Role of enkephalin derivative in promoting wound healing and scar remodeling via increased epidermal growth factor in a mouse model [PDF]
Archives of Aesthetic Plastic Surgery, 2023 Background Enkephalin, an endogenous neuropeptide, binds to the delta (δ) opioid receptor and exerts an antinociceptive effect. Recent studies have suggested that neuropeptides might effectuate cutaneous wound healing.
Sun Eung Kim +2 more
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Exposure to exogenous enkephalins disrupts reproductive development in the Eastern lubber grasshopper, Romalea microptera (Insecta: Orthoptera). [PDF]
PLoS ONE, 2012 Enkephalins play a major role in reproductive physiology in crustaceans; however their role in reproductive development in insects is largely unknown. We investigated the effect of exposure to exogenous leucine-enkephalin (Leu-Enk), methionine-enkephalin
Sandeep Kumar +4 more
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Active site mutations change the cleavage specificity of neprilysin. [PDF]
PLoS ONE, 2012 Neprilysin (NEP), a member of the M13 subgroup of the zinc-dependent endopeptidase family is a membrane bound peptidase capable of cleaving a variety of physiological peptides.
Travis Sexton +4 more
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Iraqi Journal of Pharmaceutical Sciences, 2017 A small number of researches were done in the design and synthesis of enkephalin analogues that are able to resist degradation effect of proteolytic enzymes with good bioavailability and half-lives.Through studying structure activity relationships we ...
Muthanna S. Al-Ttaee +2 more
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MALDI-induced fragmentation of leucine enkephalin, nitro-Tyr-leucine enkaphalin, and d5-Phe-nitro-Tyr-leucine enkephalin [PDF]
International Journal of Mass Spectrometry, 2009 The long-term objective of this study is to use MALDI MS and MS/MS to study the fragmentation pattern of in vitro nitrotyrosine-containing peptides in order to assist the interpretation of MS-identification of endogenous nitroproteins in human tissues and fluids.
Xianquan, Zhan, Dominic M, Desiderio
openaire +2 more sources
Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS). [PDF]
PLoS ONE, 2017 Azithromycin is recommended for the treatment of uncomplicated urogenital chlamydia infection although the standard 1gram dose sometimes fails to eradicate the infection (treatment failure).
Lenka A Vodstrcil +12 more
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Frontiers in Medical Technology, 2021 Tyrosine-arginine (kyotorphin), an opioid analgesic dipeptide, was discovered more than 40 years ago in 1979. The evidence accumulated during this period has established the physiological significance of kyotorphin as a neuromodulating peptide, and ...
Hiroshi Ueda, Hiroshi Ueda, Hiroshi Ueda
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Enkephalin Leucine Microspheres Suspension as a Sustained Antiplaque Antimicrobial Delivery System
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2010 The purpose of this study is to prepare a formulation containing enkephalin leucine as an antiplaque/antibacterial agent. Enkephalin leucine microspheres were prepared using a poly(D-L-lactide-co-glycolide) (PLGA) as a delivery system.
Laith H. Samein
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Scientific Reports, 2022 Porous silica particles were prepared by sol–gel method with some modification to get wide-pore particles. These particles were derivatized with N-phenylmaleimide-methylvinylisocyanate (PMI) and styrene by reversible addition fragmentation chain transfer
Sarah Alharthi +6 more
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Degradation of Multiple Peptides by Microcystin-Degrader Paucibacter toxinivorans (2C20)
Toxins, 2021 Since conventional drinking water treatments applied in different countries are inefficient at eliminating potentially toxic cyanobacterial peptides, a number of bacteria have been studied as an alternative to biological filters for the removal of ...
Allan A. Santos +6 more
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