Results 31 to 40 of about 9,174 (179)
How Far Does a Receptor Influence Vibrational Properties of an Odorant? [PDF]
, 2016 The biophysical mechanism of the sense of smell, or olfaction, is still highly debated. The mainstream explanation argues for a shape-based recognition of odorant molecules by olfactory receptors, while recent investigations suggest the primary olfactory
Kongsted, Jacob +3 more
core +10 more sources
Backbone Protecting Groups for Enhanced Peptide and Protein Synthesis
Angewandte Chemie, Volume 137, Issue 33, August 11, 2025.This review provides a comprehensive account of the use of backbone N‐protecting groups in peptide synthesis. It includes detailed synthetic methods relating to their introduction and removal and their application to “difficult” peptides and proteins of biological significance in both academic and industry contexts.
Samuel J. Paravizzini +3 more
wiley +2 more sources
Biomimetic Chemistry on Tandem Protein/Lipid Damages under Reductive Radical Stress
CHIMIA, 2008 The study of radical stress in the biological environment needs a comprehensive vision of all possible reactive species and their mechanisms. Among them, reductive stress is evaluated for its selective target of sulfur-containing compounds.
Sílvia Atrian +8 more
doaj +1 more source
Met-enkephalin-induced mobilization of intracellular Ca2+ in rat intracardiac ganglion neurones [PDF]
, 1999 The effects of Met-enkephalin on Ca2+-dependent K+ channel activity were investigated using the cell-attached patch recording technique on isolated parasympathetic neurones of rat intracardiac ganglia. Large-conductance, Ca2+-dependent K+ channels (BKCa)
Adams +18 more
core +1 more source
High resolution NMR study of T1 magnetic relaxation dispersion. IV. Proton relaxation in amino acids and Met-enkephalin pentapeptide [PDF]
, 2014 Nuclear Magnetic Relaxation Dispersion (NMRD) of protons was studied in the pentapeptide Met-enkephalin and the amino acids, which constitute it. Experiments were run by using high-resolution Nuclear Magnetic Resonance (NMR) in combination with fast ...
Ivanov, Konstantin L. +3 more
core +1 more source
Dynamic Metabolic Footprinting Reveals the Key Components of Metabolic Network in Yeast Saccharomyces cerevisiae [PDF]
, 2014 Metabolic footprinting offers a relatively easy approach to exploit the potentials of metabolomics for phenotypic characterization of microbial cells.
Chumnanpuen, Pramote +3 more
core +3 more sources
Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]
, 1995 Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core +1 more source
Multi-physics Extension of OpenFMO Framework
, 2007 OpenFMO framework, an open-source software (OSS) platform for Fragment Molecular Orbital (FMO) method, is extended to multi-physics simulations (MPS). After reviewing the several FMO implementations on distributed computer environments, the subsequent ...
George Maroulis +11 more
core +1 more source
Complex Regional Pain Syndrome and Methionine-Enkephalin [PDF]
Clinical Chemistry, 2006 Complex regional pain syndrome (CRPS), or reflex sympathetic dystrophy, develops after trauma or surgery and is characterized by pain that is disproportionate to the initial injury and is not confined to the nerve or nerve root distribution (1)(2)(3)(4)(5). Symptoms involve the autonomic, somatosensory, and sympathetic nervous systems.
Olivier W V, van den Brink +5 more
openaire +2 more sources
Movement Disorders, EarlyView.Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag +14 more
wiley +1 more source