traumatic brain injury in mice [PDF]

Journal of Nanobiotechnology
Traumatic brain injury (TBI) causes endothelial injury (endotheliopathy), which contributes to a cascade of adverse events, including cerebral hemorrhage, edema and acute lung injury (ALI), and leads to poor clinical outcomes.
Yichi Zhang, Lanxing Wang, Dandan Li, Xingyao Sun, Zijian Zhou, Ying Zhang, Linan Jiao, Shuhong Yang, Yafan Liu, Tianrui Ma, Hao Zhang, Lujia Tang, Kaifeng Pang, Pengbo Zhao, Muyan Xu, Jie Li, Jianning Zhang, Zhimou Yang, Jie Gao, Zilong Zhao   +19 more
doaj   +2 more sources

Microcirculatory perfusion is improved with plasma, but not with crystalloids, in a rat polytraumatic shock model. [PDF]

Transfusion
Abstract Background Traumatic shock is associated with microcirculatory dysfunction. Plasma resuscitation for traumatic shock outside the context of bleeding may exert benefit by augmenting intravascular volume and inhibiting endotheliopathy. However, its effects on microcirculatory perfusion and tissue oxygenation in trauma remain poorly understood ...
Gözden T, Ergin B, Ince C, Juffermans NP.   +3 more
europepmc   +2 more sources

Concomitant Traumatic Brain Injury Exacerbates Endotheliopathy in Patients with Spinal Cord Injury [PDF]

Neurotrauma Reports
Neurotrauma can cause endothelial dysfunction, characterized by neurovascular barrier disruption, tissue edema, neuroinflammation, and coagulation abnormalities, all of which may contribute to secondary injuries and worsened clinical outcomes.
Shahab Hafezi, Miguel A. Ruiz-Cardozo, Sarbani Ghosh, Sravanthi Bandla, Matthew N. Montoya Rush, Anand Dharmarajan, Mark H. Hoofnagle, Isaiah R. Turnbull, Camilo A. Molina, Grace M. Niziolek   +9 more
doaj   +2 more sources

Endotheliopathy in Acute COVID-19 and Long COVID

International Journal of Molecular Sciences, 2023
The pulmonary endothelium is a highly regulated organ that performs a wide range of functions under physiological and pathological conditions. Since endothelial dysfunction has been demonstrated to play a direct role in sepsis and acute respiratory distress syndrome, its role in COVID-19 has also been extensively investigated.
Stylianos Orfanos, Charikleia Vrettou, Ioanna Dimopoulou   +2 more
exaly   +4 more sources

Vaccine-Associated Thrombocytopenia and Thrombosis: Venous Endotheliopathy Leading to Venous Combined Micro-Macrothrombosis

Medicina (Lithuania), 2021
Serious vaccine-associated side effects are very rare. Major complications of vaccines are thrombocytopenia and thrombosis in which pathogenetic mechanism is consistent with endotheliopathy characterized by “attenuated” sepsis-like syndrome, leading to ...
Jae Chang, Harrison Hawley
exaly   +3 more sources

Beauty, Bias, and Beyond: The Role of Artificial Intelligence in Aesthetic Medicine. [PDF]

J Cosmet Dermatol
Journal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
Knoedler SA, Alfertshofer M, Bravo BSF, Sofo G, Mazzarone F, Gaudin R, Sailer HF, Lellouch AG, Knoedler L.   +8 more
europepmc   +2 more sources

Endothelial thrombomodulin-Its role in trauma-induced coagulopathy. [PDF]

Transfusion
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Abu-Hanna J, Morrow GB, Xu G, Timms L, Akbar N, Laffan M, Choudhury RP, Curry N.   +7 more
europepmc   +2 more sources

Case Report: Endothelial-targeted bridging therapy for a TTP-like phenotype in fulminant iMCD-TAFRO [PDF]

Frontiers in Immunology
BackgroundiMCD-TAFRO (the TAFRO clinical subtype of idiopathic multicentric Castleman disease (iMCD)) is characterized by thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly.
Jing Du, Liangliang Wu, Haigang Li, Haibo Gan, Tao Yu, Shuangfeng Xie, Xiangshao Fang   +6 more
doaj   +2 more sources

Plasma PF4 is a reliable biomarker of platelet reactivity and predictive of bleeding risk in DAPT patients undergoing cardiac surgery [PDF]

Thrombosis Journal
Background Platelet activation is crucial for hemostasis and thrombosis, particularly in patients on antiplatelet therapy. Managing bleeding risk during cardiac surgery requires understanding platelet dynamics, especially when antiplatelet agents are ...
Joseph Roux de Bezieux, Julien Amour, Aurélien Philippe, Jeanne Rancic, Nicolas Gendron, Sébastien Bertil, Marc Garnier, Pascale Gaussem, David M. Smadja   +8 more
doaj   +2 more sources

m-EASIX (better than EASIX) predicts severe CAR T-cell toxicities, worse overall survival, and discriminates cytokine release syndrome from sepsis [PDF]

Frontiers in Immunology
BackgroundCytokine Release Syndrome (CRS) and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) are life-threatening complications that often arise after CAR T-cell immunotherapy. Endothelial dysfunction is believed to play a central role in
Ana Belén Moreno-Castaño, Ana Belén Moreno-Castaño, Ana Belén Moreno-Castaño, Sara Fernández, Sara Fernández, Sara Fernández, Helena Brillembourg, Gontzal Iraola, David F Moreno, Helena Ventosa-Capell, Helena Ventosa-Capell, Julia Martinez-Sanchez, Julia Martinez-Sanchez, Blanca De Moner, Blanca De Moner, Blanca De Moner, Patricia Molina, Alex Ramos, Marta Palomo, Pilar Gómez-Ramírez, Valentín Ortiz-Maldonado, Nuria Martínez-Cibrián, Julio Delgado, Julio Delgado, Julio Delgado, Aina Oliver-Caldés, Aina Oliver-Caldés, Carlos Fernández de Larrea, Carlos Fernández de Larrea, Carlos Fernández de Larrea, María Queralt Salas, Álvaro Urbano, Álvaro Urbano, Álvaro Urbano, Adrián Téllez, José María Nicolás, José María Nicolás, Manel Juan, Azucena González-Navarro, Olaf Penack, Gines Escolar, Gines Escolar, Gines Escolar, Enric Carreras, Francesc Fernández-Avilés, Francesc Fernández-Avilés, Francesc Fernández-Avilés, Pedro Castro, Pedro Castro, Pedro Castro, Maribel Diaz-Ricart, Maribel Diaz-Ricart, Maribel Diaz-Ricart   +52 more
doaj   +2 more sources