Results 1 to 10 of about 554,909 (368)
PAKing up to the endothelium [PDF]
Angiogenesis recapitulates the growth of blood vessels that progressively expand and remodel into a highly organized and stereotyped vascular network. During adulthood, endothelial cells that formed the vascular wall retain their plasticity and can be engaged in neo-vascularization in response to physiological stimuli, such as hypoxia, wound healing ...
Armelle Le Guelte+3 more
arxiv +7 more sources
Aims Acute decompensated heart failure (ADHF), a live‐threatening complication of heart failure (HF), associates a further decrease of the already by HF‐impaired cardiac function with an increase in heart rate.
Nicolas Peschanski+15 more
doaj +1 more source
Effects of PCSK9 Targeting: Alleviating Oxidation, Inflammation, and Atherosclerosis
Characterized as a chronic inflammatory disease of the large arteries, atherosclerosis is the primary cause of cardiovascular disease, the leading contributor of morbidity and mortality worldwide.
Emily Punch+4 more
doaj +1 more source
Cellular senescence is now recognized as one of the hallmarks of aging. Herein, we examine current findings on senescence of the vascular endothelium and its impacts on age-related vascular diseases.
Ka Ka Ting+4 more
doaj +1 more source
Clinical differential diagnosis of arteriolosclerotic ulcers of Martorell is challenging due to the lack of clearly affirmative instrument-based diagnostic criteria.
Julia Deinsberger+11 more
doaj +1 more source
Background Vascular endothelial cell alignment in the direction of flow is an adaptive response that protects against aortic diseases such as atherosclerosis. The RhoGTPases are known to regulate this alignment.
Paul R. Coleman+7 more
doaj +1 more source
Reproducibility and research integrity: the role of scientists and institutions
Reproducibility and research integrity are essential tenets of every scientific study and discovery. They serve as proof that an established and documented work can be verified, repeated, and reproduced.
Patrick Diaba-Nuhoho+1 more
doaj +1 more source
Oxidative Stress, Antioxidants and Hypertension
As a major cause of morbidity and mortality globally, hypertension remains a serious threat to global public health. Despite the availability of many antihypertensive medications, several hypertensive individuals are resistant to standard treatments, and
Michael Amponsah-Offeh+3 more
doaj +1 more source
Immersed boundary simulations of cell-cell interactions in whole blood [PDF]
We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial basis functions for high-order meshless parametric reconstruction of point clouds and the elastic force computations
arxiv +1 more source
Cross-Talk of NADPH Oxidases and Inflammation in Obesity
Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz+6 more
doaj +1 more source