Results 11 to 20 of about 126,781 (219)

Role of enkephalin derivative in promoting wound healing and scar remodeling via increased epidermal growth factor in a mouse model [PDF]

open access: yesArchives of Aesthetic Plastic Surgery, 2023
Background Enkephalin, an endogenous neuropeptide, binds to the delta (δ) opioid receptor and exerts an antinociceptive effect. Recent studies have suggested that neuropeptides might effectuate cutaneous wound healing.
Sun Eung Kim   +2 more
doaj   +1 more source

Exposure to exogenous enkephalins disrupts reproductive development in the Eastern lubber grasshopper, Romalea microptera (Insecta: Orthoptera). [PDF]

open access: yesPLoS ONE, 2012
Enkephalins play a major role in reproductive physiology in crustaceans; however their role in reproductive development in insects is largely unknown. We investigated the effect of exposure to exogenous leucine-enkephalin (Leu-Enk), methionine-enkephalin
Sandeep Kumar   +4 more
doaj   +1 more source

Active site mutations change the cleavage specificity of neprilysin. [PDF]

open access: yesPLoS ONE, 2012
Neprilysin (NEP), a member of the M13 subgroup of the zinc-dependent endopeptidase family is a membrane bound peptidase capable of cleaving a variety of physiological peptides.
Travis Sexton   +4 more
doaj   +1 more source

Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS). [PDF]

open access: yesPLoS ONE, 2017
Azithromycin is recommended for the treatment of uncomplicated urogenital chlamydia infection although the standard 1gram dose sometimes fails to eradicate the infection (treatment failure).
Lenka A Vodstrcil   +12 more
doaj   +1 more source

Comprehensive Analysis of Sinomenii caulis and Menispermi rhizoma Based on Ultra-High Performance Liquid Chromatography and Ultra-High Performance Liquid Chromatography-Quadrupole Time-of-Flight-Mass Spectrometry. [PDF]

open access: yesAnal Sci Adv
ABSTRACT Sinomenii caulis (SC) and Menispermi rhizoma (MR) are Chinese herbal medicines from the same family and are often confused. To achieve identification of SC and MR, the paper used the differential chemical components and the combination characteristics of chemical components to carry out a comprehensive analysis.
Tao Y   +9 more
europepmc   +2 more sources

Review of Kyotorphin Research: A Mysterious Opioid Analgesic Dipeptide and Its Molecular, Physiological, and Pharmacological Characteristics

open access: yesFrontiers in Medical Technology, 2021
Tyrosine-arginine (kyotorphin), an opioid analgesic dipeptide, was discovered more than 40 years ago in 1979. The evidence accumulated during this period has established the physiological significance of kyotorphin as a neuromodulating peptide, and ...
Hiroshi Ueda, Hiroshi Ueda, Hiroshi Ueda
doaj   +1 more source

Electroosmotic perfusion-microdialysis probe created by direct laser writing for quantitative assessment of leucine enkephalin hydrolysis by insulin-regulated aminopeptidase in vivo.

open access: yesAnalytical Chemistry, 2020
There are many processes that actively alter the concentrations of solutes in the extracellular space. Enzymatic reactions, either by soluble enzymes or membrane-bound ectoenzymes, and uptake or clearance are two such processes.
Rachael E. Wilson   +4 more
semanticscholar   +1 more source

Preparation of mixed-mode stationary phase for separation of peptides and proteins in high performance liquid chromatography

open access: yesScientific Reports, 2022
Porous silica particles were prepared by sol–gel method with some modification to get wide-pore particles. These particles were derivatized with N-phenylmaleimide-methylvinylisocyanate (PMI) and styrene by reversible addition fragmentation chain transfer
Sarah Alharthi   +6 more
doaj   +1 more source

Degradation of Multiple Peptides by Microcystin-Degrader Paucibacter toxinivorans (2C20)

open access: yesToxins, 2021
Since conventional drinking water treatments applied in different countries are inefficient at eliminating potentially toxic cyanobacterial peptides, a number of bacteria have been studied as an alternative to biological filters for the removal of ...
Allan A. Santos   +6 more
doaj   +1 more source

Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]

open access: yes, 2013
The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
Bongiorno, David   +7 more
core   +2 more sources

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