Results 41 to 50 of about 15,501 (138)

Characterization and Identification of Potential Antioxidant, Antidiabetic, and Antihypertensive Peptides From Hydrolysates of Tenebrio molitor Flour and Its Protein Concentrate

Journal of Food Science, Volume 90, Issue 10, October 2025.
ABSTRACT Insects are recognized as a potential alternative source of proteins and have been studied in recent years as a substrate for enzymatic hydrolysis to obtain bioactive peptides. This study aimed to evaluate the production of hydrolysates with antioxidant, antidiabetic, and antihypertensive properties from mealworm (Tenebrio molitor) flour and ...
Francielle Miranda de Matos, Ruann Janser Soares de Castro   +1 more
wiley   +1 more source

Identification of MscS as a Key L‐Glutamate Exporter in Bacillus methanolicus

Microbial Biotechnology, Volume 18, Issue 10, October 2025.
l‐Glutamate export in the methylotrophic bacterium Bacillus methanolicus, driven by an MscS‐like mechanosensitive channel. Figure created with BioRender (https://BioRender.com/t99s28). ABSTRACT Small‐conductance mechanosensitive channels (MscS) are established l‐glutamate exporters in industrially relevant bacteria, yet their role in the methylotrophic
Luciana Fernandes Brito, Davide Luciano, Marta Irla, David Virant, Gaston Courtade, Trygve Brautaset   +5 more
wiley   +1 more source

Photodissociation of protonated Leucine-Enkephalin peptide in the VUV range

Journal of Physics: Conference Series, 2015
We present results of VUV action spectroscopy of gas-phase protonated Leucin-Enkephalin peptide. The experiment has been performed by coupling a linear quadrupole ion trap with a synchrotron radiation VUV beamline.
Ranković, Milos Lj., Cerovski, Victor Z., Canon, Francis, Nahon, Laurent, Giuliani, Alexandre, Milosavljević, Aleksandar R.   +5 more
openaire   +4 more sources

Exosome‐Based Therapeutics: A Natural Solution to Overcoming the Blood–Brain Barrier in Neurodegenerative Diseases

MedComm, Volume 6, Issue 9, September 2025.
Therapies for neurodegenerative diseases (NDs) are constrained by the blood–brain barrier (BBB), which limits drug delivery. Exosomes, with their ability to cross BBB and deliver drugs efficiently, emerge as a promising platform for central nervous system‐targeted therapies. ABSTRACT Neurodegenerative diseases present significant therapeutic challenges,
Min Sun, Feng Qin, Qian Bu, Yue Zhao, Xiaofeng Yang, Dingwen Zhang, Xiaobo Cen   +6 more
wiley   +1 more source

Lentil Flours as Sustainable Source of Proteins for the Food Industry

Sustainable Food Proteins, Volume 3, Issue 3, September 2025.
Lentils, due to their accessibility, sustainability, and high nutritional value, emerge as a promising option as protein flour for food development. This study evaluated different functional and nutritional properties of lentil flours. ABSTRACT The growing transition toward a plant‐based diet, coupled with the need for sustainable dietary protein ...
S. M. Pontoni, A.G. Garzón, G. D. Heinen, S.R. Drago   +3 more
wiley   +1 more source

Research of the analgesic effects and central nervous system impact of electroacupuncture therapy in rats with knee osteoarthritis

Heliyon
It aimed to observe the effects of TongDu TiaoShen (TDTS) electroacupuncture (EA) on the analgesia and central system of knee osteoarthritis (KOA) rats and explore its mechanism. SD rats were rolled into the blank group, model group (KOA), control group (
Xiahai Zheng, Jing Lin, Zhenzhen Wang, Zhenming Zeng, Haoxiong Chen   +4 more
doaj   +1 more source

LC‐MS Analysis and Antimicrobial Activity of Different Extracts of Spondias purpurea L

ChemistrySelect, Volume 10, Issue 34, September 8, 2025.
The present research showed that the extracts tested alone do not present significant antibacterial or antifungal activities at low concentrations against the tested strains. However, they demonstrated potentiating effect of already standardized drugs. Abstract Spondias purpurea L.
Maria Elenilda Paulino da Silva, Joara Nályda Pereira Carneiro, Carlos Vinicius Barros Oliveira, Antonia Thassya Lucas dos Santos, Rafael Pereira da Cruz, Débora Lima Sales, José Weverton Almeida‐Bezerra, Viviane Bezerra da Silva, Adrielle Rodrigues Costa, Jacqueline Cosmo Andrade‐Pinheiro, Gyllyandeson de Araújo Delmondes, Paulo Riceli Vasconcelos Ribeiro, Edy Sousa de Brito, Catarina Martins Tahim, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais‐Braga   +15 more
wiley   +1 more source

Untargeted metabolomics reveals key metabolites and genes underlying salinity tolerance mechanisms in maize

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Understanding the physiological, metabolic, and genetic mechanisms underlying salt tolerance is essential for improving crop resilience and productivity, yet their complex interactions remain poorly defined. We compared physiological and metabolic responses to salinity between two contrasting maize (Zea mays L.) inbred lines: the salt ...
Manwinder S. Brar, Amancio De Souza, Avineet Ghai, Jorge F. S. Ferreira, Devinder Sandhu, Rajandeep S. Sekhon   +5 more
wiley   +1 more source

Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia

Journal of Neurochemistry, Volume 169, Issue 9, September 2025.
Microglia, the brain's immune cells, change their metabolism depending on whether they are fighting infection or promoting healing. This study shows that during inflammation, microglia increase a molecule called itaconate, which helps reduce harmful stress in the brain while still allowing an immune response.
Pinelopi Engskog‐Vlachos, Mikael K. R. Engskog, Martin Skandik, Kathleen Grabert, Noah Moruzzi, Marie‐Kim St‐Pierre, Ahmed M. Osman, Theodora Sylaidi, Klas Blomgren, Per‐Olof Berggren, Bertrand Joseph   +10 more
wiley   +1 more source

Electroacupuncture attenuates retinal ischemia/reperfusion injury by protecting the outer blood-retina barrier via enkephalins activate delta opioid receptor

World Journal of Acupuncture - Moxibustion
Objectives: Retinal ischemia-reperfusion (RIR) injury results in irreversible visual impairments. The disruption of the outer blood-retinal barrier (OBRB) is a major ocular pathogenic process that RIR injury affects.
Ping CHEN, Xian-dan ZHU, Run-jie GUO, Yong XIA, Jing-ling JIN, Nan-ge JIN, Ying-min GU, Xue-song TIAN   +7 more
doaj   +1 more source