Responses of substantia gelatinosa neurons to putative neurotransmitters in an in vitro preparation of the adult rat spinal cord [PDF]
, 1983 Extracellular recordings were performed from neurons of the substantia gelatinosa (SG) in an in vitro preparation obtained from the spinal cord of adult rats. About 40% of neurons were spontaneously active.
B. Sutor +29 more
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Acetaldehyde‐enkephalins: pronounced changes in the opiate activity of methionine‐enkephalin and leucine‐enkephalin on reaction with acetaldehyde [PDF]
FEBS Letters, 1980 We have shown that the two major endogenous opioid peptides, methionine-enkephalin and leucineenkephalin [ 1,2] (enkephalin [Met’] and enkephalin[Leu’]) rapidly react with acetaldehyde in aqueous buffers to give a stable ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin[Met’]’ and ‘acetaldehyde-enkephalin [Leu’]‘, respectively ...
Roger J. Hayes, Michael C. Summers
openaire +3 more sources
Annals of Hepatology, 2008 Endogenous opioids participate in growth regulation. Liver regeneration relates to growth. Thus, we explored the expression of methionine enkephalin and of the delta opioid receptor 1 immunoreactivities with a polyclonal rabbit antibody in deparaffinized
Vijaya D. Boyella +2 more
doaj +1 more source
Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]
, 2013 The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
Bongiorno, David +7 more
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Great Increase in Antinociceptive Potency of [Leu5]Enkephalin After Peptidase Inhibition
Journal of Pharmacological Sciences, 2008 Previous in vitro studies have shown that the degradation of [Leu5]enkephalin during incubation with cerebral membrane preparations is almost completely prevented by a mixture of three peptidase inhibitors: amastatin, captopril, and phosphoramidon.
Kazuhito Akahori +6 more
doaj +1 more source
Biomolecules & Biomedicine, 2014 Endogenious opiod met-enkephalin throughout previous research manifested cytoprotective and anti-inflammatory effects. Previous research suggests that met-enkephalin has cytogenetic effects.
Maida Rakanović-Todić +3 more
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Characteristic Temperatures of Folding of a Small Peptide [PDF]
, 1997 We perform a generalized-ensemble simulation of a small peptide taking the interactions among all atoms into account. From this simulation we obtain thermodynamic quantities over a wide range of temperatures.
Anfinsen +25 more
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Enkephalin as a Pivotal Player in Neuroadaptations Related to Psychostimulant Addiction
Frontiers in Psychiatry, 2018 Enkephalin expression is high in mesocorticolimbic areas associated with psychostimulant-induced behavioral and neurobiological effects, and may also modulate local neurotransmission in this circuit network.
Bethania Mongi-Bragato +4 more
doaj +1 more source
Involvement of the Opioid Peptide Family in Cancer Progression
Biomedicines, 2023 Peptides mediate cancer progression favoring the mitogenesis, migration, and invasion of tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating angiogenesis/lymphangiogenesis.
Manuel Lisardo Sánchez +2 more
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Effects of Long-term antipsychotic treatment on enkephalin-immunoreactive neurons in rats perinatally treated with phencyclidine [PDF]
Medicinski Podmladak, 2023 Introduction: Schizophrenia is a chronic mental illness that affects 1% of the world's population. The phencyclidine animal model of schizophrenia is based on the glutamate theory of the development of schizophrenia.
Kompanijec Anja +2 more
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