Results 31 to 40 of about 10,678 (183)

Acetaldehyde‐enkephalins: pronounced changes in the opiate activity of methionine‐enkephalin and leucine‐enkephalin on reaction with acetaldehyde [PDF]

FEBS Letters, 1980
We have shown that the two major endogenous opioid peptides, methionine-enkephalin and leucineenkephalin [ 1,2] (enkephalin [Met’] and enkephalin[Leu’]) rapidly react with acetaldehyde in aqueous buffers to give a stable ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin[Met’]’ and ‘acetaldehyde-enkephalin [Leu’]‘, respectively ...
Roger J. Hayes, Michael C. Summers
openaire   +3 more sources

The influence of experimental inflammation and axotomy on leucine enkephalin (leuENK) distribution in intramural nervous structures of the porcine descending colon

BMC Veterinary Research, 2018
Background The enteric nervous system (ENS), located in the intestinal wall and characterized by considerable independence from the central nervous system, consists of millions of cells.
Slawomir Gonkowski, Krystyna Makowska, Jaroslaw Calka   +2 more
doaj   +1 more source

Plasma leucine enkephalin is increased in liver disease. [PDF]

Gut, 1989
Plasma methionine enkephalin is increased in liver disease and may contribute to some of the clinical manifestations of hepatic failure. To determine if another 'small' opioid peptide is increased in the plasma of patients with liver disease, leucine enkephalin was measured by radioimmunoassay.
M S Losowsky, J R Thornton
openaire   +3 more sources

New analogues of leucine-methionine-enkephalin

Journal of Biosciences, 1988
Nine analogues of the opioid pentapeptides leucine-/ methionine-enkephalinamide, involving replacement of amino acid at position 5 or amino acids at positions 2 and 5, have been synthesized by the solid phase method using mainly 9-fluorenylmethyloxycarbonyl amino acid trichlorophenyl esters in the presence of 1-hydroxybenzotriazole, the solid support ...
Sivanandaiah, K.M., Gurusiddappa, S., Channegowda, C.   +2 more
openaire   +3 more sources

Neuroprotective and neuroregenerative potential of pharmacologically-induced hypothermia with D-alanine D-leucine enkephalin in brain injury

Neural Regeneration Research, 2018
Neurovascular disorders, such as traumatic brain injury and stroke, persist as leading causes of death and disability – thus, the search for novel therapeutic approaches for these disorders continues.
M Grant Liska, Marci G Crowley, Julian P Tuazon, Cesar V Borlongan   +3 more
doaj   +1 more source

Direct peptide bioconjugation/PEGylation at tyrosine with linear and branched polymeric diazonium salts [PDF]

, 2012
Direct polymer conjugation at peptide tyrosine residues is described. In this study Tyr residues of both leucine enkephalin and salmon calcitonin (sCT) were targeted using appropriate diazonium salt-terminated linear monomethoxy poly(ethylene glycol)s ...
Aghemo A., Aurora J., Ban H., Brocchini S., Brown J. P., Canevari M., Chesnut C. H., Claudia A. Blindauer, Curreli N., David J. Brayden, David M. Haddleton, DeTraglia M. C., Duncan R., Edgcomb S. P., Epand R. M., Espuna G., Fishburn C. S., Gao W., Giuseppe Mantovani, Gorecki M., Hooker J. M., Howard A. N., Jain A., Jain R. K., Joshi N. S., Kato M., Kopecek J., Kopecek J., Lecolley F., Lee K. C., Lele B. S., Lele B. S., Li K., Magnusson J. P., Mantovani G., Mathew W. Jones, McFarland J. M., Ouchi M., Patai S., Patai S., Pauly H. Z., Rafii F., Roberts M. J., Romanini D. W., Ryan S. M., Sams C. F., Sayers C. T., Sayers C. T., Schalk I., Schlick T. L., Sinead M. Ryan, Southam R. M., Szurdoki F., Tao L., Tilley S. D., Tracey B. M., Vaughan K., Veronese F. M., Vilaro M., Wang J.-S., White E. H., Wong S. S., Xuexuan Wang, Yasayan G., Zloh M.   +64 more
core   +1 more source

Metal-Binding Ability of Leu-Enkephalin, Related Glycoconjugates and Peptidomimetics

Croatica Chemica Acta, 2015
Both the chemistry and consequences of the nonenzymatic reaction between reducing sugars and reactive amino groups of amino acids, peptides and proteins (known as the Maillard reaction), have received considerable attention in food and health science ...
Zsuzsa Majer, Elemér Vass, Maja Roščić, Miklós Hollósi, Štefica Horvat, Andreja Jakas   +5 more
doaj   +1 more source

An Immunocytochemical Study of Endocrine Cells in the Gut of a Stomachless Teleost Fish, Grass Carp, Cyprinidae

Cell Transplantation, 1993
Nineteen different antisera raised against mammalian hormones were used to identify the occurrence and distribution of endocrine cells in the gut of grass carp (Ctenopharyngodon idellus).
Qian-Sheng Pan, Zhi-Ping Fang
doaj   +1 more source

Kinetics of chymotrypsin- and papain-catalysed synthesis of [leucine]enkephalin and [methionine]enkephalin [PDF]

Biochemical Journal, 1984
The proteinase-catalysed synthesis of [Leu]enkephalin and [Met]enkephalin was studied kinetically. N alpha-t-Butoxycarbonyl-amino acids and peptides or their ethyl esters served as acyl donors, and amino acid phenylhydrazides were used as acyl acceptors.
openaire   +3 more sources

Embracing Complexity: Peptides as Tunable Scaffolds in the Construction of Discrete Supramolecular Systems

Angewandte Chemie, Volume 137, Issue 34, August 18, 2025.
The inherent chirality, tunability, biocompatibility, and robustness of peptides provide an exciting opportunity for supramolecular chemistry. In this mini‐review, we explore uses of peptides in discrete supramolecular systems, how chemists can draw inspiration from larger biological assemblies, and discuss how embracing the complexity of peptide ...
Ben E. Barber, Ellen M. G. Jamieson, Leah E. M. White, Charlie T. McTernan   +3 more
wiley   +2 more sources