Results 21 to 30 of about 20,144 (188)

A trigeminoreticular pathway: implications in pain. [PDF]

PLoS ONE, 2011
Neurons in the caudalmost ventrolateral medulla (cmVLM) respond to noxious stimulation. We previously have shown most efferent projections from this locus project to areas implicated either in the processing or modulation of pain.
W Michael Panneton, Qi Gan, Robert S Livergood   +2 more
doaj   +1 more source

Actions of D-Ala2-D-Leu5-enkephalin and dynorphin A (1–17) on neocortical neurons in vitro [PDF]

, 1984
Intracellular recordings were made from neocortical neurons in vitro. Application of D-Ala2-D-Leu5-enkephalin (DADL) by different methods produced a decrease in EPSP amplitude and in the amplitude of L-glutamate-induced depolarizations without changes in
B Sutor, Khachaturian, Lewis, Quirion, Satoh, W Zieglgänsberger, Weber, Williams, Williams, Yoshimura, Zieglgänsberger, Zieglgänsberger   +11 more
core   +1 more source

Effects of Leucine-enkephalin on Catalase Activity and Hydrogen Peroxide Levels in the Haemolymph of the Pacific Oyster (Crassostrea gigas)

Molecules, 2008
The nervous and immune systems of invertebrates can exchange informationthrough neuropeptides. Furthermore, some opioid peptides can function as endogenousimmune system messengers and participate in the regulation of the immune responses.
Hong-zhi Xu, Zhi-wei Chen, Dong-wu Liu
doaj   +1 more source

NADPH oxidase as a therapeutic target in Alzheimer\u27s disease [PDF]

, 2008
At present, available treatments for Alzheimer\u27s disease (AD) are largely unable to halt disease progression. Microglia, the resident macrophages in the brain, are strongly implicated in the pathology and progressively degenerative nature of AD ...
Block, Michelle L
core   +4 more sources

The Non-Human Primate Striatum Undergoes Marked Prolonged Remodeling during Postnatal Development

Frontiers in Cellular Neuroscience, 2014
We examined the postnatal ontogeny of the striatum in rhesus monkeys (Macaca mulatta) to identify temporal and spatial patterns of histological and chemical maturation.
Lee J Martin, Linda C Cork
doaj   +1 more source

The influence of experimental inflammation and axotomy on leucine enkephalin (leuENK) distribution in intramural nervous structures of the porcine descending colon

BMC Veterinary Research, 2018
Background The enteric nervous system (ENS), located in the intestinal wall and characterized by considerable independence from the central nervous system, consists of millions of cells.
Slawomir Gonkowski, Krystyna Makowska, Jaroslaw Calka   +2 more
doaj   +1 more source

Photodissociation spectroscopy of protonated leucine enkephalin

Physical Chemistry Chemical Physics, 2017
The protonated pentapeptide leucine enkephaline (YGGFL) fragments upon absorption of multiple UV photons by the tyrosine chromophore, providing complete sequence coverage.
Andreas Herburger, Christian van der Linde, Martin K. Beyer   +2 more
openaire   +3 more sources

Direct peptide bioconjugation/PEGylation at tyrosine with linear and branched polymeric diazonium salts [PDF]

, 2012
Direct polymer conjugation at peptide tyrosine residues is described. In this study Tyr residues of both leucine enkephalin and salmon calcitonin (sCT) were targeted using appropriate diazonium salt-terminated linear monomethoxy poly(ethylene glycol)s ...
Aghemo A., Aurora J., Ban H., Brocchini S., Brown J. P., Canevari M., Chesnut C. H., Claudia A. Blindauer, Curreli N., David J. Brayden, David M. Haddleton, DeTraglia M. C., Duncan R., Edgcomb S. P., Epand R. M., Espuna G., Fishburn C. S., Gao W., Giuseppe Mantovani, Gorecki M., Hooker J. M., Howard A. N., Jain A., Jain R. K., Joshi N. S., Kato M., Kopecek J., Kopecek J., Lecolley F., Lee K. C., Lele B. S., Lele B. S., Li K., Magnusson J. P., Mantovani G., Mathew W. Jones, McFarland J. M., Ouchi M., Patai S., Patai S., Pauly H. Z., Rafii F., Roberts M. J., Romanini D. W., Ryan S. M., Sams C. F., Sayers C. T., Sayers C. T., Schalk I., Schlick T. L., Sinead M. Ryan, Southam R. M., Szurdoki F., Tao L., Tilley S. D., Tracey B. M., Vaughan K., Veronese F. M., Vilaro M., Wang J.-S., White E. H., Wong S. S., Xuexuan Wang, Yasayan G., Zloh M.   +64 more
core   +1 more source

Neuroprotective and neuroregenerative potential of pharmacologically-induced hypothermia with D-alanine D-leucine enkephalin in brain injury

Neural Regeneration Research, 2018
Neurovascular disorders, such as traumatic brain injury and stroke, persist as leading causes of death and disability – thus, the search for novel therapeutic approaches for these disorders continues.
M Grant Liska, Marci G Crowley, Julian P Tuazon, Cesar V Borlongan   +3 more
doaj   +1 more source

Methionine-enkephalin and leucine-enkephalin in human sympathoadrenal system and pheochromocytoma. [PDF]

Journal of Clinical Investigation, 1982
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with ...
T, Yoshimasa, K, Nakao, H, Ohtsuki, S, Li, H, Imura   +4 more
openaire   +2 more sources