Results 1 to 10 of about 27,102 (124)
PAKing up to the endothelium [PDF]
Cellular Signalling, 2009 Angiogenesis recapitulates the growth of blood vessels that progressively expand and remodel into a highly organized and stereotyped vascular network. During adulthood, endothelial cells that formed the vascular wall retain their plasticity and can be engaged in neo-vascularization in response to physiological stimuli, such as hypoxia, wound healing ...
Eva Maria Galan Moya +4 more
arxiv +7 more sources
Vascular Biology, 2021 Cellular senescence is now recognized as one of the hallmarks of aging. Herein, we examine current findings on senescence of the vascular endothelium and its impacts on age-related vascular diseases. Endothelial senescence can result in systemic metabolic changes, implicating senescence in chronic diseases such as diabetes, obesity and atherosclerosis.
Paul R. Coleman +4 more
openaire +2 more sources
The Endothelium in Sepsis [PDF]
Shock, 2016 Sepsis affects practically all aspects of endothelial cell (EC) function and is thought to be the key factor in the progression from sepsis to organ failure. Endothelial functions affected by sepsis include vasoregulation, barrier function, inflammation, and hemostasis.
Ince, Can +8 more
openaire +7 more sources
The Endothelium in Acromegaly [PDF]
Frontiers in Endocrinology, 2019 Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known deleterious effects on the cardiovascular system, especially after long-term exposition. Acromegaly, a condition of chronic GH and IGF-1 hypersecretion, is frequently associated to cardiovascular complications, although recent studies have shown a reduction in the ...
Maffei, Pietro +4 more
openaire +4 more sources
The artificial endothelium [PDF]
Organogenesis, 2011 As the world of critical care medicine advances, extracorporeal therapies (ECC) have become commonplace in the management of the high risk intensive care patient. ECC encompasses a wide variety of technologies from hemodialysis, continuous renal replacement therapy (CRRT) and plasmapheresis, to cardiopulmonary bypass (CPB), extracorporeal life support (
Melissa M. Reynolds, Gail M. Annich
openaire +3 more sources
Immersed boundary simulations of cell-cell interactions in whole blood [PDF]
, 2021 We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial basis functions for high-order meshless parametric reconstruction of point clouds and the elastic force computations
arxiv +1 more source
Physiology of the endothelium [PDF]
British Journal of Anaesthesia, 2004 In the past, the endothelium was considered to be inert, described as a 'layer of nucleated cellophane', with only non-reactive barrier properties, such as presentation of a non-thrombogenic surface for blood flow and guarding against pro-inflammatory insults.
Nigel R. Webster, Helen F. Galley
openaire +3 more sources
Pressure-driven wrinkling of soft inner-lined tubes [PDF]
Volume 24, 2022, 013026, 2021 Wrinkling of an inextensible elastic lining of an inner-lined tube under imposed pressure is considered. A simple equation modeling the elastic properties of the lining, the pressure, and the soft-substrate forces is derived. This equation aims to capture the wrinkling response of arterial endothelium to blood pressure changes.
arxiv +1 more source
Eye, 1990 The endothelium is a monolayer of cells on the posterior corneal surface that transports water from the stroma into the anterior chamber. This movement of water counters a natural tendency for the stroma to swell and is necessary to maintain a transparent cornea.
Douglas J. Coster +2 more
openaire +2 more sources
Deciphering the relative contribution of vascular inflammation and blood rheology in metastatic spreading [PDF]
Biomicrofluidics 12.4 (2018), p. 042205. doi: 10.1063/1.5022879.
eprint: https://doi.org/10.1063/1. 5022879. url:
https://doi.org/10.1063/1.5022879, 2018 Vascular adhesion of circulating tumor cells (CTCs) is a key step in cancer spreading. If inflammation is recognized to favor the formation of vascular metastatic niches, little is known about the contribution of blood rheology to CTC deposition. Herein, a microfluidic chip, covered by a confluent monolayer of endothelial cells, is used for analyzing ...
arxiv +1 more source