Results 1 to 10 of about 149 (149)
Vascular Biology, 2021 Cellular senescence is now recognized as one of the hallmarks of aging. Herein, we examine current findings on senescence of the vascular endothelium and its impacts on age-related vascular diseases. Endothelial senescence can result in systemic metabolic changes, implicating senescence in chronic diseases such as diabetes, obesity and atherosclerosis.
Paul R. Coleman +4 more
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The Endothelium in Sepsis [PDF]
Shock, 2016 Sepsis affects practically all aspects of endothelial cell (EC) function and is thought to be the key factor in the progression from sepsis to organ failure. Endothelial functions affected by sepsis include vasoregulation, barrier function, inflammation, and hemostasis.
Ince, Can +8 more
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The Endothelium in Acromegaly [PDF]
Frontiers in Endocrinology, 2019 Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known deleterious effects on the cardiovascular system, especially after long-term exposition. Acromegaly, a condition of chronic GH and IGF-1 hypersecretion, is frequently associated to cardiovascular complications, although recent studies have shown a reduction in the ...
Maffei, Pietro +4 more
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The artificial endothelium [PDF]
Organogenesis, 2011 As the world of critical care medicine advances, extracorporeal therapies (ECC) have become commonplace in the management of the high risk intensive care patient. ECC encompasses a wide variety of technologies from hemodialysis, continuous renal replacement therapy (CRRT) and plasmapheresis, to cardiopulmonary bypass (CPB), extracorporeal life support (
Melissa M. Reynolds, Gail M. Annich
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Physiology of the endothelium [PDF]
British Journal of Anaesthesia, 2004 In the past, the endothelium was considered to be inert, described as a 'layer of nucleated cellophane', with only non-reactive barrier properties, such as presentation of a non-thrombogenic surface for blood flow and guarding against pro-inflammatory insults.
Nigel R. Webster, Helen F. Galley
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Eye, 1990 The endothelium is a monolayer of cells on the posterior corneal surface that transports water from the stroma into the anterior chamber. This movement of water counters a natural tendency for the stroma to swell and is necessary to maintain a transparent cornea.
Douglas J. Coster +2 more
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Endothelium in Diseased States [PDF]
BioMed Research International, 2014 Endothelium is the endocrine organ essential for maintenance of homeostasis in the entire body. Endothelium operates by a broad spectrum of signaling molecules controlling the contractile state of vascular smooth muscles and cardiomyocytes; long distance intercellular synchronization within the vascular wall; adhesive, coagulant, and rheological ...
Bernátová, Iveta +3 more
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Biology of the Endothelium [PDF]
Clinical Cardiology, 1997 The endothelium releases factors that control vascular relaxation and contraction, thrombogenesis and fibrinolysis, and platelet activation and inhibition. Maintaining the functional integrity of the endothelium, therefore, is critical for the preservation of blood flow and the prevention of thrombosis.
Thomas F. Lüscher, Matthias Barton
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Endoglin: Beyond the Endothelium [PDF]
Biomolecules, 2020 Keywords: endoglin; CD105 TGF-β; BMP9; ALK-1; TRC105; tumor ...
Schoonderwoerd, M.J.A. +2 more
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Lipids and the endothelium [PDF]
Cardiovascular Research, 1999 The normal endothelium is characterised by the production of a number of molecules which affect the contractile state of adjacent myocytes and the behavior of formed elements within the blood stream, and by the absence of cell surface adhesion molecules. In addition, endothelial cells are important modulators of coagulation and fibrinolysis.
Jaye Chin-Dusting, Anthony M. Dart
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